ORBIMED ADVISORS LLC Holdings

ORBIMED ADVISORS LLC is an investment fund managing more than 5.39B US dollars. The largest holdings include Sinovac Biotech Ltd., Bristol-Myers Squibb Company and Humana. In Q3 2022 the fund bought assets of total value of 723.87M US dollars and sold assets of total value of 637.1M US dollars.

$5.38B

portfolio value

+4.14%

quarter

-33.80%

1 year

-44.97%

3 years

+1.41%

5 years

ORBIMED ADVISORS LLC portfolio changes

Portfolio changes (number of shares)
Period	Buy	Sel
Q1 2016	98945000	1120152000
Q2 2016	1199078000	1138262000
Q3 2016	1077175000	1628799000
Q4 2016	1002597000	1476018000
Q1 2017	1138401000	387709000
Q2 2017	1592191000	942009000
Q3 2017	1261877000	543855000
Q4 2017	343232000	2621112000
Q1 2018	1473685000	1387512000
Q2 2018	1302378000	938017000
Q3 2018	1086874000	1122931000
Q4 2018	419024000	2699633000
Q1 2019	1201595000	583250000
Q2 2019	960212000	702739000
Q3 2019	365962000	1266077000
Q4 2019	1292671000	55347000
Q1 2020	1167544000	1207572000
Q2 2020	1313227000	662223000
Q3 2020	1653956000	510015000
Q4 2020	2182579000	586028000
Q1 2021	2434747000	2311709000
Q2 2021	898554000	601489000
Q3 2021	851315000	893439000
Q4 2021	907139000	1336801000
Q1 2022	260607000	1247023000
Q2 2022	538473000	753937000
Q3 2022	723869000	637103000

ORBIMED ADVISORS LLC 13F holdings

Stock	Position type	Portfolio share	Portfolio value	Avg. open price	Current price	P/L	Last change
Biotechnology Sinovac Biotech Ltd. Portfolio share: 6.32% Portfolio value: 340.5M Avg. open price: $7.05 Current price: $6.47 P/L: -8.23% N/A Q2 2022	share	6.32%	340.5M	$7.05	$6.47	-8.23%	N/A Q2 2022
Drug Manufacturers—General Bristol-Myers Squibb Company Portfolio share: 3.41% Portfolio value: 183.76M Avg. open price: $54.93 Current price: $80.7 P/L: +46.91% Bought +2.63% shares Q3 2022	share	3.41%	183.76M	$54.93	$80.7	+46.91%	Bought +2.63% shares Q3 2022
Healthcare Plans Humana Inc. Portfolio share: 3.14% Portfolio value: 169.18M Avg. open price: $246.32 Current price: $547.42 P/L: +122.24% Sold -4.65% shares Q3 2022	share	3.14%	169.18M	$246.32	$547.42	+122.24%	Sold -4.65% shares Q3 2022
Biotechnology SpringWorks Therapeutics, Inc. Portfolio share: 2.93% Portfolio value: 157.65M Avg. open price: N/A Current price: $24.25 P/L: N/A Sold -8.33% shares Q3 2022	share	2.93%	157.65M	N/A	$24.25	N/A	Sold -8.33% shares Q3 2022
Medical Devices Boston Scientific Corporation Portfolio share: 2.80% Portfolio value: 150.97M Avg. open price: $35.07 Current price: $45.42 P/L: +29.53% Sold -10.79% shares Q3 2022	share	2.80%	150.97M	$35.07	$45.42	+29.53%	Sold -10.79% shares Q3 2022
Biotechnology BioMarin Pharmaceutical Inc. Portfolio share: 2.70% Portfolio value: 145.57M Avg. open price: $88.8 Current price: $103.53 P/L: +16.58% Bought +1.04% shares Q3 2022	share	2.70%	145.57M	$88.8	$103.53	+16.58%	Bought +1.04% shares Q3 2022
Biotechnology Edgewise Therapeutics, Inc. Portfolio share: 2.66% Portfolio value: 143.34M Avg. open price: $8.35 Current price: $8.83 P/L: +5.80% Bought +3.44% shares Q3 2022	share	2.66%	143.34M	$8.35	$8.83	+5.80%	Bought +3.44% shares Q3 2022
Healthcare Plans UnitedHealth Group Incorporated Portfolio share: 2.50% Portfolio value: 134.94M Avg. open price: $132.62 Current price: $535.04 P/L: +303.45% Sold -4.98% shares Q3 2022	share	2.50%	134.94M	$132.62	$535.04	+303.45%	Sold -4.98% shares Q3 2022
Drug Manufacturers—General Pfizer Inc. Portfolio share: 2.11% Portfolio value: 113.73M Avg. open price: $38.32 Current price: $50.73 P/L: +32.37% Sold -5.28% shares Q3 2022	share	2.11%	113.73M	$38.32	$50.73	+32.37%	Sold -5.28% shares Q3 2022
Biotechnology Third Harmonic Bio, Inc. Portfolio share: 2.04% Portfolio value: 109.62M Avg. open price: N/A Current price: $22 P/L: N/A N/A Q3 2022	share	2.04%	109.62M	N/A	$22	N/A	N/A Q3 2022
Biotechnology Vertex Pharmaceuticals Incorporated Portfolio share: 2.01% Portfolio value: 108.05M Avg. open price: $135.15 Current price: $317.6 P/L: +135.00% Sold -3.62% shares Q3 2022	share	2.01%	108.05M	$135.15	$317.6	+135.00%	Sold -3.62% shares Q3 2022
Biotechnology Tricida, Inc. Portfolio share: 2.00% Portfolio value: 107.74M Avg. open price: $13.21 Current price: $0.23 P/L: -98.28% Bought +6.93% shares Q4 2021	share	2.00%	107.74M	$13.21	$0.23	-98.28%	Bought +6.93% shares Q4 2021
Medical Instruments & Supplies Intuitive Surgical, Inc. Portfolio share: 1.99% Portfolio value: 107.34M Avg. open price: $156.32 Current price: $269.72 P/L: +72.54% Bought +10.73% shares Q3 2022	share	1.99%	107.34M	$156.32	$269.72	+72.54%	Bought +10.73% shares Q3 2022
Biotechnology Adicet Bio, Inc. Portfolio share: 1.97% Portfolio value: 105.89M Avg. open price: $12.25 Current price: $20.2 P/L: +64.92% Sold -0.00% shares Q3 2022	share	1.97%	105.89M	$12.25	$20.2	+64.92%	Sold -0.00% shares Q3 2022
Biotechnology Seagen Inc. Portfolio share: 1.94% Portfolio value: 104.34M Avg. open price: $169.54 Current price: $121.22 P/L: -28.50% Bought +10.92% shares Q3 2022	share	1.94%	104.34M	$169.54	$121.22	-28.50%	Bought +10.92% shares Q3 2022
Diagnostics & Research Thermo Fisher Scientific Inc. Portfolio share: 1.90% Portfolio value: 102.55M Avg. open price: $288.5 Current price: $557.21 P/L: +93.14% Bought +78.31% shares Q3 2022	share	1.90%	102.55M	$288.5	$557.21	+93.14%	Bought +78.31% shares Q3 2022
Biotechnology Sarepta Therapeutics, Inc. Portfolio share: 1.88% Portfolio value: 101.53M Avg. open price: $90.27 Current price: $122.96 P/L: +36.21% Bought +4492.50% shares Q3 2022	share	1.88%	101.53M	$90.27	$122.96	+36.21%	Bought +4492.50% shares Q3 2022
Biotechnology Mirati Therapeutics, Inc. Portfolio share: 1.84% Portfolio value: 99.09M Avg. open price: $97.46 Current price: $92.75 P/L: -4.83% Bought +30.13% shares Q3 2022	share	1.84%	99.09M	$97.46	$92.75	-4.83%	Bought +30.13% shares Q3 2022
Biotechnology Theseus Pharmaceuticals, Inc. Portfolio share: 1.83% Portfolio value: 98.84M Avg. open price: $12.28 Current price: $6.03 P/L: -50.90% Bought +1.21% shares Q1 2022	share	1.83%	98.84M	$12.28	$6.03	-50.90%	Bought +1.21% shares Q1 2022
Drug Manufacturers—Specialty & Generic Neurocrine Biosciences, Inc. Portfolio share: 1.77% Portfolio value: 95.22M Avg. open price: $81.31 Current price: $124 P/L: +52.50% Bought +5.53% shares Q3 2022	share	1.77%	95.22M	$81.31	$124	+52.50%	Bought +5.53% shares Q3 2022
Biotechnology argenx SE Portfolio share: 1.77% Portfolio value: 95.21M Avg. open price: $170.07 Current price: $393.21 P/L: +131.20% Bought +39.02% shares Q3 2022	share	1.77%	95.21M	$170.07	$393.21	+131.20%	Bought +39.02% shares Q3 2022
Medical Devices Stryker Corporation Portfolio share: 1.59% Portfolio value: 85.69M Avg. open price: $185.28 Current price: $237.9 P/L: +28.40% Sold -4.08% shares Q3 2022	share	1.59%	85.69M	$185.28	$237.9	+28.40%	Sold -4.08% shares Q3 2022
Drug Manufacturers—General AbbVie Inc. Portfolio share: 1.49% Portfolio value: 80.52M Avg. open price: $85.82 Current price: $163.96 P/L: +91.05% Sold -24.98% shares Q3 2022	share	1.49%	80.52M	$85.82	$163.96	+91.05%	Sold -24.98% shares Q3 2022
Medical Devices Edwards Lifesciences Corporation Portfolio share: 1.48% Portfolio value: 79.84M Avg. open price: $38.76 Current price: $73.85 P/L: +90.51% Sold -4.45% shares Q3 2022	share	1.48%	79.84M	$38.76	$73.85	+90.51%	Sold -4.45% shares Q3 2022
Biotechnology PMV Pharmaceuticals, Inc. Portfolio share: 1.45% Portfolio value: 78.10M Avg. open price: N/A Current price: $9.89 P/L: N/A Sold -4.26% shares Q2 2022	share	1.45%	78.10M	N/A	$9.89	N/A	Sold -4.26% shares Q2 2022
Health Information Services Evolent Health, Inc. Portfolio share: 1.33% Portfolio value: 71.67M Avg. open price: $30.33 Current price: $28.66 P/L: -5.50% Bought +12.19% shares Q3 2022	share	1.33%	71.67M	$30.33	$28.66	-5.50%	Bought +12.19% shares Q3 2022
Biotechnology Prelude Therapeutics Incorporated Portfolio share: 1.23% Portfolio value: 66.36M Avg. open price: N/A Current price: $6.2 P/L: N/A Sold -35.62% shares Q1 2021	share	1.23%	66.36M	N/A	$6.2	N/A	Sold -35.62% shares Q1 2021
Diagnostics & Research Natera, Inc. Portfolio share: 1.22% Portfolio value: 65.95M Avg. open price: $27.36 Current price: $40.39 P/L: +47.62% Sold -9.40% shares Q3 2022	share	1.22%	65.95M	$27.36	$40.39	+47.62%	Sold -9.40% shares Q3 2022
Biotechnology Keros Therapeutics, Inc. Portfolio share: 1.17% Portfolio value: 63.18M Avg. open price: N/A Current price: $50 P/L: N/A N/A Q2 2020	share	1.17%	63.18M	N/A	$50	N/A	N/A Q2 2020
Biotechnology Crinetics Pharmaceuticals, Inc. Portfolio share: 1.17% Portfolio value: 62.78M Avg. open price: $16.59 Current price: $18.32 P/L: +10.46% Bought +6.67% shares Q4 2021	share	1.17%	62.78M	$16.59	$18.32	+10.46%	Bought +6.67% shares Q4 2021
Biotechnology Mersana Therapeutics, Inc. Portfolio share: 1.13% Portfolio value: 60.91M Avg. open price: $8.71 Current price: $7.05 P/L: -19.06% Bought +88.17% shares Q2 2022	share	1.13%	60.91M	$8.71	$7.05	-19.06%	Bought +88.17% shares Q2 2022
IKENA ONCOLOGY INC Portfolio share: 1.12% Portfolio value: 60.50M Avg. open price: N/A Current price: N/A P/L: N/A Bought +2.12% shares Q2 2022	share	1.12%	60.50M	N/A	N/A	N/A	Bought +2.12% shares Q2 2022
Drug Manufacturers—General Biogen Inc. Portfolio share: 1.11% Portfolio value: 59.96M Avg. open price: $291.42 Current price: $292.75 P/L: +0.46% Bought +101.25% shares Q3 2022	share	1.11%	59.96M	$291.42	$292.75	+0.46%	Bought +101.25% shares Q3 2022
Medical Devices SI-BONE, Inc. Portfolio share: 1.09% Portfolio value: 58.80M Avg. open price: $26.3 Current price: $12.08 P/L: -54.07% Bought +7.29% shares Q2 2022	share	1.09%	58.80M	$26.3	$12.08	-54.07%	Bought +7.29% shares Q2 2022
Biotechnology Verona Pharma plc Portfolio share: 1.08% Portfolio value: 58.20M Avg. open price: $5.92 Current price: $13.57 P/L: +129.27% Bought +355.44% shares Q3 2020	share	1.08%	58.20M	$5.92	$13.57	+129.27%	Bought +355.44% shares Q3 2020
Biotechnology Arcutis Biotherapeutics, Inc. Portfolio share: 0.99% Portfolio value: 53.50M Avg. open price: $29.3 Current price: $17.35 P/L: -40.78% Sold -41.44% shares Q3 2022	share	0.99%	53.50M	$29.3	$17.35	-40.78%	Sold -41.44% shares Q3 2022
Diagnostics & Research Guardant Health, Inc. Portfolio share: 0.99% Portfolio value: 53.42M Avg. open price: $125.95 Current price: $51.95 P/L: -58.75% Sold -3.97% shares Q3 2022	share	0.99%	53.42M	$125.95	$51.95	-58.75%	Sold -3.97% shares Q3 2022
Medical Devices Xtant Medical Holdings, Inc. Portfolio share: 0.98% Portfolio value: 52.62M Avg. open price: $0.87 Current price: $0.58 P/L: -33.62% Bought +0.23% shares Q3 2022	share	0.98%	52.62M	$0.87	$0.58	-33.62%	Bought +0.23% shares Q3 2022
Biotechnology Alnylam Pharmaceuticals, Inc. Portfolio share: 0.93% Portfolio value: 50.14M Avg. open price: $79.35 Current price: $226.4 P/L: +185.31% N/A Q3 2022	share	0.93%	50.14M	$79.35	$226.4	+185.31%	N/A Q3 2022
Biotechnology Compass Therapeutics, Inc. Portfolio share: 0.93% Portfolio value: 50.07M Avg. open price: $1.37 Current price: $4.53 P/L: +230.66% Bought +1.47% shares Q2 2022	share	0.93%	50.07M	$1.37	$4.53	+230.66%	Bought +1.47% shares Q2 2022
Biotechnology BELLUS Health Inc. Portfolio share: 0.91% Portfolio value: 48.97M Avg. open price: $9.24 Current price: $10.02 P/L: +8.44% Bought +218.59% shares Q3 2022	share	0.91%	48.97M	$9.24	$10.02	+8.44%	Bought +218.59% shares Q3 2022
Biotechnology Kinnate Biopharma Inc. Portfolio share: 0.90% Portfolio value: 48.32M Avg. open price: $18.16 Current price: $7.05 P/L: -61.18% Bought +5.09% shares Q1 2022	share	0.90%	48.32M	$18.16	$7.05	-61.18%	Bought +5.09% shares Q1 2022
Biotechnology Syndax Pharmaceuticals, Inc. Portfolio share: 0.90% Portfolio value: 48.21M Avg. open price: $16.68 Current price: $25.44 P/L: +52.48% Sold -13.64% shares Q3 2022	share	0.90%	48.21M	$16.68	$25.44	+52.48%	Sold -13.64% shares Q3 2022
Biotechnology Silverback Therapeutics, Inc. Portfolio share: 0.86% Portfolio value: 46.15M Avg. open price: N/A Current price: $5.87 P/L: N/A N/A Q4 2020	share	0.86%	46.15M	N/A	$5.87	N/A	N/A Q4 2020
Biotechnology Terns Pharmaceuticals, Inc. Portfolio share: 0.82% Portfolio value: 44.06M Avg. open price: $2.48 Current price: $6.09 P/L: +145.56% Bought +97.33% shares Q3 2022	share	0.82%	44.06M	$2.48	$6.09	+145.56%	Bought +97.33% shares Q3 2022
Diagnostics & Research Aclaris Therapeutics, Inc. Portfolio share: 0.81% Portfolio value: 43.41M Avg. open price: $16.07 Current price: $15.66 P/L: -2.56% Bought +18.62% shares Q3 2022	share	0.81%	43.41M	$16.07	$15.66	-2.56%	Bought +18.62% shares Q3 2022
Health Information Services Progyny, Inc. Portfolio share: 0.78% Portfolio value: 42.02M Avg. open price: $28.58 Current price: $34.07 P/L: +19.23% Bought +81.45% shares Q3 2022	share	0.78%	42.02M	$28.58	$34.07	+19.23%	Bought +81.45% shares Q3 2022
Biotechnology AbCellera Biologics Inc. Portfolio share: 0.77% Portfolio value: 41.34M Avg. open price: N/A Current price: $11.91 P/L: N/A Sold -32.82% shares Q3 2021	share	0.77%	41.34M	N/A	$11.91	N/A	Sold -32.82% shares Q3 2021
Biotechnology Xenon Pharmaceuticals Inc. Portfolio share: 0.76% Portfolio value: 41.05M Avg. open price: $17.21 Current price: $38.83 P/L: +125.66% Sold -14.44% shares Q3 2022	share	0.76%	41.05M	$17.21	$38.83	+125.66%	Sold -14.44% shares Q3 2022
Biotechnology Repare Therapeutics Inc. Portfolio share: 0.75% Portfolio value: 40.30M Avg. open price: N/A Current price: $16.49 P/L: N/A Sold -3.03% shares Q3 2021	share	0.75%	40.30M	N/A	$16.49	N/A	Sold -3.03% shares Q3 2021
Biotechnology Chinook Therapeutics, Inc. Portfolio share: 0.74% Portfolio value: 39.89M Avg. open price: $16.22 Current price: $22.77 P/L: +40.42% Bought +7.01% shares Q3 2022	share	0.74%	39.89M	$16.22	$22.77	+40.42%	Bought +7.01% shares Q3 2022
VECTIVBIO HLDG AG Portfolio share: 0.72% Portfolio value: 38.84M Avg. open price: N/A Current price: N/A P/L: N/A Bought +21.44% shares Q2 2022	share	0.72%	38.84M	N/A	N/A	N/A	Bought +21.44% shares Q2 2022
Biotechnology Janux Therapeutics, Inc. Portfolio share: 0.71% Portfolio value: 38.40M Avg. open price: N/A Current price: $13.5 P/L: N/A Sold -18.17% shares Q4 2021	share	0.71%	38.40M	N/A	$13.5	N/A	Sold -18.17% shares Q4 2021
Biotechnology Ionis Pharmaceuticals, Inc. Portfolio share: 0.63% Portfolio value: 34.00M Avg. open price: $37.02 Current price: $38.98 P/L: +5.29% Bought +69.59% shares Q3 2022	share	0.63%	34.00M	$37.02	$38.98	+5.29%	Bought +69.59% shares Q3 2022
Medical Care Facilities Tenet Healthcare Corporation Portfolio share: 0.62% Portfolio value: 33.18M Avg. open price: $25.55 Current price: $44.6 P/L: +74.55% Sold -1.98% shares Q3 2022	share	0.62%	33.18M	$25.55	$44.6	+74.55%	Sold -1.98% shares Q3 2022
Biotechnology scPharmaceuticals Inc. Portfolio share: 0.58% Portfolio value: 31.27M Avg. open price: $7.4 Current price: $6.9 P/L: -6.76% Bought +40.68% shares Q2 2020	share	0.58%	31.27M	$7.4	$6.9	-6.76%	Bought +40.68% shares Q2 2020
Biotechnology Travere Therapeutics, Inc. Portfolio share: 0.57% Portfolio value: 30.87M Avg. open price: $24.23 Current price: $20.01 P/L: -17.42% Bought +62.28% shares Q3 2022	share	0.57%	30.87M	$24.23	$20.01	-17.42%	Bought +62.28% shares Q3 2022
Biotechnology RAPT Therapeutics, Inc. Portfolio share: 0.56% Portfolio value: 30.10M Avg. open price: $22.59 Current price: $16.53 P/L: -26.84% Bought +44.40% shares Q3 2022	share	0.56%	30.10M	$22.59	$16.53	-26.84%	Bought +44.40% shares Q3 2022
Biotechnology uniQure N.V. Portfolio share: 0.56% Portfolio value: 29.96M Avg. open price: $20.84 Current price: $25.65 P/L: +23.09% Bought +82.55% shares Q3 2022	share	0.56%	29.96M	$20.84	$25.65	+23.09%	Bought +82.55% shares Q3 2022
Biotechnology Alpine Immune Sciences, Inc. Portfolio share: 0.55% Portfolio value: 29.38M Avg. open price: $7.57 Current price: $6.78 P/L: -10.47% Bought +32.91% shares Q3 2021	share	0.55%	29.38M	$7.57	$6.78	-10.47%	Bought +32.91% shares Q3 2021
Biotechnology ALX Oncology Holdings Inc. Portfolio share: 0.51% Portfolio value: 27.47M Avg. open price: $16.65 Current price: $11.92 P/L: -28.43% Bought +31.32% shares Q3 2022	share	0.51%	27.47M	$16.65	$11.92	-28.43%	Bought +31.32% shares Q3 2022
Biotechnology Biohaven Ltd. Portfolio share: 0.48% Portfolio value: 25.81M Avg. open price: N/A Current price: $16.32 P/L: N/A Sold -76.25% shares Q3 2022	share	0.48%	25.81M	N/A	$16.32	N/A	Sold -76.25% shares Q3 2022
Medical Devices TELA Bio, Inc. Portfolio share: 0.48% Portfolio value: 25.79M Avg. open price: N/A Current price: $8.6 P/L: N/A N/A Q4 2019	share	0.48%	25.79M	N/A	$8.6	N/A	N/A Q4 2019
Biotechnology Gracell Biotechnologies Inc. Portfolio share: 0.47% Portfolio value: 25.38M Avg. open price: N/A Current price: $2.87 P/L: N/A N/A Q1 2021	share	0.47%	25.38M	N/A	$2.87	N/A	N/A Q1 2021
Biotechnology 89bio, Inc. Portfolio share: 0.39% Portfolio value: 21.18M Avg. open price: N/A Current price: $8.34 P/L: N/A Sold -1.89% shares Q1 2022	share	0.39%	21.18M	N/A	$8.34	N/A	Sold -1.89% shares Q1 2022
Biotechnology Iovance Biotherapeutics, Inc. Portfolio share: 0.36% Portfolio value: 19.23M Avg. open price: $13.74 Current price: $8.03 P/L: -41.55% Sold -28.27% shares Q3 2022	share	0.36%	19.23M	$13.74	$8.03	-41.55%	Sold -28.27% shares Q3 2022
Biotechnology GH Research PLC Portfolio share: 0.35% Portfolio value: 18.84M Avg. open price: $18.29 Current price: $11.4 P/L: -37.68% Bought +13.53% shares Q2 2022	share	0.35%	18.84M	$18.29	$11.4	-37.68%	Bought +13.53% shares Q2 2022
Biotechnology MeiraGTx Holdings plc Portfolio share: 0.33% Portfolio value: 17.72M Avg. open price: $14.54 Current price: $6.49 P/L: -55.39% Sold -15.73% shares Q3 2022	share	0.33%	17.72M	$14.54	$6.49	-55.39%	Sold -15.73% shares Q3 2022
Biotechnology Vaxcyte, Inc. Portfolio share: 0.32% Portfolio value: 17.23M Avg. open price: $23.26 Current price: $44.33 P/L: +90.61% Sold -52.57% shares Q3 2022	share	0.32%	17.23M	$23.26	$44.33	+90.61%	Sold -52.57% shares Q3 2022
Biotechnology Decibel Therapeutics, Inc. Portfolio share: 0.32% Portfolio value: 17.11M Avg. open price: N/A Current price: $3 P/L: N/A N/A Q1 2021	share	0.32%	17.11M	N/A	$3	N/A	N/A Q1 2021
Biotechnology Invivyd, Inc. Portfolio share: 0.31% Portfolio value: 16.49M Avg. open price: $3.28 Current price: $2.13 P/L: -35.06% Bought +4.24% shares Q3 2022	share	0.31%	16.49M	$3.28	$2.13	-35.06%	Bought +4.24% shares Q3 2022
Biotechnology Kezar Life Sciences, Inc. Portfolio share: 0.28% Portfolio value: 15.25M Avg. open price: $6.49 Current price: $7.07 P/L: +8.98% Bought +24.78% shares Q3 2022	share	0.28%	15.25M	$6.49	$7.07	+8.98%	Bought +24.78% shares Q3 2022
Biotechnology 2seventy bio, Inc. Portfolio share: 0.28% Portfolio value: 15.15M Avg. open price: N/A Current price: $15.36 P/L: N/A N/A Q3 2022	share	0.28%	15.15M	N/A	$15.36	N/A	N/A Q3 2022
Biotechnology KalVista Pharmaceuticals, Inc. Portfolio share: 0.28% Portfolio value: 15.11M Avg. open price: $11.69 Current price: $5.17 P/L: -55.76% Bought +462.03% shares Q3 2022	share	0.28%	15.11M	$11.69	$5.17	-55.76%	Bought +462.03% shares Q3 2022
Medical Devices NeuroPace, Inc. Portfolio share: 0.28% Portfolio value: 15.04M Avg. open price: N/A Current price: $1.58 P/L: N/A N/A Q2 2021	share	0.28%	15.04M	N/A	$1.58	N/A	N/A Q2 2021
Biotechnology Verastem, Inc. Portfolio share: 0.27% Portfolio value: 14.62M Avg. open price: N/A Current price: $0.42 P/L: N/A N/A Q3 2022	share	0.27%	14.62M	N/A	$0.42	N/A	N/A Q3 2022
Medical Devices RxSight, Inc. Portfolio share: 0.27% Portfolio value: 14.43M Avg. open price: $12.67 Current price: $13.83 P/L: +9.16% Sold -13.06% shares Q3 2022	share	0.27%	14.43M	$12.67	$13.83	+9.16%	Sold -13.06% shares Q3 2022
Biotechnology Aerovate Therapeutics, Inc. Portfolio share: 0.24% Portfolio value: 13.18M Avg. open price: $15.63 Current price: $18 P/L: +15.16% Bought +66.12% shares Q3 2022	share	0.24%	13.18M	$15.63	$18	+15.16%	Bought +66.12% shares Q3 2022
BRIDGEBIO PHARMA INC Portfolio share: 0.23% Portfolio value: 12.50M Avg. open price: N/A Current price: N/A P/L: N/A N/A Q1 2022	share	0.23%	12.50M	N/A	N/A	N/A	N/A Q1 2022
BRIDGEBIO PHARMA INC Portfolio share: 0.22% Portfolio value: 11.76M Avg. open price: N/A Current price: N/A P/L: N/A N/A Q1 2022	share	0.22%	11.76M	N/A	N/A	N/A	N/A Q1 2022
Biotechnology Passage Bio, Inc. Portfolio share: 0.21% Portfolio value: 11.16M Avg. open price: $3.69 Current price: $1.16 P/L: -68.55% Bought +21.82% shares Q2 2022	share	0.21%	11.16M	$3.69	$1.16	-68.55%	Bought +21.82% shares Q2 2022
Biotechnology Mirum Pharmaceuticals, Inc. Portfolio share: 0.20% Portfolio value: 10.96M Avg. open price: $20.77 Current price: $18.33 P/L: -11.73% Bought +86.72% shares Q3 2022	share	0.20%	10.96M	$20.77	$18.33	-11.73%	Bought +86.72% shares Q3 2022
Biotechnology Ikena Oncology, Inc. Portfolio share: 0.19% Portfolio value: 10.41M Avg. open price: N/A Current price: $2.23 P/L: N/A N/A Q1 2021	share	0.19%	10.41M	N/A	$2.23	N/A	N/A Q1 2021
Biotechnology CinCor Pharma, Inc. Portfolio share: 0.19% Portfolio value: 10.31M Avg. open price: N/A Current price: $12.33 P/L: N/A N/A Q3 2022	share	0.19%	10.31M	N/A	$12.33	N/A	N/A Q3 2022
Biotechnology IMARA Inc. Portfolio share: 0.19% Portfolio value: 10.00M Avg. open price: $7.9 Current price: $3.87 P/L: -51.01% Bought +61.28% shares Q3 2021	share	0.19%	10.00M	$7.9	$3.87	-51.01%	Bought +61.28% shares Q3 2021
Biotechnology Fusion Pharmaceuticals Inc. Portfolio share: 0.18% Portfolio value: 9.70M Avg. open price: N/A Current price: $2.36 P/L: N/A N/A Q2 2020	share	0.18%	9.70M	N/A	$2.36	N/A	N/A Q2 2020
Biotechnology Gemini Therapeutics, Inc. Portfolio share: 0.18% Portfolio value: 9.55M Avg. open price: N/A Current price: $1.7 P/L: N/A Sold -0.00% shares Q3 2022	share	0.18%	9.55M	N/A	$1.7	N/A	Sold -0.00% shares Q3 2022
Biotechnology Mereo BioPharma Group plc Portfolio share: 0.17% Portfolio value: 9.13M Avg. open price: $3.07 Current price: $0.83 P/L: -72.92% Bought +9.21% shares Q3 2022	share	0.17%	9.13M	$3.07	$0.83	-72.92%	Bought +9.21% shares Q3 2022
Biotechnology X4 Pharmaceuticals, Inc. Portfolio share: 0.16% Portfolio value: 8.59M Avg. open price: $3.85 Current price: $1.29 P/L: -66.51% Bought +265.89% shares Q3 2022	share	0.16%	8.59M	$3.85	$1.29	-66.51%	Bought +265.89% shares Q3 2022
Biotechnology Cullinan Oncology, Inc. Portfolio share: 0.15% Portfolio value: 8.17M Avg. open price: N/A Current price: $11.61 P/L: N/A Sold -4.99% shares Q3 2022	share	0.15%	8.17M	N/A	$11.61	N/A	Sold -4.99% shares Q3 2022
Biotechnology Arcus Biosciences, Inc. Portfolio share: 0.15% Portfolio value: 7.92M Avg. open price: N/A Current price: $33.96 P/L: N/A N/A Q3 2022	share	0.15%	7.92M	N/A	$33.96	N/A	N/A Q3 2022
Biotechnology Ventyx Biosciences, Inc. Portfolio share: 0.15% Portfolio value: 7.85M Avg. open price: N/A Current price: $28.09 P/L: N/A Sold -82.55% shares Q3 2022	share	0.15%	7.85M	N/A	$28.09	N/A	Sold -82.55% shares Q3 2022
Biotechnology Galecto, Inc. Portfolio share: 0.14% Portfolio value: 7.73M Avg. open price: N/A Current price: $1.44 P/L: N/A N/A Q4 2020	share	0.14%	7.73M	N/A	$1.44	N/A	N/A Q4 2020
Biotechnology EyePoint Pharmaceuticals, Inc. Portfolio share: 0.14% Portfolio value: 7.68M Avg. open price: $7.87 Current price: $3.33 P/L: -57.69% Bought +353.46% shares Q3 2022	share	0.14%	7.68M	$7.87	$3.33	-57.69%	Bought +353.46% shares Q3 2022
Biotechnology NextCure, Inc. Portfolio share: 0.14% Portfolio value: 7.45M Avg. open price: N/A Current price: $1.4 P/L: N/A N/A Q2 2019	share	0.14%	7.45M	N/A	$1.4	N/A	N/A Q2 2019
Medical Devices Pulmonx Corporation Portfolio share: 0.13% Portfolio value: 7.24M Avg. open price: $44.12 Current price: $6.18 P/L: -85.99% Bought +248.00% shares Q3 2021	share	0.13%	7.24M	$44.12	$6.18	-85.99%	Bought +248.00% shares Q3 2021
Biotechnology Jounce Therapeutics, Inc. Portfolio share: 0.13% Portfolio value: 6.85M Avg. open price: $7.93 Current price: $0.91 P/L: -88.56% Bought +2.41% shares Q2 2022	share	0.13%	6.85M	$7.93	$0.91	-88.56%	Bought +2.41% shares Q2 2022
Biotechnology ORIC Pharmaceuticals, Inc. Portfolio share: 0.12% Portfolio value: 6.68M Avg. open price: N/A Current price: $4.02 P/L: N/A Sold -10.70% shares Q1 2022	share	0.12%	6.68M	N/A	$4.02	N/A	Sold -10.70% shares Q1 2022
Biotechnology Chemomab Therapeutics Ltd. Portfolio share: 0.12% Portfolio value: 6.42M Avg. open price: N/A Current price: $2.05 P/L: N/A N/A Q1 2021	share	0.12%	6.42M	N/A	$2.05	N/A	N/A Q1 2021
SPDR S&P Biotech ETF Portfolio share: 0.11% Portfolio value: 6.06M Avg. open price: $135.4 Current price: $82.88 P/L: -38.79% Sold -31.66% shares Q3 2022	share	0.11%	6.06M	$135.4	$82.88	-38.79%	Sold -31.66% shares Q3 2022
Biotechnology Vaxcyte, Inc. Portfolio share: 0.11% Portfolio value: 6M Avg. open price: $23.26 Current price: $44.33 P/L: +90.61% N/A Q3 2022	call	0.11%	6M	$23.26	$44.33	+90.61%	N/A Q3 2022
Biotechnology Synlogic, Inc. Portfolio share: 0.11% Portfolio value: 5.72M Avg. open price: $4.66 Current price: $0.74 P/L: -84.13% Bought +63.12% shares Q3 2021	share	0.11%	5.72M	$4.66	$0.74	-84.13%	Bought +63.12% shares Q3 2021
Biotechnology Corvus Pharmaceuticals, Inc. Portfolio share: 0.11% Portfolio value: 5.68M Avg. open price: $5.58 Current price: $1 P/L: -82.07% Sold -13.78% shares Q3 2021	share	0.11%	5.68M	$5.58	$1	-82.07%	Sold -13.78% shares Q3 2021
Biotechnology Cybin Inc. Portfolio share: 0.09% Portfolio value: 5.08M Avg. open price: N/A Current price: $0.35 P/L: N/A Sold -0.67% shares Q3 2022	share	0.09%	5.08M	N/A	$0.35	N/A	Sold -0.67% shares Q3 2022
Drug Manufacturers—General Eli Lilly and Company Portfolio share: 0.09% Portfolio value: 4.85M Avg. open price: $70.73 Current price: $369.29 P/L: +422.13% N/A Q3 2022	call	0.09%	4.85M	$70.73	$369.29	+422.13%	N/A Q3 2022
Biotechnology Heron Therapeutics, Inc. Portfolio share: 0.09% Portfolio value: 4.73M Avg. open price: $20.22 Current price: $2.54 P/L: -87.44% N/A Q3 2022	share	0.09%	4.73M	$20.22	$2.54	-87.44%	N/A Q3 2022
Biotechnology Scholar Rock Holding Corporation Portfolio share: 0.09% Portfolio value: 4.62M Avg. open price: N/A Current price: $7.67 P/L: N/A Sold -37.95% shares Q3 2022	share	0.09%	4.62M	N/A	$7.67	N/A	Sold -37.95% shares Q3 2022
Biotechnology Applied Therapeutics, Inc. Portfolio share: 0.07% Portfolio value: 3.95M Avg. open price: $26.08 Current price: $0.9 P/L: -96.55% N/A Q2 2022	share	0.07%	3.95M	$26.08	$0.9	-96.55%	N/A Q2 2022
Biotechnology Graybug Vision, Inc. Portfolio share: 0.07% Portfolio value: 3.91M Avg. open price: N/A Current price: $0.63 P/L: N/A Sold -6.98% shares Q1 2021	share	0.07%	3.91M	N/A	$0.63	N/A	Sold -6.98% shares Q1 2021
Biotechnology Vigil Neuroscience, Inc. Portfolio share: 0.07% Portfolio value: 3.74M Avg. open price: N/A Current price: $12 P/L: N/A N/A Q1 2022	share	0.07%	3.74M	N/A	$12	N/A	N/A Q1 2022
Biotechnology Seagen Inc. Portfolio share: 0.06% Portfolio value: 3.42M Avg. open price: $169.54 Current price: $121.22 P/L: -28.50% Sold -50.00% shares Q3 2022	call	0.06%	3.42M	$169.54	$121.22	-28.50%	Sold -50.00% shares Q3 2022
Biotechnology Achilles Therapeutics plc Portfolio share: 0.06% Portfolio value: 3.30M Avg. open price: N/A Current price: $1.71 P/L: N/A Sold -7.67% shares Q3 2022	share	0.06%	3.30M	N/A	$1.71	N/A	Sold -7.67% shares Q3 2022
Drug Manufacturers—Specialty & Generic Amneal Pharmaceuticals, Inc. Portfolio share: 0.06% Portfolio value: 3.19M Avg. open price: N/A Current price: $2.37 P/L: N/A N/A Q3 2022	share	0.06%	3.19M	N/A	$2.37	N/A	N/A Q3 2022
Biotechnology Magenta Therapeutics, Inc. Portfolio share: 0.06% Portfolio value: 3.17M Avg. open price: $10.71 Current price: $1.24 P/L: -88.42% Bought +18.91% shares Q4 2021	share	0.06%	3.17M	$10.71	$1.24	-88.42%	Bought +18.91% shares Q4 2021
Diagnostics & Research Burning Rock Biotech Limited Portfolio share: 0.06% Portfolio value: 3.06M Avg. open price: $27.01 Current price: $2.41 P/L: -91.08% Sold -7.70% shares Q3 2022	share	0.06%	3.06M	$27.01	$2.41	-91.08%	Sold -7.70% shares Q3 2022
Biotechnology Harpoon Therapeutics, Inc. Portfolio share: 0.05% Portfolio value: 2.93M Avg. open price: $14.64 Current price: $0.72 P/L: -95.08% Sold -0.45% shares Q3 2022	share	0.05%	2.93M	$14.64	$0.72	-95.08%	Sold -0.45% shares Q3 2022
Biotechnology Dyne Therapeutics, Inc. Portfolio share: 0.05% Portfolio value: 2.79M Avg. open price: N/A Current price: $11.47 P/L: N/A N/A Q3 2022	share	0.05%	2.79M	N/A	$11.47	N/A	N/A Q3 2022
Biotechnology Graphite Bio, Inc. Portfolio share: 0.05% Portfolio value: 2.68M Avg. open price: $27.11 Current price: $3.59 P/L: -86.76% Sold -45.82% shares Q2 2022	share	0.05%	2.68M	$27.11	$3.59	-86.76%	Sold -45.82% shares Q2 2022
Biotechnology Protara Therapeutics, Inc. Portfolio share: 0.05% Portfolio value: 2.45M Avg. open price: $6.92 Current price: $3.63 P/L: -47.54% Bought +84.59% shares Q4 2021	share	0.05%	2.45M	$6.92	$3.63	-47.54%	Bought +84.59% shares Q4 2021
Medical Devices Acutus Medical, Inc. Portfolio share: 0.04% Portfolio value: 2.33M Avg. open price: N/A Current price: $0.83 P/L: N/A Sold -51.65% shares Q3 2021	share	0.04%	2.33M	N/A	$0.83	N/A	Sold -51.65% shares Q3 2021
Biotechnology LogicBio Therapeutics, Inc. Portfolio share: 0.04% Portfolio value: 2.30M Avg. open price: $9.08 Current price: $2.07 P/L: -77.20% Bought +30.93% shares Q4 2020	share	0.04%	2.30M	$9.08	$2.07	-77.20%	Bought +30.93% shares Q4 2020
Biotechnology Pyxis Oncology, Inc. Portfolio share: 0.03% Portfolio value: 1.67M Avg. open price: N/A Current price: $1.29 P/L: N/A N/A Q3 2022	share	0.03%	1.67M	N/A	$1.29	N/A	N/A Q3 2022
Biotechnology OncoCyte Corporation Portfolio share: 0.03% Portfolio value: 1.37M Avg. open price: $4.74 Current price: $0.48 P/L: -89.88% Sold -33.65% shares Q3 2022	share	0.03%	1.37M	$4.74	$0.48	-89.88%	Sold -33.65% shares Q3 2022
Medical Instruments & Supplies Singular Genomics Systems, Inc. Portfolio share: 0.03% Portfolio value: 1.35M Avg. open price: $11.39 Current price: $1.92 P/L: -83.15% Sold -76.50% shares Q2 2022	share	0.03%	1.35M	$11.39	$1.92	-83.15%	Sold -76.50% shares Q2 2022
Biotechnology ESSA Pharma Inc. Portfolio share: 0.02% Portfolio value: 1.16M Avg. open price: N/A Current price: $3.47 P/L: N/A N/A Q3 2022	share	0.02%	1.16M	N/A	$3.47	N/A	N/A Q3 2022
Biotechnology Bolt Biotherapeutics, Inc. Portfolio share: 0.02% Portfolio value: 1.14M Avg. open price: N/A Current price: $1.4 P/L: N/A N/A Q3 2022	share	0.02%	1.14M	N/A	$1.4	N/A	N/A Q3 2022
Biotechnology BiomX Inc. Portfolio share: 0.02% Portfolio value: 957K Avg. open price: $5.46 Current price: $0.26 P/L: -95.32% Bought +21.61% shares Q3 2021	share	0.02%	957K	$5.46	$0.26	-95.32%	Bought +21.61% shares Q3 2021
Biotechnology Monte Rosa Therapeutics, Inc. Portfolio share: 0.02% Portfolio value: 960K Avg. open price: N/A Current price: $9.43 P/L: N/A N/A Q3 2022	share	0.02%	960K	N/A	$9.43	N/A	N/A Q3 2022
Biotechnology Aeglea BioTherapeutics, Inc. Portfolio share: 0.02% Portfolio value: 945K Avg. open price: $6.68 Current price: $0.47 P/L: -92.95% Sold -39.20% shares Q2 2022	share	0.02%	945K	$6.68	$0.47	-92.95%	Sold -39.20% shares Q2 2022
Biotechnology Vor Biopharma Inc. Portfolio share: 0.01% Portfolio value: 445K Avg. open price: N/A Current price: $4.72 P/L: N/A Sold -86.58% shares Q3 2022	share	0.01%	445K	N/A	$4.72	N/A	Sold -86.58% shares Q3 2022
Biotechnology Longboard Pharmaceuticals, Inc. Portfolio share: 0.01% Portfolio value: 422K Avg. open price: N/A Current price: $4.75 P/L: N/A Sold -62.17% shares Q2 2021	share	0.01%	422K	N/A	$4.75	N/A	Sold -62.17% shares Q2 2021
Drug Manufacturers—General Horizon Therapeutics Public Limited Company Portfolio share: 0.00% Portfolio value: 0 Avg. open price: $38.94 Current price: $98.48 P/L: +152.91% Sold -100.00% shares Q3 2022	share	0.00%	0	$38.94	$98.48	+152.91%	Sold -100.00% shares Q3 2022
Drug Manufacturers—General Gilead Sciences, Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: $59.55 Current price: $87.98 P/L: +47.75% Sold -100.00% shares Q3 2022	share	0.00%	0	$59.55	$87.98	+47.75%	Sold -100.00% shares Q3 2022
Biotechnology Theravance Biopharma, Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: $20.35 Current price: $10.89 P/L: -46.49% Sold -100.00% shares Q3 2022	share	0.00%	0	$20.35	$10.89	-46.49%	Sold -100.00% shares Q3 2022
DANAHER CORPORATION Portfolio share: 0.00% Portfolio value: 0 Avg. open price: N/A Current price: N/A P/L: N/A Sold -100.00% shares Q3 2022	share	0.00%	0	N/A	N/A	N/A	Sold -100.00% shares Q3 2022
Biotechnology Regeneron Pharmaceuticals, Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: $434.77 Current price: $755.45 P/L: +73.76% Sold -100.00% shares Q3 2022	share	0.00%	0	$434.77	$755.45	+73.76%	Sold -100.00% shares Q3 2022
Biotechnology Erasca, Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: N/A Current price: $7.28 P/L: N/A Sold -100.00% shares Q3 2022	share	0.00%	0	N/A	$7.28	N/A	Sold -100.00% shares Q3 2022
Biotechnology Aptinyx Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: $3.02 Current price: $0.25 P/L: -91.63% Sold -100.00% shares Q3 2022	share	0.00%	0	$3.02	$0.25	-91.63%	Sold -100.00% shares Q3 2022
Biotechnology Sierra Oncology, Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: $22.5 Current price: $54.99 P/L: +144.40% Sold -100.00% shares Q3 2022	share	0.00%	0	$22.5	$54.99	+144.40%	Sold -100.00% shares Q3 2022
Medical Devices Sight Sciences, Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: N/A Current price: $11.71 P/L: N/A Sold -100.00% shares Q3 2022	share	0.00%	0	N/A	$11.71	N/A	Sold -100.00% shares Q3 2022
Health Information Services Signify Health, Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: $18.15 Current price: $28.65 P/L: +57.85% Sold -100.00% shares Q3 2022	share	0.00%	0	$18.15	$28.65	+57.85%	Sold -100.00% shares Q3 2022
Medical Devices Sonendo, Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: N/A Current price: $2.63 P/L: N/A Sold -100.00% shares Q3 2022	share	0.00%	0	N/A	$2.63	N/A	Sold -100.00% shares Q3 2022
Drug Manufacturers—General Amgen Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: $139.35 Current price: $285.01 P/L: +104.53% Sold -100.00% shares Q3 2022	share	0.00%	0	$139.35	$285.01	+104.53%	Sold -100.00% shares Q3 2022
Biotechnology Novavax, Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: $181.31 Current price: $17.61 P/L: -90.29% Sold -100.00% shares Q3 2022	call	0.00%	0	$181.31	$17.61	-90.29%	Sold -100.00% shares Q3 2022
Biotechnology 9 Meters Biopharma, Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: $1.3 Current price: $1.68 P/L: +29.23% Sold -100.00% shares Q3 2022	share	0.00%	0	$1.3	$1.68	+29.23%	Sold -100.00% shares Q3 2022
Biotechnology Talaris Therapeutics, Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: N/A Current price: $1.42 P/L: N/A Sold -100.00% shares Q3 2022	share	0.00%	0	N/A	$1.42	N/A	Sold -100.00% shares Q3 2022
Biotechnology Celldex Therapeutics, Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: N/A Current price: $36.66 P/L: N/A Sold -100.00% shares Q3 2022	share	0.00%	0	N/A	$36.66	N/A	Sold -100.00% shares Q3 2022
Diagnostics & Research Natera, Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: $27.36 Current price: $40.39 P/L: +47.62% Sold -100.00% shares Q3 2022	call	0.00%	0	$27.36	$40.39	+47.62%	Sold -100.00% shares Q3 2022
NANOSTRING TECHNOLOGIES INC Portfolio share: 0.00% Portfolio value: 0 Avg. open price: N/A Current price: N/A P/L: N/A Sold -100.00% shares Q3 2022	share	0.00%	0	N/A	N/A	N/A	Sold -100.00% shares Q3 2022
Biotechnology Milestone Pharmaceuticals Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: $7.29 Current price: $4.75 P/L: -34.88% Sold -100.00% shares Q3 2022	share	0.00%	0	$7.29	$4.75	-34.88%	Sold -100.00% shares Q3 2022
Biotechnology Turning Point Therapeutics, Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: $40.7 Current price: $76.01 P/L: +86.76% Sold -100.00% shares Q3 2022	share	0.00%	0	$40.7	$76.01	+86.76%	Sold -100.00% shares Q3 2022
Biotechnology IVERIC bio, Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: $3.54 Current price: $21.89 P/L: +518.20% Sold -100.00% shares Q3 2022	share	0.00%	0	$3.54	$21.89	+518.20%	Sold -100.00% shares Q3 2022
Biotechnology Immunocore Holdings plc Portfolio share: 0.00% Portfolio value: 0 Avg. open price: $29.9 Current price: $58.07 P/L: +94.21% Sold -100.00% shares Q3 2022	share	0.00%	0	$29.9	$58.07	+94.21%	Sold -100.00% shares Q3 2022
Biotechnology CytomX Therapeutics, Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: $5.31 Current price: $1.71 P/L: -67.83% Sold -100.00% shares Q3 2022	share	0.00%	0	$5.31	$1.71	-67.83%	Sold -100.00% shares Q3 2022
Biotechnology VistaGen Therapeutics, Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: $2.04 Current price: $0.12 P/L: -93.90% Sold -100.00% shares Q3 2022	share	0.00%	0	$2.04	$0.12	-93.90%	Sold -100.00% shares Q3 2022
Diagnostics & Research Guardant Health, Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: $125.95 Current price: $51.95 P/L: -58.75% Sold -100.00% shares Q3 2022	call	0.00%	0	$125.95	$51.95	-58.75%	Sold -100.00% shares Q3 2022
Biotechnology AbCellera Biologics Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: N/A Current price: $11.91 P/L: N/A Sold -100.00% shares Q3 2022	call	0.00%	0	N/A	$11.91	N/A	Sold -100.00% shares Q3 2022
Biotechnology Global Blood Therapeutics, Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: $35.08 Current price: $68.49 P/L: +95.22% Sold -100.00% shares Q3 2022	share	0.00%	0	$35.08	$68.49	+95.22%	Sold -100.00% shares Q3 2022

Showing TOP 158 ORBIMED ADVISORS's 13F holdings.

Frequently Asked Questions (FAQ)

What is the biggest position of ORBIMED ADVISORS LLC?

The biggest position of the ORBIMED ADVISORS LLC is Sinovac Biotech Ltd. (SVA) with 6.32% portfolio share worth of 340.5M US dollars.

Top 5 ORBIMED ADVISORS's holdings represent 18.6% of the portfolio:

Sinovac Biotech Ltd. (SVA) – 6.32%
Bristol-Myers Squibb Company (BMY) – 3.41%
Humana Inc. (HUM) – 3.14%
SpringWorks Therapeutics, Inc. (SWTX) – 2.93%
Boston Scientific Corporation (BSX) – 2.8%

Who is the portfolio manager of ORBIMED ADVISORS LLC?

The portfolio manager of the ORBIMED ADVISORS LLC is .

What is the total asset value of the ORBIMED ADVISORS LLC portfolio?

ORBIMED ADVISORS LLC total asset value (portfolio value) is 5.39B US dollars.

Who is ?

is the portfolio manager of the ORBIMED ADVISORS LLC.

What is (ORBIMED ADVISORS LLC) fund performance?

ORBIMED ADVISORS's quarterly performance is +4.14%, annualy -33.80%. In the past 3 years, the value of 's portfolio has decreased by -45%. In the past 5 years, the value of the portfolio has increased by +1%.

What is the ORBIMED ADVISORS LLC CIK?

ORBIMED ADVISORS's Central Index Key is 0001055951 .

ORBIMED ADVISORS LLC Holdings

ORBIMED ADVISORS LLC portfolio value:

ORBIMED ADVISORS LLC quarter portfolio value change:

ORBIMED ADVISORS LLC 1 year portfolio value change:

ORBIMED ADVISORS LLC 3 years portfolio value change:

ORBIMED ADVISORS LLC 5 years portfolio value change: