TEKLA CAPITAL MANAGEMENT LLC Holdings

TEKLA CAPITAL MANAGEMENT LLC is an investment fund managing more than 2.44B US dollars. The largest holdings include UnitedHealth Group Incorporated, Johnson & Johnson and Amgen. In Q3 2022 the fund bought assets of total value of 260.62M US dollars and sold assets of total value of 339.28M US dollars.

$2.44B

portfolio value

-2.06%

quarter

-16.23%

1 year

+22.15%

3 years

+17.85%

5 years

TEKLA CAPITAL MANAGEMENT LLC portfolio changes

Portfolio changes (number of shares)
Period	Buy	Sel
Q1 2016	61322000	181657000
Q2 2016	225262000	204042000
Q3 2016	328516000	152989000
Q4 2016	95928000	195593000
Q1 2017	267392000	106105000
Q2 2017	194515000	120751000
Q3 2017	203521000	111676000
Q4 2017	201151000	328887000
Q1 2018	320378000	327610000
Q2 2018	204296000	123648000
Q3 2018	259484000	139673000
Q4 2018	-17400000	253937000
Q1 2019	297188000	159691000
Q2 2019	109020000	103787000
Q3 2019	82908000	216596000
Q4 2019	430860000	19927000
Q1 2020	37631000	385847000
Q2 2020	343002000	25276000
Q3 2020	352093000	296951000
Q4 2020	561530000	441833000
Q1 2021	458289000	385570000
Q2 2021	273916000	107693000
Q3 2021	416413000	319824000
Q4 2021	286370000	302691000
Q1 2022	177437000	304677000
Q2 2022	81247000	275457000
Q3 2022	260624000	339283000

TEKLA CAPITAL MANAGEMENT LLC 13F holdings

Stock	Position type	Portfolio share	Portfolio value	Avg. open price	Current price	P/L	Last change
Healthcare Plans UnitedHealth Group Incorporated Portfolio share: 5.67% Portfolio value: 138.40M Avg. open price: $259.3 Current price: $536.16 P/L: +106.77% Sold -14.23% shares Q3 2022	share	5.67%	138.40M	$259.3	$536.16	+106.77%	Sold -14.23% shares Q3 2022
Drug Manufacturers—General Johnson & Johnson Portfolio share: 5.24% Portfolio value: 128.03M Avg. open price: $128.84 Current price: $178.88 P/L: +38.84% Bought +51.70% shares Q3 2022	share	5.24%	128.03M	$128.84	$178.88	+38.84%	Bought +51.70% shares Q3 2022
Drug Manufacturers—General Amgen Inc. Portfolio share: 4.79% Portfolio value: 116.95M Avg. open price: $163.36 Current price: $285.51 P/L: +74.77% Sold -5.39% shares Q3 2022	share	4.79%	116.95M	$163.36	$285.51	+74.77%	Sold -5.39% shares Q3 2022
Drug Manufacturers—General Gilead Sciences, Inc. Portfolio share: 4.10% Portfolio value: 100.07M Avg. open price: $63.28 Current price: $89.03 P/L: +40.68% Sold -1.73% shares Q3 2022	share	4.10%	100.07M	$63.28	$89.03	+40.68%	Sold -1.73% shares Q3 2022
Biotechnology Vertex Pharmaceuticals Incorporated Portfolio share: 3.71% Portfolio value: 90.74M Avg. open price: $221.03 Current price: $321.37 P/L: +45.40% Sold -13.24% shares Q3 2022	share	3.71%	90.74M	$221.03	$321.37	+45.40%	Sold -13.24% shares Q3 2022
Drug Manufacturers—General Eli Lilly and Company Portfolio share: 3.18% Portfolio value: 77.79M Avg. open price: $104.5 Current price: $374.76 P/L: +258.61% Bought +36.36% shares Q3 2022	share	3.18%	77.79M	$104.5	$374.76	+258.61%	Bought +36.36% shares Q3 2022
Medical Devices Abbott Laboratories Portfolio share: 3.13% Portfolio value: 76.54M Avg. open price: $71.33 Current price: $108.09 P/L: +51.53% Bought +26.11% shares Q3 2022	share	3.13%	76.54M	$71.33	$108.09	+51.53%	Bought +26.11% shares Q3 2022
Biotechnology Regeneron Pharmaceuticals, Inc. Portfolio share: 3.08% Portfolio value: 75.13M Avg. open price: $418.02 Current price: $766.39 P/L: +83.34% Sold -23.66% shares Q3 2022	share	3.08%	75.13M	$418.02	$766.39	+83.34%	Sold -23.66% shares Q3 2022
Drug Manufacturers—General AbbVie Inc. Portfolio share: 2.89% Portfolio value: 70.70M Avg. open price: $80.27 Current price: $163.66 P/L: +103.89% Sold -7.06% shares Q3 2022	share	2.89%	70.70M	$80.27	$163.66	+103.89%	Sold -7.06% shares Q3 2022
Drug Manufacturers—General AstraZeneca PLC Portfolio share: 2.86% Portfolio value: 69.82M Avg. open price: $47.55 Current price: $68.47 P/L: +44.00% Bought +13.20% shares Q3 2022	share	2.86%	69.82M	$47.55	$68.47	+44.00%	Bought +13.20% shares Q3 2022
Drug Manufacturers—General Bristol-Myers Squibb Company Portfolio share: 2.56% Portfolio value: 62.52M Avg. open price: $57.68 Current price: $81.13 P/L: +40.67% Bought +12.36% shares Q3 2022	share	2.56%	62.52M	$57.68	$81.13	+40.67%	Bought +12.36% shares Q3 2022
Healthcare Plans Cigna Corp. Portfolio share: 2.39% Portfolio value: 58.47M Avg. open price: $194.01 Current price: $327.2 P/L: +68.65% Bought +21.74% shares Q3 2022	share	2.39%	58.47M	$194.01	$327.2	+68.65%	Bought +21.74% shares Q3 2022
Diagnostics & Research Illumina, Inc. Portfolio share: 2.30% Portfolio value: 56.27M Avg. open price: $260.26 Current price: $218.76 P/L: -15.95% Bought +50.45% shares Q3 2022	share	2.30%	56.27M	$260.26	$218.76	-15.95%	Bought +50.45% shares Q3 2022
Healthcare Plans Humana Inc. Portfolio share: 2.24% Portfolio value: 54.82M Avg. open price: $336.47 Current price: $546.78 P/L: +62.51% Bought +77.14% shares Q3 2022	share	2.24%	54.82M	$336.47	$546.78	+62.51%	Bought +77.14% shares Q3 2022
Drug Manufacturers—General Pfizer Inc. Portfolio share: 2.03% Portfolio value: 49.54M Avg. open price: $34.25 Current price: $50.91 P/L: +48.64% Sold -3.40% shares Q2 2022	share	2.03%	49.54M	$34.25	$50.91	+48.64%	Sold -3.40% shares Q2 2022
Drug Manufacturers—General Merck & Co., Inc. Portfolio share: 1.95% Portfolio value: 47.54M Avg. open price: $60.35 Current price: $110.04 P/L: +82.35% Sold -4.08% shares Q2 2022	share	1.95%	47.54M	$60.35	$110.04	+82.35%	Sold -4.08% shares Q2 2022
Diagnostics & Research Thermo Fisher Scientific Inc. Portfolio share: 1.95% Portfolio value: 47.52M Avg. open price: $263.36 Current price: $563 P/L: +113.78% Sold -4.00% shares Q3 2022	share	1.95%	47.52M	$263.36	$563	+113.78%	Sold -4.00% shares Q3 2022
Drug Manufacturers—General Horizon Therapeutics Public Limited Company Portfolio share: 1.86% Portfolio value: 45.44M Avg. open price: $63.18 Current price: $104.85 P/L: +65.96% Sold -16.18% shares Q3 2022	share	1.86%	45.44M	$63.18	$104.85	+65.96%	Sold -16.18% shares Q3 2022
Healthcare Plans Molina Healthcare, Inc. Portfolio share: 1.61% Portfolio value: 39.42M Avg. open price: $128.63 Current price: $334.17 P/L: +159.79% Bought +13.75% shares Q3 2022	share	1.61%	39.42M	$128.63	$334.17	+159.79%	Bought +13.75% shares Q3 2022
Medical Devices Stryker Corporation Portfolio share: 1.60% Portfolio value: 39.19M Avg. open price: $193.91 Current price: $243.11 P/L: +25.37% Sold -14.25% shares Q3 2022	share	1.60%	39.19M	$193.91	$243.11	+25.37%	Sold -14.25% shares Q3 2022
Drug Manufacturers—General Biogen Inc. Portfolio share: 1.59% Portfolio value: 38.83M Avg. open price: $278.29 Current price: $298.9 P/L: +7.41% Bought +7.23% shares Q3 2022	share	1.59%	38.83M	$278.29	$298.9	+7.41%	Bought +7.23% shares Q3 2022
Biotechnology Moderna, Inc. Portfolio share: 1.52% Portfolio value: 37.24M Avg. open price: $116.62 Current price: $182.35 P/L: +56.36% Sold -4.14% shares Q3 2022	share	1.52%	37.24M	$116.62	$182.35	+56.36%	Sold -4.14% shares Q3 2022
Diagnostics & Research Danaher Corporation Portfolio share: 1.32% Portfolio value: 32.17M Avg. open price: $167.76 Current price: $274.23 P/L: +63.47% Sold -17.04% shares Q2 2022	share	1.32%	32.17M	$167.76	$274.23	+63.47%	Sold -17.04% shares Q2 2022
Medical Devices Boston Scientific Corporation Portfolio share: 1.26% Portfolio value: 30.79M Avg. open price: $38.42 Current price: $46.6 P/L: +21.29% Bought +39.66% shares Q2 2022	share	1.26%	30.79M	$38.42	$46.6	+21.29%	Bought +39.66% shares Q2 2022
Biotechnology Alnylam Pharmaceuticals, Inc. Portfolio share: 1.17% Portfolio value: 28.66M Avg. open price: $110.01 Current price: $234.4 P/L: +113.08% Bought +11.53% shares Q3 2022	share	1.17%	28.66M	$110.01	$234.4	+113.08%	Bought +11.53% shares Q3 2022
Medical Devices Zimmer Biomet Holdings, Inc. Portfolio share: 1.11% Portfolio value: 27.06M Avg. open price: $115.53 Current price: $122.97 P/L: +6.44% Bought +82.24% shares Q3 2022	share	1.11%	27.06M	$115.53	$122.97	+6.44%	Bought +82.24% shares Q3 2022
Biotechnology argenx SE Portfolio share: 1.11% Portfolio value: 27.05M Avg. open price: $282.99 Current price: $402.31 P/L: +42.16% Bought +99.28% shares Q3 2022	share	1.11%	27.05M	$282.99	$402.31	+42.16%	Bought +99.28% shares Q3 2022
Medical Devices Medtronic plc Portfolio share: 1.08% Portfolio value: 26.33M Avg. open price: $81.66 Current price: $79.62 P/L: -2.50% Sold -25.04% shares Q2 2022	share	1.08%	26.33M	$81.66	$79.62	-2.50%	Sold -25.04% shares Q2 2022
Biotechnology Rallybio Corporation Portfolio share: 1.03% Portfolio value: 25.19M Avg. open price: N/A Current price: $5.78 P/L: N/A Sold -9.85% shares Q3 2022	share	1.03%	25.19M	N/A	$5.78	N/A	Sold -9.85% shares Q3 2022
Biotechnology United Therapeutics Corporation Portfolio share: 1.01% Portfolio value: 24.57M Avg. open price: $174.66 Current price: $278.55 P/L: +59.48% Bought +62.56% shares Q3 2022	share	1.01%	24.57M	$174.66	$278.55	+59.48%	Bought +62.56% shares Q3 2022
Biotechnology Jazz Pharmaceuticals plc Portfolio share: 1.00% Portfolio value: 24.36M Avg. open price: $146.65 Current price: $157.25 P/L: +7.23% Bought +8.86% shares Q3 2022	share	1.00%	24.36M	$146.65	$157.25	+7.23%	Bought +8.86% shares Q3 2022
Medical Care Facilities HCA Healthcare, Inc. Portfolio share: 0.94% Portfolio value: 22.84M Avg. open price: $104.46 Current price: $239.03 P/L: +128.82% Bought +11.02% shares Q1 2022	share	0.94%	22.84M	$104.46	$239.03	+128.82%	Bought +11.02% shares Q1 2022
Drug Manufacturers—Specialty & Generic Zoetis Inc. Portfolio share: 0.83% Portfolio value: 20.30M Avg. open price: $121.39 Current price: $157.42 P/L: +29.68% Sold -6.68% shares Q3 2022	share	0.83%	20.30M	$121.39	$157.42	+29.68%	Sold -6.68% shares Q3 2022
Medical Devices DexCom, Inc. Portfolio share: 0.81% Portfolio value: 19.79M Avg. open price: $184.58 Current price: $118.11 P/L: -36.01% Bought +89.18% shares Q3 2022	share	0.81%	19.79M	$184.58	$118.11	-36.01%	Bought +89.18% shares Q3 2022
Medical Instruments & Supplies Intuitive Surgical, Inc. Portfolio share: 0.80% Portfolio value: 19.56M Avg. open price: $198.38 Current price: $272.25 P/L: +37.24% Sold -1.67% shares Q3 2022	share	0.80%	19.56M	$198.38	$272.25	+37.24%	Sold -1.67% shares Q3 2022
Diagnostics & Research Guardant Health, Inc. Portfolio share: 0.76% Portfolio value: 18.63M Avg. open price: $110.06 Current price: $53.81 P/L: -51.11% Sold -1.54% shares Q3 2022	share	0.76%	18.63M	$110.06	$53.81	-51.11%	Sold -1.54% shares Q3 2022
Biotechnology Sarepta Therapeutics, Inc. Portfolio share: 0.75% Portfolio value: 18.34M Avg. open price: $73.47 Current price: $126.25 P/L: +71.85% Sold -21.78% shares Q3 2022	share	0.75%	18.34M	$73.47	$126.25	+71.85%	Sold -21.78% shares Q3 2022
Biotechnology Apellis Pharmaceuticals, Inc. Portfolio share: 0.74% Portfolio value: 18.17M Avg. open price: $43.75 Current price: $50.63 P/L: +15.72% Sold -14.77% shares Q3 2022	share	0.74%	18.17M	$43.75	$50.63	+15.72%	Sold -14.77% shares Q3 2022
Drug Manufacturers—Specialty & Generic Neurocrine Biosciences, Inc. Portfolio share: 0.73% Portfolio value: 17.85M Avg. open price: $58.18 Current price: $126.81 P/L: +117.95% Bought +34.91% shares Q2 2022	share	0.73%	17.85M	$58.18	$126.81	+117.95%	Bought +34.91% shares Q2 2022
Diagnostics & Research IDEXX Laboratories, Inc. Portfolio share: 0.72% Portfolio value: 17.66M Avg. open price: $434.04 Current price: $435.3 P/L: +0.29% Bought +2.45% shares Q3 2022	share	0.72%	17.66M	$434.04	$435.3	+0.29%	Bought +2.45% shares Q3 2022
Drug Manufacturers—Specialty & Generic Lantheus Holdings, Inc. Portfolio share: 0.66% Portfolio value: 16.11M Avg. open price: $66.03 Current price: $61.27 P/L: -7.21% Bought +80.33% shares Q3 2022	share	0.66%	16.11M	$66.03	$61.27	-7.21%	Bought +80.33% shares Q3 2022
Diagnostics & Research Charles River Laboratories International, Inc. Portfolio share: 0.59% Portfolio value: 14.30M Avg. open price: $231.17 Current price: $222.66 P/L: -3.68% Bought +51.74% shares Q3 2022	share	0.59%	14.30M	$231.17	$222.66	-3.68%	Bought +51.74% shares Q3 2022
Medical Devices Edwards Lifesciences Corporation Portfolio share: 0.58% Portfolio value: 14.16M Avg. open price: $63.94 Current price: $76.55 P/L: +19.72% Sold -3.27% shares Q2 2022	share	0.58%	14.16M	$63.94	$76.55	+19.72%	Sold -3.27% shares Q2 2022
Medical Instruments & Supplies ResMed Inc. Portfolio share: 0.54% Portfolio value: 13.25M Avg. open price: $192.47 Current price: $232.9 P/L: +21.01% Sold -14.51% shares Q3 2022	share	0.54%	13.25M	$192.47	$232.9	+21.01%	Sold -14.51% shares Q3 2022
Biotechnology Novo Nordisk A/S Portfolio share: 0.53% Portfolio value: 13.00M Avg. open price: $50.12 Current price: $126.9 P/L: +153.19% Sold -14.98% shares Q2 2022	share	0.53%	13.00M	$50.12	$126.9	+153.19%	Sold -14.98% shares Q2 2022
Biotechnology BioNTech SE Portfolio share: 0.52% Portfolio value: 12.81M Avg. open price: $240.31 Current price: $169.74 P/L: -29.37% Bought +5.32% shares Q1 2022	share	0.52%	12.81M	$240.31	$169.74	-29.37%	Bought +5.32% shares Q1 2022
Biotechnology BioMarin Pharmaceutical Inc. Portfolio share: 0.52% Portfolio value: 12.79M Avg. open price: $93.03 Current price: $105.56 P/L: +13.47% Bought +17.92% shares Q3 2022	share	0.52%	12.79M	$93.03	$105.56	+13.47%	Bought +17.92% shares Q3 2022
Diagnostics & Research IQVIA Holdings Inc. Portfolio share: 0.50% Portfolio value: 12.28M Avg. open price: $178.26 Current price: $217.73 P/L: +22.14% Sold -19.56% shares Q3 2022	share	0.50%	12.28M	$178.26	$217.73	+22.14%	Sold -19.56% shares Q3 2022
Healthcare Plans CVS Health Corporation Portfolio share: 0.48% Portfolio value: 11.80M Avg. open price: $65.3 Current price: $102.58 P/L: +57.09% Sold -16.04% shares Q2 2022	share	0.48%	11.80M	$65.3	$102.58	+57.09%	Sold -16.04% shares Q2 2022
SPDR S&P Biotech ETF Portfolio share: 0.48% Portfolio value: 11.71M Avg. open price: $82.3 Current price: $85.66 P/L: +4.08% Sold -29.39% shares Q3 2022	share	0.48%	11.71M	$82.3	$85.66	+4.08%	Sold -29.39% shares Q3 2022
Medical Distribution McKesson Corporation Portfolio share: 0.47% Portfolio value: 11.43M Avg. open price: $151.65 Current price: $386.85 P/L: +155.10% Sold -79.06% shares Q3 2022	share	0.47%	11.43M	$151.65	$386.85	+155.10%	Sold -79.06% shares Q3 2022
Medical Care Facilities Acadia Healthcare Company, Inc. Portfolio share: 0.45% Portfolio value: 11.03M Avg. open price: $44.66 Current price: $87.44 P/L: +95.80% Bought +95.26% shares Q3 2022	share	0.45%	11.03M	$44.66	$87.44	+95.80%	Bought +95.26% shares Q3 2022
Biotechnology Biohaven Ltd. Portfolio share: 0.43% Portfolio value: 10.60M Avg. open price: $54.44 Current price: $16.74 P/L: -69.25% Sold -22.71% shares Q4 2021	share	0.43%	10.60M	$54.44	$16.74	-69.25%	Sold -22.71% shares Q4 2021
Drug Manufacturers—General Novartis AG Portfolio share: 0.42% Portfolio value: 10.35M Avg. open price: $64.91 Current price: $89.99 P/L: +38.64% Sold -5.74% shares Q1 2021	share	0.42%	10.35M	$64.91	$89.99	+38.64%	Sold -5.74% shares Q1 2021
Biotechnology uniQure N.V. Portfolio share: 0.40% Portfolio value: 9.78M Avg. open price: $30.54 Current price: $26.03 P/L: -14.77% Bought +120.12% shares Q4 2021	share	0.40%	9.78M	$30.54	$26.03	-14.77%	Bought +120.12% shares Q4 2021
Diagnostics & Research Laboratory Corporation of America Holdings Portfolio share: 0.37% Portfolio value: 9.04M Avg. open price: $187.55 Current price: $241.57 P/L: +28.80% Sold -53.37% shares Q4 2021	share	0.37%	9.04M	$187.55	$241.57	+28.80%	Sold -53.37% shares Q4 2021
REIT—Healthcare Facilities Omega Healthcare Investors, Inc. Portfolio share: 0.37% Portfolio value: 9.03M Avg. open price: $25.06 Current price: $30.23 P/L: +20.61% Bought +7.60% shares Q1 2020	share	0.37%	9.03M	$25.06	$30.23	+20.61%	Bought +7.60% shares Q1 2020
Biotechnology Intellia Therapeutics, Inc. Portfolio share: 0.35% Portfolio value: 8.63M Avg. open price: $42.2 Current price: $46.12 P/L: +9.28% Bought +165.16% shares Q3 2022	share	0.35%	8.63M	$42.2	$46.12	+9.28%	Bought +165.16% shares Q3 2022
Biotechnology Mirati Therapeutics, Inc. Portfolio share: 0.35% Portfolio value: 8.54M Avg. open price: $95.65 Current price: $96.25 P/L: +0.63% Bought +46.08% shares Q3 2022	share	0.35%	8.54M	$95.65	$96.25	+0.63%	Bought +46.08% shares Q3 2022
Drug Manufacturers—Specialty & Generic Intra-Cellular Therapies, Inc. Portfolio share: 0.33% Portfolio value: 8.02M Avg. open price: $28.67 Current price: $54.08 P/L: +88.64% Sold -29.19% shares Q3 2022	share	0.33%	8.02M	$28.67	$54.08	+88.64%	Sold -29.19% shares Q3 2022
Medical Care Facilities Addus HomeCare Corporation Portfolio share: 0.33% Portfolio value: 7.96M Avg. open price: $93.82 Current price: $112.55 P/L: +19.96% Bought +54.20% shares Q3 2021	share	0.33%	7.96M	$93.82	$112.55	+19.96%	Bought +54.20% shares Q3 2021
Health Information Services HealthEquity, Inc. Portfolio share: 0.30% Portfolio value: 7.40M Avg. open price: $67.44 Current price: $65.52 P/L: -2.85% Sold -4.42% shares Q3 2022	share	0.30%	7.40M	$67.44	$65.52	-2.85%	Sold -4.42% shares Q3 2022
Biotechnology Seagen Inc. Portfolio share: 0.30% Portfolio value: 7.30M Avg. open price: $124.14 Current price: $122.41 P/L: -1.39% Sold -72.65% shares Q3 2022	share	0.30%	7.30M	$124.14	$122.41	-1.39%	Sold -72.65% shares Q3 2022
Biotechnology Ascendis Pharma A/S Portfolio share: 0.29% Portfolio value: 7M Avg. open price: $114.97 Current price: $125.39 P/L: +9.06% Sold -55.87% shares Q3 2021	share	0.29%	7M	$114.97	$125.39	+9.06%	Sold -55.87% shares Q3 2021
Drug Manufacturers—Specialty & Generic Alkermes plc Portfolio share: 0.28% Portfolio value: 6.91M Avg. open price: $43.44 Current price: $26.09 P/L: -39.94% Bought +62.85% shares Q3 2022	share	0.28%	6.91M	$43.44	$26.09	-39.94%	Bought +62.85% shares Q3 2022
REIT—Healthcare Facilities LTC Properties, Inc. Portfolio share: 0.28% Portfolio value: 6.82M Avg. open price: $39.07 Current price: $39.74 P/L: +1.70% Bought +10.04% shares Q1 2020	share	0.28%	6.82M	$39.07	$39.74	+1.70%	Bought +10.04% shares Q1 2020
Biotechnology Denali Therapeutics Inc. Portfolio share: 0.28% Portfolio value: 6.82M Avg. open price: $81.2 Current price: $32.63 P/L: -59.81% Bought +48.20% shares Q3 2021	share	0.28%	6.82M	$81.2	$32.63	-59.81%	Bought +48.20% shares Q3 2021
REIT—Healthcare Facilities Sabra Health Care REIT, Inc. Portfolio share: 0.27% Portfolio value: 6.7M Avg. open price: $16 Current price: $13.07 P/L: -18.34% Bought +9.53% shares Q1 2020	share	0.27%	6.7M	$16	$13.07	-18.34%	Bought +9.53% shares Q1 2020
Healthcare Plans Elevance Health Inc. Portfolio share: 0.27% Portfolio value: 6.65M Avg. open price: N/A Current price: $523.6 P/L: N/A Sold -86.41% shares Q3 2021	share	0.27%	6.65M	N/A	$523.6	N/A	Sold -86.41% shares Q3 2021
Health Information Services Allscripts Healthcare Solutions, Inc. Portfolio share: 0.27% Portfolio value: 6.52M Avg. open price: N/A Current price: $19.06 P/L: N/A N/A Q3 2022	share	0.27%	6.52M	N/A	$19.06	N/A	N/A Q3 2022
Biotechnology Travere Therapeutics, Inc. Portfolio share: 0.25% Portfolio value: 6.10M Avg. open price: $30.31 Current price: $20.08 P/L: -33.75% Bought +16.35% shares Q1 2022	share	0.25%	6.10M	$30.31	$20.08	-33.75%	Bought +16.35% shares Q1 2022
Biotechnology Caribou Biosciences, Inc. Portfolio share: 0.24% Portfolio value: 5.98M Avg. open price: N/A Current price: $9.61 P/L: N/A Sold -18.91% shares Q3 2022	share	0.24%	5.98M	N/A	$9.61	N/A	Sold -18.91% shares Q3 2022
Medical Distribution Owens & Minor, Inc. Portfolio share: 0.22% Portfolio value: 5.42M Avg. open price: $42.33 Current price: $21.03 P/L: -50.32% Sold -21.88% shares Q3 2022	share	0.22%	5.42M	$42.33	$21.03	-50.32%	Sold -21.88% shares Q3 2022
Biotechnology Karuna Therapeutics, Inc. Portfolio share: 0.22% Portfolio value: 5.31M Avg. open price: $92.36 Current price: $236.82 P/L: +156.42% Sold -70.13% shares Q3 2022	share	0.22%	5.31M	$92.36	$236.82	+156.42%	Sold -70.13% shares Q3 2022
Biotechnology G1 Therapeutics, Inc. Portfolio share: 0.22% Portfolio value: 5.29M Avg. open price: $24.06 Current price: $6.16 P/L: -74.40% Sold -32.11% shares Q4 2021	share	0.22%	5.29M	$24.06	$6.16	-74.40%	Sold -32.11% shares Q4 2021
Diagnostics & Research Agilent Technologies, Inc. Portfolio share: 0.21% Portfolio value: 5.25M Avg. open price: $123.65 Current price: $155.67 P/L: +25.89% Sold -35.39% shares Q2 2022	share	0.21%	5.25M	$123.65	$155.67	+25.89%	Sold -35.39% shares Q2 2022
Biotechnology Xencor, Inc. Portfolio share: 0.21% Portfolio value: 5.20M Avg. open price: $32.39 Current price: $30.86 P/L: -4.71% Sold -15.47% shares Q3 2022	share	0.21%	5.20M	$32.39	$30.86	-4.71%	Sold -15.47% shares Q3 2022
Biotechnology Arrowhead Pharmaceuticals, Inc. Portfolio share: 0.21% Portfolio value: 5.18M Avg. open price: $50.95 Current price: $33.93 P/L: -33.40% Bought +16.37% shares Q2 2022	share	0.21%	5.18M	$50.95	$33.93	-33.40%	Bought +16.37% shares Q2 2022
Biotechnology Cerevel Therapeutics Holdings, Inc. Portfolio share: 0.20% Portfolio value: 4.98M Avg. open price: $28.92 Current price: $29.64 P/L: +2.48% Bought +100.16% shares Q3 2022	share	0.20%	4.98M	$28.92	$29.64	+2.48%	Bought +100.16% shares Q3 2022
REIT—Healthcare Facilities Medical Properties Trust, Inc. Portfolio share: 0.20% Portfolio value: 4.88M Avg. open price: $14.84 Current price: $13.01 P/L: -12.34% Bought +10.01% shares Q1 2020	share	0.20%	4.88M	$14.84	$13.01	-12.34%	Bought +10.01% shares Q1 2020
Drug Manufacturers—General Sanofi Portfolio share: 0.19% Portfolio value: 4.69M Avg. open price: $47.21 Current price: $45.01 P/L: -4.66% Sold -19.44% shares Q4 2021	share	0.19%	4.69M	$47.21	$45.01	-4.66%	Sold -19.44% shares Q4 2021
Biotechnology Design Therapeutics, Inc. Portfolio share: 0.19% Portfolio value: 4.69M Avg. open price: $14.43 Current price: $14 P/L: -2.98% Bought +158.75% shares Q3 2022	share	0.19%	4.69M	$14.43	$14	-2.98%	Bought +158.75% shares Q3 2022
VectivBio Holding AG Portfolio share: 0.19% Portfolio value: 4.53M Avg. open price: N/A Current price: N/A P/L: N/A Bought +421.73% shares Q3 2021	share	0.19%	4.53M	N/A	N/A	N/A	Bought +421.73% shares Q3 2021
Biotechnology BioCryst Pharmaceuticals, Inc. Portfolio share: 0.18% Portfolio value: 4.40M Avg. open price: $9.81 Current price: $12.79 P/L: +30.33% Bought +26.00% shares Q3 2022	share	0.18%	4.40M	$9.81	$12.79	+30.33%	Bought +26.00% shares Q3 2022
Medical Devices Smith & Nephew plc Portfolio share: 0.17% Portfolio value: 4.21M Avg. open price: $37.74 Current price: $27.18 P/L: -27.98% Bought +68.77% shares Q3 2021	share	0.17%	4.21M	$37.74	$27.18	-27.98%	Bought +68.77% shares Q3 2021
Biotechnology ChemoCentryx, Inc. Portfolio share: 0.17% Portfolio value: 4.04M Avg. open price: N/A Current price: $51.99 P/L: N/A Sold -45.86% shares Q2 2021	share	0.17%	4.04M	N/A	$51.99	N/A	Sold -45.86% shares Q2 2021
Medical Devices Align Technology, Inc. Portfolio share: 0.16% Portfolio value: 3.91M Avg. open price: $494.34 Current price: $198.41 P/L: -59.86% Bought +153.30% shares Q1 2022	share	0.16%	3.91M	$494.34	$198.41	-59.86%	Bought +153.30% shares Q1 2022
Biotechnology Ionis Pharmaceuticals, Inc. Portfolio share: 0.16% Portfolio value: 3.88M Avg. open price: $54.66 Current price: $40.32 P/L: -26.23% Sold -50.00% shares Q3 2022	share	0.16%	3.88M	$54.66	$40.32	-26.23%	Sold -50.00% shares Q3 2022
Biotechnology Arvinas, Inc. Portfolio share: 0.16% Portfolio value: 3.82M Avg. open price: $84.93 Current price: $41.39 P/L: -51.27% Bought +17.07% shares Q1 2021	share	0.16%	3.82M	$84.93	$41.39	-51.27%	Bought +17.07% shares Q1 2021
Health Information Services R1 RCM Inc. Portfolio share: 0.15% Portfolio value: 3.75M Avg. open price: $24.68 Current price: $9.56 P/L: -61.26% N/A Q2 2022	share	0.15%	3.75M	$24.68	$9.56	-61.26%	N/A Q2 2022
Drug Manufacturers—Specialty & Generic Teva Pharmaceutical Industries Limited Portfolio share: 0.15% Portfolio value: 3.70M Avg. open price: $32.26 Current price: $8.66 P/L: -73.15% Sold -24.36% shares Q4 2021	share	0.15%	3.70M	$32.26	$8.66	-73.15%	Sold -24.36% shares Q4 2021
REIT—Healthcare Facilities Healthcare Realty Trust Incorporated Portfolio share: 0.15% Portfolio value: 3.64M Avg. open price: $30.79 Current price: $20.43 P/L: -33.66% N/A Q3 2022	share	0.15%	3.64M	$30.79	$20.43	-33.66%	N/A Q3 2022
Biotechnology Cytokinetics, Incorporated Portfolio share: 0.15% Portfolio value: 3.64M Avg. open price: $45.6 Current price: $40.49 P/L: -11.21% Sold -37.33% shares Q3 2022	share	0.15%	3.64M	$45.6	$40.49	-11.21%	Sold -37.33% shares Q3 2022
Biotechnology CRISPR Therapeutics AG Portfolio share: 0.15% Portfolio value: 3.59M Avg. open price: $117.85 Current price: $54.5 P/L: -53.76% Sold -66.07% shares Q4 2021	share	0.15%	3.59M	$117.85	$54.5	-53.76%	Sold -66.07% shares Q4 2021
Health Care Select Sector SPDR Fund Portfolio share: 0.14% Portfolio value: 3.51M Avg. open price: $115.88 Current price: $139.78 P/L: +20.63% Sold -74.37% shares Q3 2022	share	0.14%	3.51M	$115.88	$139.78	+20.63%	Sold -74.37% shares Q3 2022
REIT—Healthcare Facilities Healthpeak Properties, Inc. Portfolio share: 0.14% Portfolio value: 3.44M Avg. open price: $31.59 Current price: $26.18 P/L: -17.12% Bought +17.00% shares Q1 2020	share	0.14%	3.44M	$31.59	$26.18	-17.12%	Bought +17.00% shares Q1 2020
Biotechnology Merus N.V. Portfolio share: 0.14% Portfolio value: 3.38M Avg. open price: $20.4 Current price: $14.97 P/L: -26.63% Bought +77.57% shares Q3 2022	share	0.14%	3.38M	$20.4	$14.97	-26.63%	Bought +77.57% shares Q3 2022
Biotechnology Adaptive Biotechnologies Corporation Portfolio share: 0.12% Portfolio value: 3.00M Avg. open price: $41.37 Current price: $8.96 P/L: -78.34% Bought +25.04% shares Q3 2022	share	0.12%	3.00M	$41.37	$8.96	-78.34%	Bought +25.04% shares Q3 2022
iShares Biotechnology ETF Portfolio share: 0.12% Portfolio value: 2.87M Avg. open price: $90.34 Current price: $138.43 P/L: +53.23% N/A Q3 2022	share	0.12%	2.87M	$90.34	$138.43	+53.23%	N/A Q3 2022
Biotechnology Arcutis Biotherapeutics, Inc. Portfolio share: 0.12% Portfolio value: 2.84M Avg. open price: $19.26 Current price: $17.51 P/L: -9.09% Bought +13.10% shares Q2 2022	share	0.12%	2.84M	$19.26	$17.51	-9.09%	Bought +13.10% shares Q2 2022
Biotechnology BeiGene, Ltd. Portfolio share: 0.12% Portfolio value: 2.82M Avg. open price: $195.67 Current price: $201.86 P/L: +3.16% Sold -58.93% shares Q3 2022	share	0.12%	2.82M	$195.67	$201.86	+3.16%	Sold -58.93% shares Q3 2022
Biotechnology Ultragenyx Pharmaceutical Inc. Portfolio share: 0.11% Portfolio value: 2.77M Avg. open price: $74.92 Current price: $40.17 P/L: -46.38% Bought +51.17% shares Q3 2022	share	0.11%	2.77M	$74.92	$40.17	-46.38%	Bought +51.17% shares Q3 2022
Medical Devices STERIS plc Portfolio share: 0.11% Portfolio value: 2.77M Avg. open price: $141.16 Current price: $191.91 P/L: +35.95% Sold -39.73% shares Q3 2021	share	0.11%	2.77M	$141.16	$191.91	+35.95%	Sold -39.73% shares Q3 2021
REIT—Healthcare Facilities Ventas, Inc. Portfolio share: 0.11% Portfolio value: 2.67M Avg. open price: $58.89 Current price: $46.24 P/L: -21.48% Sold -73.13% shares Q3 2022	share	0.11%	2.67M	$58.89	$46.24	-21.48%	Sold -73.13% shares Q3 2022
REIT—Healthcare Facilities Welltower Inc. Portfolio share: 0.11% Portfolio value: 2.66M Avg. open price: $64.08 Current price: $71.08 P/L: +10.92% Sold -79.57% shares Q3 2022	share	0.11%	2.66M	$64.08	$71.08	+10.92%	Sold -79.57% shares Q3 2022
REIT—Healthcare Facilities Physicians Realty Trust Portfolio share: 0.10% Portfolio value: 2.53M Avg. open price: $14.68 Current price: $15.25 P/L: +3.91% Sold -65.96% shares Q3 2022	share	0.10%	2.53M	$14.68	$15.25	+3.91%	Sold -65.96% shares Q3 2022
Medical Devices Koninklijke Philips N.V. Portfolio share: 0.10% Portfolio value: 2.53M Avg. open price: $47.36 Current price: $15.27 P/L: -67.76% Bought +189.48% shares Q3 2021	share	0.10%	2.53M	$47.36	$15.27	-67.76%	Bought +189.48% shares Q3 2021
Medical Devices Cardiovascular Systems, Inc. Portfolio share: 0.10% Portfolio value: 2.42M Avg. open price: N/A Current price: $13.93 P/L: N/A N/A Q3 2022	share	0.10%	2.42M	N/A	$13.93	N/A	N/A Q3 2022
Biotechnology MoonLake Immunotherapeutics Portfolio share: 0.10% Portfolio value: 2.38M Avg. open price: N/A Current price: $10.05 P/L: N/A N/A Q3 2022	share	0.10%	2.38M	N/A	$10.05	N/A	N/A Q3 2022
Biotechnology Xenon Pharmaceuticals Inc. Portfolio share: 0.09% Portfolio value: 2.22M Avg. open price: $29.3 Current price: $38.89 P/L: +32.71% Bought +107.79% shares Q3 2022	share	0.09%	2.22M	$29.3	$38.89	+32.71%	Bought +107.79% shares Q3 2022
Biotechnology Bicycle Therapeutics plc Portfolio share: 0.08% Portfolio value: 2.06M Avg. open price: $20.22 Current price: $31.73 P/L: +56.92% Bought +341.94% shares Q3 2022	share	0.08%	2.06M	$20.22	$31.73	+56.92%	Bought +341.94% shares Q3 2022
Medical Care Facilities Option Care Health, Inc. Portfolio share: 0.08% Portfolio value: 2.04M Avg. open price: N/A Current price: $30.76 P/L: N/A N/A Q3 2022	share	0.08%	2.04M	N/A	$30.76	N/A	N/A Q3 2022
Biotechnology IDEAYA Biosciences, Inc. Portfolio share: 0.08% Portfolio value: 1.98M Avg. open price: N/A Current price: $17.98 P/L: N/A N/A Q3 2022	share	0.08%	1.98M	N/A	$17.98	N/A	N/A Q3 2022
Biotechnology Edgewise Therapeutics, Inc. Portfolio share: 0.08% Portfolio value: 1.91M Avg. open price: $7.96 Current price: $8.86 P/L: +11.31% Bought +222.09% shares Q3 2022	share	0.08%	1.91M	$7.96	$8.86	+11.31%	Bought +222.09% shares Q3 2022
Diagnostics & Research ICON Public Limited Company Portfolio share: 0.08% Portfolio value: 1.91M Avg. open price: $204.96 Current price: $213.07 P/L: +3.96% Sold -87.18% shares Q3 2022	share	0.08%	1.91M	$204.96	$213.07	+3.96%	Sold -87.18% shares Q3 2022
Biotechnology Prometheus Biosciences, Inc. Portfolio share: 0.08% Portfolio value: 1.85M Avg. open price: $37.76 Current price: $40 P/L: +5.93% Sold -35.96% shares Q3 2022	share	0.08%	1.85M	$37.76	$40	+5.93%	Sold -35.96% shares Q3 2022
Drug Manufacturers—Specialty & Generic Perrigo Company plc Portfolio share: 0.07% Portfolio value: 1.82M Avg. open price: $46.37 Current price: $31.94 P/L: -31.12% Bought +373.51% shares Q2 2020	share	0.07%	1.82M	$46.37	$31.94	-31.12%	Bought +373.51% shares Q2 2020
Biotechnology Galera Therapeutics, Inc. Portfolio share: 0.06% Portfolio value: 1.56M Avg. open price: $9.5 Current price: $1.68 P/L: -82.32% Sold -13.77% shares Q3 2021	share	0.06%	1.56M	$9.5	$1.68	-82.32%	Sold -13.77% shares Q3 2021
REIT—Healthcare Facilities Global Medical REIT Inc. Portfolio share: 0.06% Portfolio value: 1.49M Avg. open price: $11.04 Current price: $10.2 P/L: -7.65% Bought +48.10% shares Q1 2020	share	0.06%	1.49M	$11.04	$10.2	-7.65%	Bought +48.10% shares Q1 2020
Diagnostics & Research Medpace Holdings, Inc. Portfolio share: 0.06% Portfolio value: 1.48M Avg. open price: N/A Current price: $209 P/L: N/A Sold -50.00% shares Q1 2022	share	0.06%	1.48M	N/A	$209	N/A	Sold -50.00% shares Q1 2022
Biotechnology Zai Lab Limited Portfolio share: 0.06% Portfolio value: 1.48M Avg. open price: $105.39 Current price: $36.59 P/L: -65.28% Bought +15.40% shares Q4 2021	share	0.06%	1.48M	$105.39	$36.59	-65.28%	Bought +15.40% shares Q4 2021
Biotechnology Pyxis Oncology, Inc. Portfolio share: 0.06% Portfolio value: 1.39M Avg. open price: $10.89 Current price: $1.39 P/L: -87.28% Bought +424.67% shares Q1 2022	share	0.06%	1.39M	$10.89	$1.39	-87.28%	Bought +424.67% shares Q1 2022
Drug Manufacturers—Specialty & Generic Takeda Pharmaceutical Company Limited Portfolio share: 0.06% Portfolio value: 1.36M Avg. open price: $16.47 Current price: $14.82 P/L: -10.04% Sold -50.00% shares Q2 2022	share	0.06%	1.36M	$16.47	$14.82	-10.04%	Sold -50.00% shares Q2 2022
Biotechnology Mereo BioPharma Group plc Portfolio share: 0.05% Portfolio value: 1.33M Avg. open price: $3.19 Current price: $0.84 P/L: -73.73% Bought +48.46% shares Q3 2021	share	0.05%	1.33M	$3.19	$0.84	-73.73%	Bought +48.46% shares Q3 2021
Biotechnology Morphic Holding, Inc. Portfolio share: 0.05% Portfolio value: 1.26M Avg. open price: $40.15 Current price: $28.62 P/L: -28.72% Bought +27.41% shares Q2 2022	share	0.05%	1.26M	$40.15	$28.62	-28.72%	Bought +27.41% shares Q2 2022
Drug Manufacturers—General GSK plc Portfolio share: 0.05% Portfolio value: 1.23M Avg. open price: $31.28 Current price: $35.35 P/L: +13.00% N/A Q3 2022	share	0.05%	1.23M	$31.28	$35.35	+13.00%	N/A Q3 2022
Medical Instruments & Supplies Stevanato Group S.p.A. Portfolio share: 0.05% Portfolio value: 1.20M Avg. open price: N/A Current price: $16 P/L: N/A N/A Q1 2022	share	0.05%	1.20M	N/A	$16	N/A	N/A Q1 2022
Biotechnology Affimed N.V. Portfolio share: 0.05% Portfolio value: 1.20M Avg. open price: $3.51 Current price: $2.09 P/L: -40.40% Sold -35.51% shares Q3 2021	share	0.05%	1.20M	$3.51	$2.09	-40.40%	Sold -35.51% shares Q3 2021
Biotechnology ACADIA Pharmaceuticals Inc. Portfolio share: 0.05% Portfolio value: 1.18M Avg. open price: $36.31 Current price: $15.76 P/L: -56.60% N/A Q4 2021	share	0.05%	1.18M	$36.31	$15.76	-56.60%	N/A Q4 2021
Biotechnology Novavax, Inc. Portfolio share: 0.05% Portfolio value: 1.16M Avg. open price: $150.73 Current price: $16.52 P/L: -89.04% Sold -57.89% shares Q4 2021	share	0.05%	1.16M	$150.73	$16.52	-89.04%	Sold -57.89% shares Q4 2021
Biotechnology Avidity Biosciences, Inc. Portfolio share: 0.04% Portfolio value: 1.05M Avg. open price: $18.47 Current price: $11.63 P/L: -37.03% Sold -24.17% shares Q3 2022	share	0.04%	1.05M	$18.47	$11.63	-37.03%	Sold -24.17% shares Q3 2022
Biotechnology Protagonist Therapeutics, Inc. Portfolio share: 0.04% Portfolio value: 1.03M Avg. open price: $20.82 Current price: $8.07 P/L: -61.24% N/A Q3 2022	share	0.04%	1.03M	$20.82	$8.07	-61.24%	N/A Q3 2022
Diagnostics & Research Natera, Inc. Portfolio share: 0.04% Portfolio value: 938K Avg. open price: N/A Current price: $41.84 P/L: N/A N/A Q2 2022	share	0.04%	938K	N/A	$41.84	N/A	N/A Q2 2022
Drug Manufacturers—Specialty & Generic Assertio Holdings, Inc. Portfolio share: 0.04% Portfolio value: 932K Avg. open price: N/A Current price: $3.06 P/L: N/A N/A Q2 2021	share	0.04%	932K	N/A	$3.06	N/A	N/A Q2 2021
Biotechnology Sutro Biopharma, Inc. Portfolio share: 0.04% Portfolio value: 910K Avg. open price: $9.15 Current price: $7.1 P/L: -22.43% Sold -50.00% shares Q1 2022	share	0.04%	910K	$9.15	$7.1	-22.43%	Sold -50.00% shares Q1 2022
Biotechnology Scholar Rock Holding Corporation Portfolio share: 0.03% Portfolio value: 754K Avg. open price: $50.66 Current price: $7.87 P/L: -84.47% Bought +127.36% shares Q2 2021	share	0.03%	754K	$50.66	$7.87	-84.47%	Bought +127.36% shares Q2 2021
Biotechnology Beam Therapeutics Inc. Portfolio share: 0.03% Portfolio value: 754K Avg. open price: N/A Current price: $46.82 P/L: N/A N/A Q4 2021	share	0.03%	754K	N/A	$46.82	N/A	N/A Q4 2021
Biotechnology Intercept Pharmaceuticals, Inc. Portfolio share: 0.03% Portfolio value: 726K Avg. open price: $82.57 Current price: $14.62 P/L: -82.29% Sold -32.44% shares Q3 2021	share	0.03%	726K	$82.57	$14.62	-82.29%	Sold -32.44% shares Q3 2021
Biotechnology I-Mab Portfolio share: 0.03% Portfolio value: 652K Avg. open price: N/A Current price: $3.82 P/L: N/A Sold -2.59% shares Q2 2021	share	0.03%	652K	N/A	$3.82	N/A	Sold -2.59% shares Q2 2021
Biotechnology Ardelyx, Inc. Portfolio share: 0.03% Portfolio value: 642K Avg. open price: $17.69 Current price: $1.85 P/L: -89.54% Sold -11.24% shares Q2 2021	share	0.03%	642K	$17.69	$1.85	-89.54%	Sold -11.24% shares Q2 2021
Biotechnology ALX Oncology Holdings Inc. Portfolio share: 0.03% Portfolio value: 634K Avg. open price: $73.86 Current price: $11.35 P/L: -84.63% Bought +832.68% shares Q4 2021	share	0.03%	634K	$73.86	$11.35	-84.63%	Bought +832.68% shares Q4 2021
Biotechnology TScan Therapeutics, Inc. Portfolio share: 0.03% Portfolio value: 610K Avg. open price: N/A Current price: $2.26 P/L: N/A N/A Q3 2021	share	0.03%	610K	N/A	$2.26	N/A	N/A Q3 2021
Biotechnology Fusion Pharmaceuticals Inc. Portfolio share: 0.02% Portfolio value: 605K Avg. open price: $2.49 Current price: $2.27 P/L: -8.84% Bought +134.90% shares Q3 2022	share	0.02%	605K	$2.49	$2.27	-8.84%	Bought +134.90% shares Q3 2022
Biotechnology Theseus Pharmaceuticals, Inc. Portfolio share: 0.02% Portfolio value: 580K Avg. open price: N/A Current price: $6.52 P/L: N/A N/A Q4 2021	share	0.02%	580K	N/A	$6.52	N/A	N/A Q4 2021
Biotechnology Adicet Bio, Inc. Portfolio share: 0.02% Portfolio value: 573K Avg. open price: N/A Current price: $19.26 P/L: N/A Sold -36.32% shares Q3 2022	share	0.02%	573K	N/A	$19.26	N/A	Sold -36.32% shares Q3 2022
REIT—Healthcare Facilities National Health Investors, Inc. Portfolio share: 0.02% Portfolio value: 567K Avg. open price: N/A Current price: $56.96 P/L: N/A N/A Q1 2020	share	0.02%	567K	N/A	$56.96	N/A	N/A Q1 2020
Health Information Services 1Life Healthcare, Inc. Portfolio share: 0.02% Portfolio value: 536K Avg. open price: N/A Current price: $16.9 P/L: N/A N/A Q1 2021	share	0.02%	536K	N/A	$16.9	N/A	N/A Q1 2021
REIT—Healthcare Facilities Community Healthcare Trust Incorporated Portfolio share: 0.02% Portfolio value: 488K Avg. open price: N/A Current price: $36.13 P/L: N/A N/A Q4 2019	share	0.02%	488K	N/A	$36.13	N/A	N/A Q4 2019
Terumo Corp. Portfolio share: 0.02% Portfolio value: 487K Avg. open price: N/A Current price: N/A P/L: N/A N/A Q3 2022	share	0.02%	487K	N/A	N/A	N/A	N/A Q3 2022
REIT—Healthcare Facilities Universal Health Realty Income Trust Portfolio share: 0.02% Portfolio value: 486K Avg. open price: $109.33 Current price: $53.77 P/L: -50.82% Bought +96.06% shares Q1 2020	share	0.02%	486K	$109.33	$53.77	-50.82%	Bought +96.06% shares Q1 2020
Biotechnology Codexis, Inc. Portfolio share: 0.02% Portfolio value: 419K Avg. open price: N/A Current price: $5.67 P/L: N/A N/A Q3 2022	share	0.02%	419K	N/A	$5.67	N/A	N/A Q3 2022
Biotechnology MorphoSys AG Portfolio share: 0.02% Portfolio value: 412K Avg. open price: $31.67 Current price: $4.21 P/L: -86.71% Bought +322.21% shares Q3 2020	share	0.02%	412K	$31.67	$4.21	-86.71%	Bought +322.21% shares Q3 2020
Biotechnology Nkarta, Inc. Portfolio share: 0.02% Portfolio value: 381K Avg. open price: N/A Current price: $8.59 P/L: N/A N/A Q1 2021	share	0.02%	381K	N/A	$8.59	N/A	N/A Q1 2021
REIT—Healthcare Facilities Diversified Healthcare Trust Portfolio share: 0.01% Portfolio value: 354K Avg. open price: N/A Current price: $0.99 P/L: N/A N/A Q4 2019	share	0.01%	354K	N/A	$0.99	N/A	N/A Q4 2019
Biotechnology Repare Therapeutics Inc. Portfolio share: 0.01% Portfolio value: 354K Avg. open price: N/A Current price: $17.32 P/L: N/A N/A Q4 2021	share	0.01%	354K	N/A	$17.32	N/A	N/A Q4 2021
Biotechnology Precision BioSciences, Inc. Portfolio share: 0.01% Portfolio value: 292K Avg. open price: $11.54 Current price: $1.34 P/L: -88.39% Bought +256.40% shares Q4 2021	share	0.01%	292K	$11.54	$1.34	-88.39%	Bought +256.40% shares Q4 2021
Biotechnology Harpoon Therapeutics, Inc. Portfolio share: 0.01% Portfolio value: 252K Avg. open price: N/A Current price: $0.74 P/L: N/A N/A Q1 2022	share	0.01%	252K	N/A	$0.74	N/A	N/A Q1 2022
Biotechnology Black Diamond Therapeutics, Inc. Portfolio share: 0.01% Portfolio value: 223K Avg. open price: N/A Current price: $1.97 P/L: N/A N/A Q1 2021	share	0.01%	223K	N/A	$1.97	N/A	N/A Q1 2021
Medical Care Facilities Community Health Systems, Inc. Portfolio share: 0.01% Portfolio value: 190K Avg. open price: N/A Current price: $3.45 P/L: N/A Sold -13.00% shares Q4 2021	share	0.01%	190K	N/A	$3.45	N/A	Sold -13.00% shares Q4 2021
Biotechnology Praxis Precision Medicines, Inc. Portfolio share: 0.01% Portfolio value: 170K Avg. open price: N/A Current price: $2.19 P/L: N/A N/A Q4 2020	share	0.01%	170K	N/A	$2.19	N/A	N/A Q4 2020
Biotechnology ARCA biopharma, Inc. Portfolio share: 0.00% Portfolio value: 67K Avg. open price: N/A Current price: $2.11 P/L: N/A Sold -10.00% shares Q2 2020	share	0.00%	67K	N/A	$2.11	N/A	Sold -10.00% shares Q2 2020
Endo International plc Portfolio share: 0.00% Portfolio value: 48K Avg. open price: N/A Current price: N/A P/L: N/A Sold -6.95% shares Q3 2021	share	0.00%	48K	N/A	N/A	N/A	Sold -6.95% shares Q3 2021
Biotechnology Spectrum Pharmaceuticals, Inc. Portfolio share: 0.00% Portfolio value: 49K Avg. open price: N/A Current price: $0.47 P/L: N/A N/A Q3 2018	share	0.00%	49K	N/A	$0.47	N/A	N/A Q3 2018
Biotechnology VYNE Therapeutics Inc. Portfolio share: 0.00% Portfolio value: 30K Avg. open price: N/A Current price: $0.23 P/L: N/A N/A Q1 2021	share	0.00%	30K	N/A	$0.23	N/A	N/A Q1 2021
Biotechnology Corbus Pharmaceuticals Holdings, Inc. Portfolio share: 0.00% Portfolio value: 25K Avg. open price: $8.39 Current price: $0.13 P/L: -98.44% Sold -62.68% shares Q4 2021	share	0.00%	25K	$8.39	$0.13	-98.44%	Sold -62.68% shares Q4 2021
Medical Care Facilities AlerisLife Inc. Portfolio share: 0.00% Portfolio value: 23K Avg. open price: N/A Current price: $0.78 P/L: N/A N/A Q1 2020	share	0.00%	23K	N/A	$0.78	N/A	N/A Q1 2020
Biotechnology Bellicum Pharmaceuticals, Inc. Portfolio share: 0.00% Portfolio value: 7K Avg. open price: N/A Current price: $1.02 P/L: N/A N/A Q1 2020	share	0.00%	7K	N/A	$1.02	N/A	N/A Q1 2020
Medical Instruments & Supplies NEXGEL, Inc. Portfolio share: 0.00% Portfolio value: 6K Avg. open price: N/A Current price: $1.2 P/L: N/A N/A Q1 2022	share	0.00%	6K	N/A	$1.2	N/A	N/A Q1 2022
Biotechnology Cogent Biosciences, Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: N/A Current price: $12.91 P/L: N/A Sold -100.00% shares Q3 2022	share	0.00%	0	N/A	$12.91	N/A	Sold -100.00% shares Q3 2022
Medical Devices ZimVie Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: N/A Current price: $9.21 P/L: N/A Sold -100.00% shares Q3 2022	share	0.00%	0	N/A	$9.21	N/A	Sold -100.00% shares Q3 2022
REIT—Healthcare Facilities Healthcare Trust of America, Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: $27.83 Current price: $29.19 P/L: +4.89% Sold -100.00% shares Q3 2022	share	0.00%	0	$27.83	$29.19	+4.89%	Sold -100.00% shares Q3 2022
Biotechnology Blueprint Medicines Corporation Portfolio share: 0.00% Portfolio value: 0 Avg. open price: $82.73 Current price: $48.93 P/L: -40.85% Sold -100.00% shares Q3 2022	share	0.00%	0	$82.73	$48.93	-40.85%	Sold -100.00% shares Q3 2022
Biotechnology Verona Pharma plc Portfolio share: 0.00% Portfolio value: 0 Avg. open price: $5.54 Current price: $13.94 P/L: +151.40% Sold -100.00% shares Q3 2022	share	0.00%	0	$5.54	$13.94	+151.40%	Sold -100.00% shares Q3 2022
Drug Manufacturers—Specialty & Generic Embecta Corp. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: N/A Current price: $33.76 P/L: N/A Sold -100.00% shares Q3 2022	share	0.00%	0	N/A	$33.76	N/A	Sold -100.00% shares Q3 2022
Medical Instruments & Supplies Becton, Dickinson and Company Portfolio share: 0.00% Portfolio value: 0 Avg. open price: $235.4 Current price: $252.38 P/L: +7.21% Sold -100.00% shares Q3 2022	share	0.00%	0	$235.4	$252.38	+7.21%	Sold -100.00% shares Q3 2022
Diagnostics & Research Syneos Health, Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: $69.22 Current price: $34.92 P/L: -49.56% Sold -100.00% shares Q3 2022	share	0.00%	0	$69.22	$34.92	-49.56%	Sold -100.00% shares Q3 2022
Biotechnology Syndax Pharmaceuticals, Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: N/A Current price: $25.07 P/L: N/A Sold -100.00% shares Q3 2022	share	0.00%	0	N/A	$25.07	N/A	Sold -100.00% shares Q3 2022
Biotechnology Aurinia Pharmaceuticals Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: $15.48 Current price: $5.1 P/L: -67.06% Sold -100.00% shares Q3 2022	share	0.00%	0	$15.48	$5.1	-67.06%	Sold -100.00% shares Q3 2022
Medical Instruments & Supplies Hologic, Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: $48.4 Current price: $76.5 P/L: +58.06% Sold -100.00% shares Q3 2022	share	0.00%	0	$48.4	$76.5	+58.06%	Sold -100.00% shares Q3 2022
Medical Care Facilities Universal Health Services, Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: $117.55 Current price: $129.35 P/L: +10.03% Sold -100.00% shares Q3 2022	share	0.00%	0	$117.55	$129.35	+10.03%	Sold -100.00% shares Q3 2022
Biotechnology iTeos Therapeutics, Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: N/A Current price: $20.03 P/L: N/A Sold -100.00% shares Q3 2022	share	0.00%	0	N/A	$20.03	N/A	Sold -100.00% shares Q3 2022
Biotechnology Fulcrum Therapeutics, Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: $28.21 Current price: $6.75 P/L: -76.07% Sold -100.00% shares Q3 2022	share	0.00%	0	$28.21	$6.75	-76.07%	Sold -100.00% shares Q3 2022
Biotechnology Fate Therapeutics, Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: $22.8 Current price: $20.91 P/L: -8.31% Sold -100.00% shares Q3 2022	share	0.00%	0	$22.8	$20.91	-8.31%	Sold -100.00% shares Q3 2022
Diagnostics & Research Qiagen N.V. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: N/A Current price: $50.35 P/L: N/A Sold -100.00% shares Q3 2022	share	0.00%	0	N/A	$50.35	N/A	Sold -100.00% shares Q3 2022
Medical Care Facilities AMN Healthcare Services, Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: N/A Current price: $123.88 P/L: N/A Sold -100.00% shares Q3 2022	share	0.00%	0	N/A	$123.88	N/A	Sold -100.00% shares Q3 2022
REIT—Healthcare Facilities Healthcare Realty Trust Incorporated Portfolio share: 0.00% Portfolio value: 0 Avg. open price: $30.79 Current price: $20.43 P/L: -33.66% Sold -100.00% shares Q3 2022	share	0.00%	0	$30.79	$20.43	-33.66%	Sold -100.00% shares Q3 2022
Biotechnology Protagonist Therapeutics, Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: $20.82 Current price: $8.07 P/L: -61.24% Sold -100.00% shares Q3 2022	share	0.00%	0	$20.82	$8.07	-61.24%	Sold -100.00% shares Q3 2022
Diagnostics & Research Waters Corporation Portfolio share: 0.00% Portfolio value: 0 Avg. open price: $180.62 Current price: $347.37 P/L: +92.32% Sold -100.00% shares Q3 2022	share	0.00%	0	$180.62	$347.37	+92.32%	Sold -100.00% shares Q3 2022

Showing TOP 188 TEKLA CAPITAL MANAGEMENT's 13F holdings.

Frequently Asked Questions (FAQ)

What is the biggest position of TEKLA CAPITAL MANAGEMENT LLC?

The biggest position of the TEKLA CAPITAL MANAGEMENT LLC is UnitedHealth Group Incorporated (UNH) with 5.67% portfolio share worth of 138.4M US dollars.

Top 5 TEKLA CAPITAL MANAGEMENT's holdings represent 23.51% of the portfolio:

UnitedHealth Group Incorporated (UNH) – 5.67%
Johnson & Johnson (JNJ) – 5.24%
Amgen Inc. (AMGN) – 4.79%
Gilead Sciences, Inc. (GILD) – 4.1%
Vertex Pharmaceuticals Incorporated (VRTX) – 3.71%

Who is the portfolio manager of TEKLA CAPITAL MANAGEMENT LLC?

The portfolio manager of the TEKLA CAPITAL MANAGEMENT LLC is .

What is the total asset value of the TEKLA CAPITAL MANAGEMENT LLC portfolio?

TEKLA CAPITAL MANAGEMENT LLC total asset value (portfolio value) is 2.44B US dollars.

Who is ?

is the portfolio manager of the TEKLA CAPITAL MANAGEMENT LLC.

What is (TEKLA CAPITAL MANAGEMENT LLC) fund performance?

TEKLA CAPITAL MANAGEMENT's quarterly performance is -2.06%, annualy -16.23%. In the past 3 years, the value of 's portfolio has increased by +22%. In the past 5 years, the value of the portfolio has increased by +18%.

What is the TEKLA CAPITAL MANAGEMENT LLC CIK?

TEKLA CAPITAL MANAGEMENT's Central Index Key is 0001300336 .

TEKLA CAPITAL MANAGEMENT LLC Holdings

TEKLA CAPITAL MANAGEMENT LLC portfolio value:

TEKLA CAPITAL MANAGEMENT LLC quarter portfolio value change:

TEKLA CAPITAL MANAGEMENT LLC 1 year portfolio value change:

TEKLA CAPITAL MANAGEMENT LLC 3 years portfolio value change:

TEKLA CAPITAL MANAGEMENT LLC 5 years portfolio value change: