SPHERA FUNDS MANAGEMENT LTD. Holdings

SPHERA FUNDS MANAGEMENT LTD. is an investment fund managing more than 720.46M US dollars. The largest holdings include Invesco QQQ Trust, AstraZeneca and Eli Lilly and Company. In Q3 2022 the fund bought assets of total value of 177.06M US dollars and sold assets of total value of 137.76M US dollars.

$720.45M

portfolio value

-1.95%

quarter

-13.99%

1 year

+24.51%

3 years

+28.13%

5 years

SPHERA FUNDS MANAGEMENT LTD. portfolio changes

Portfolio changes (number of shares)
Period	Buy	Sel
Q1 2016	39358000	205526000
Q2 2016	118856000	136581000
Q3 2016	158365000	77181000
Q4 2016	62129000	140263000
Q1 2017	160758000	75198000
Q2 2017	163202000	72812000
Q3 2017	147125000	99635000
Q4 2017	148725000	103217000
Q1 2018	161403000	200953000
Q2 2018	214015000	176552000
Q3 2018	284700000	151904000
Q4 2018	143296000	194475000
Q1 2019	200526000	145541000
Q2 2019	170107000	215568000
Q3 2019	213113000	205667000
Q4 2019	222821000	111584000
Q1 2020	159091000	285906000
Q2 2020	369590000	135894000
Q3 2020	244314000	209231000
Q4 2020	405856000	293538000
Q1 2021	421588000	326719000
Q2 2021	319978000	267672000
Q3 2021	277711000	355629000
Q4 2021	186291000	368287000
Q1 2022	122160000	331717000
Q2 2022	116264000	185371000
Q3 2022	177063000	137762000

SPHERA FUNDS MANAGEMENT LTD. 13F holdings

Stock	Position type	Portfolio share	Portfolio value	Avg. open price	Current price	P/L	Last change
Invesco QQQ Trust Portfolio share: 12.07% Portfolio value: 86.99M Avg. open price: $245.93 Current price: $287.73 P/L: +17.00% N/A Q3 2022	put	12.07%	86.99M	$245.93	$287.73	+17.00%	N/A Q3 2022
Drug Manufacturers—General AstraZeneca PLC Portfolio share: 6.83% Portfolio value: 49.19M Avg. open price: $47.34 Current price: $68.42 P/L: +44.54% Bought +12.33% shares Q3 2022	share	6.83%	49.19M	$47.34	$68.42	+44.54%	Bought +12.33% shares Q3 2022
Drug Manufacturers—General Eli Lilly and Company Portfolio share: 6.44% Portfolio value: 46.41M Avg. open price: $189.96 Current price: $369.29 P/L: +94.40% Bought +8.54% shares Q3 2022	share	6.44%	46.41M	$189.96	$369.29	+94.40%	Bought +8.54% shares Q3 2022
Drug Manufacturers—General Sanofi Portfolio share: 6.41% Portfolio value: 46.17M Avg. open price: $45.92 Current price: $44.93 P/L: -2.16% Bought +43.52% shares Q3 2022	share	6.41%	46.17M	$45.92	$44.93	-2.16%	Bought +43.52% shares Q3 2022
Drug Manufacturers—General Johnson & Johnson Portfolio share: 4.90% Portfolio value: 35.31M Avg. open price: $147.17 Current price: $178.78 P/L: +21.48% Sold -21.81% shares Q3 2022	share	4.90%	35.31M	$147.17	$178.78	+21.48%	Sold -21.81% shares Q3 2022
Drug Manufacturers—General Merck & Co., Inc. Portfolio share: 4.39% Portfolio value: 31.60M Avg. open price: $63.54 Current price: $110.01 P/L: +73.13% Bought +28.77% shares Q3 2022	share	4.39%	31.60M	$63.54	$110.01	+73.13%	Bought +28.77% shares Q3 2022
Biotechnology Novo Nordisk A/S Portfolio share: 4.10% Portfolio value: 29.53M Avg. open price: $64.24 Current price: $127.08 P/L: +97.81% Bought +13.39% shares Q3 2022	share	4.10%	29.53M	$64.24	$127.08	+97.81%	Bought +13.39% shares Q3 2022
Drug Manufacturers—General AbbVie Inc. Portfolio share: 3.02% Portfolio value: 21.78M Avg. open price: $88.1 Current price: $163.96 P/L: +86.10% Sold -25.69% shares Q3 2022	share	3.02%	21.78M	$88.1	$163.96	+86.10%	Sold -25.69% shares Q3 2022
Semiconductors NVIDIA Corporation Portfolio share: 2.91% Portfolio value: 20.95M Avg. open price: $151.59 Current price: $166.1 P/L: +9.57% N/A Q3 2022	call	2.91%	20.95M	$151.59	$166.1	+9.57%	N/A Q3 2022
Biotechnology Syndax Pharmaceuticals, Inc. Portfolio share: 2.74% Portfolio value: 19.76M Avg. open price: $16.06 Current price: $25.44 P/L: +58.45% Sold -27.79% shares Q3 2022	share	2.74%	19.76M	$16.06	$25.44	+58.45%	Sold -27.79% shares Q3 2022
Drug Manufacturers—Specialty & Generic Teva Pharmaceutical Industries Limited Portfolio share: 2.48% Portfolio value: 17.83M Avg. open price: N/A Current price: $8.7 P/L: N/A N/A Q3 2022	call	2.48%	17.83M	N/A	$8.7	N/A	N/A Q3 2022
Drug Manufacturers—General Biogen Inc. Portfolio share: 2.06% Portfolio value: 14.81M Avg. open price: $275.07 Current price: $292.75 P/L: +6.43% N/A Q3 2022	share	2.06%	14.81M	$275.07	$292.75	+6.43%	N/A Q3 2022
Biotechnology Crinetics Pharmaceuticals, Inc. Portfolio share: 1.71% Portfolio value: 12.30M Avg. open price: $18.58 Current price: $18.32 P/L: -1.40% Bought +6.77% shares Q3 2022	share	1.71%	12.30M	$18.58	$18.32	-1.40%	Bought +6.77% shares Q3 2022
Software—Application Unity Software Inc. Portfolio share: 1.63% Portfolio value: 11.70M Avg. open price: N/A Current price: $38.08 P/L: N/A N/A Q3 2022	call	1.63%	11.70M	N/A	$38.08	N/A	N/A Q3 2022
Biotechnology Kura Oncology, Inc. Portfolio share: 1.50% Portfolio value: 10.79M Avg. open price: $25.73 Current price: $15.82 P/L: -38.51% Bought +59.72% shares Q3 2022	share	1.50%	10.79M	$25.73	$15.82	-38.51%	Bought +59.72% shares Q3 2022
Biotechnology Kezar Life Sciences, Inc. Portfolio share: 1.49% Portfolio value: 10.72M Avg. open price: $9.15 Current price: $7.07 P/L: -22.77% Bought +315.75% shares Q3 2022	share	1.49%	10.72M	$9.15	$7.07	-22.77%	Bought +315.75% shares Q3 2022
Biotechnology Chinook Therapeutics, Inc. Portfolio share: 1.46% Portfolio value: 10.50M Avg. open price: $16.2 Current price: $22.77 P/L: +40.54% Sold -16.99% shares Q3 2022	share	1.46%	10.50M	$16.2	$22.77	+40.54%	Sold -16.99% shares Q3 2022
Biotechnology IVERIC bio, Inc. Portfolio share: 1.45% Portfolio value: 10.43M Avg. open price: $14.78 Current price: $21.89 P/L: +48.15% Sold -39.55% shares Q3 2022	share	1.45%	10.43M	$14.78	$21.89	+48.15%	Sold -39.55% shares Q3 2022
Software—Infrastructure Palo Alto Networks, Inc. Portfolio share: 1.43% Portfolio value: 10.31M Avg. open price: $177.97 Current price: $169.99 P/L: -4.49% N/A Q3 2022	share	1.43%	10.31M	$177.97	$169.99	-4.49%	N/A Q3 2022
Software—Infrastructure Wix.com Ltd. Portfolio share: 1.40% Portfolio value: 10.09M Avg. open price: $136.56 Current price: $85.57 P/L: -37.34% N/A Q3 2022	share	1.40%	10.09M	$136.56	$85.57	-37.34%	N/A Q3 2022
Biotechnology SpringWorks Therapeutics, Inc. Portfolio share: 1.19% Portfolio value: 8.60M Avg. open price: $67.17 Current price: $24.25 P/L: -63.89% Sold -43.80% shares Q3 2022	share	1.19%	8.60M	$67.17	$24.25	-63.89%	Sold -43.80% shares Q3 2022
Specialty Industrial Machinery Kornit Digital Ltd. Portfolio share: 1.19% Portfolio value: 8.59M Avg. open price: $27.35 Current price: $24.09 P/L: -11.91% N/A Q3 2022	share	1.19%	8.59M	$27.35	$24.09	-11.91%	N/A Q3 2022
Internet Retail Global-e Online Ltd. Portfolio share: 1.16% Portfolio value: 8.33M Avg. open price: N/A Current price: $22.02 P/L: N/A N/A Q3 2022	share	1.16%	8.33M	N/A	$22.02	N/A	N/A Q3 2022
Biotechnology POINT Biopharma Global Inc. Portfolio share: 1.13% Portfolio value: 8.13M Avg. open price: N/A Current price: $6.72 P/L: N/A N/A Q3 2022	share	1.13%	8.13M	N/A	$6.72	N/A	N/A Q3 2022
Software—Infrastructure Adobe Inc. Portfolio share: 1.11% Portfolio value: 8.02M Avg. open price: N/A Current price: $334.28 P/L: N/A N/A Q3 2022	share	1.11%	8.02M	N/A	$334.28	N/A	N/A Q3 2022
Biotechnology Immatics N.V. Portfolio share: 1.10% Portfolio value: 7.95M Avg. open price: $8.54 Current price: $11.13 P/L: +30.36% Bought +8.85% shares Q3 2022	share	1.10%	7.95M	$8.54	$11.13	+30.36%	Bought +8.85% shares Q3 2022
Internet Content & Information Perion Network Ltd. Portfolio share: 1.08% Portfolio value: 7.81M Avg. open price: $23.95 Current price: $27.7 P/L: +15.66% N/A Q3 2022	share	1.08%	7.81M	$23.95	$27.7	+15.66%	N/A Q3 2022
Biotechnology Keros Therapeutics, Inc. Portfolio share: 1.08% Portfolio value: 7.78M Avg. open price: $31.22 Current price: $50 P/L: +60.13% Bought +204.16% shares Q3 2022	share	1.08%	7.78M	$31.22	$50	+60.13%	Bought +204.16% shares Q3 2022
Biotechnology Altimmune, Inc. Portfolio share: 1.06% Portfolio value: 7.66M Avg. open price: $9.63 Current price: $11.09 P/L: +15.12% Sold -56.90% shares Q3 2022	share	1.06%	7.66M	$9.63	$11.09	+15.12%	Sold -56.90% shares Q3 2022
Biotechnology Ultragenyx Pharmaceutical Inc. Portfolio share: 1.00% Portfolio value: 7.19M Avg. open price: N/A Current price: $39.83 P/L: N/A N/A Q3 2022	share	1.00%	7.19M	N/A	$39.83	N/A	N/A Q3 2022
Software—Infrastructure SentinelOne, Inc. Portfolio share: 0.99% Portfolio value: 7.15M Avg. open price: N/A Current price: $14.25 P/L: N/A N/A Q3 2022	share	0.99%	7.15M	N/A	$14.25	N/A	N/A Q3 2022
Biotechnology Relmada Therapeutics, Inc. Portfolio share: 0.99% Portfolio value: 7.15M Avg. open price: $26.99 Current price: $4.45 P/L: -83.51% Sold -58.61% shares Q3 2022	share	0.99%	7.15M	$26.99	$4.45	-83.51%	Sold -58.61% shares Q3 2022
Biotechnology Albireo Pharma, Inc. Portfolio share: 0.96% Portfolio value: 6.95M Avg. open price: $20.6 Current price: $22.7 P/L: +10.19% N/A Q3 2022	share	0.96%	6.95M	$20.6	$22.7	+10.19%	N/A Q3 2022
Solar SolarEdge Technologies, Inc. Portfolio share: 0.95% Portfolio value: 6.81M Avg. open price: $44.81 Current price: $314.06 P/L: +600.86% N/A Q3 2022	share	0.95%	6.81M	$44.81	$314.06	+600.86%	N/A Q3 2022
Drug Manufacturers—General Gilead Sciences, Inc. Portfolio share: 0.90% Portfolio value: 6.48M Avg. open price: $63.64 Current price: $87.98 P/L: +38.25% N/A Q3 2022	share	0.90%	6.48M	$63.64	$87.98	+38.25%	N/A Q3 2022
Biotechnology Concert Pharmaceuticals, Inc. Portfolio share: 0.89% Portfolio value: 6.38M Avg. open price: $8.14 Current price: $4.76 P/L: -41.51% Bought +40.24% shares Q3 2022	share	0.89%	6.38M	$8.14	$4.76	-41.51%	Bought +40.24% shares Q3 2022
Specialty Industrial Machinery Generac Holdings Inc. Portfolio share: 0.88% Portfolio value: 6.34M Avg. open price: $194.27 Current price: $96.6 P/L: -50.28% N/A Q3 2022	call	0.88%	6.34M	$194.27	$96.6	-50.28%	N/A Q3 2022
Biotechnology Merus N.V. Portfolio share: 0.87% Portfolio value: 6.27M Avg. open price: $23.35 Current price: $14.2 P/L: -39.18% Sold -23.42% shares Q3 2022	share	0.87%	6.27M	$23.35	$14.2	-39.18%	Sold -23.42% shares Q3 2022
Biotechnology Arcellx, Inc. Portfolio share: 0.87% Portfolio value: 6.27M Avg. open price: N/A Current price: $19.45 P/L: N/A N/A Q3 2022	share	0.87%	6.27M	N/A	$19.45	N/A	N/A Q3 2022
Drug Manufacturers—Specialty & Generic Teva Pharmaceutical Industries Limited Portfolio share: 0.87% Portfolio value: 6.26M Avg. open price: $12.57 Current price: $8.62 P/L: -31.43% Sold -32.37% shares Q3 2022	share	0.87%	6.26M	$12.57	$8.62	-31.43%	Sold -32.37% shares Q3 2022
Biotechnology BELLUS Health Inc. Portfolio share: 0.68% Portfolio value: 4.90M Avg. open price: N/A Current price: $10.02 P/L: N/A N/A Q3 2022	share	0.68%	4.90M	N/A	$10.02	N/A	N/A Q3 2022
Semiconductors NVIDIA Corporation Portfolio share: 0.67% Portfolio value: 4.85M Avg. open price: $151.59 Current price: $166.1 P/L: +9.57% Bought +254.36% shares Q3 2022	share	0.67%	4.85M	$151.59	$166.1	+9.57%	Bought +254.36% shares Q3 2022
Software—Infrastructure SentinelOne, Inc. Portfolio share: 0.58% Portfolio value: 4.21M Avg. open price: N/A Current price: $14.25 P/L: N/A N/A Q3 2022	call	0.58%	4.21M	N/A	$14.25	N/A	N/A Q3 2022
Biotechnology CinCor Pharma, Inc. Portfolio share: 0.54% Portfolio value: 3.90M Avg. open price: N/A Current price: $12.33 P/L: N/A N/A Q3 2022	share	0.54%	3.90M	N/A	$12.33	N/A	N/A Q3 2022
FIVERR INTL LTD Portfolio share: 0.54% Portfolio value: 3.9M Avg. open price: N/A Current price: N/A P/L: N/A Sold -61.92% shares Q1 2022	share	0.54%	3.9M	N/A	N/A	N/A	Sold -61.92% shares Q1 2022
Biotechnology 89bio, Inc. Portfolio share: 0.53% Portfolio value: 3.81M Avg. open price: $4.34 Current price: $8.34 P/L: +92.03% Bought +46.40% shares Q3 2022	share	0.53%	3.81M	$4.34	$8.34	+92.03%	Bought +46.40% shares Q3 2022
Biotechnology Relmada Therapeutics, Inc. Portfolio share: 0.48% Portfolio value: 3.44M Avg. open price: $26.99 Current price: $4.45 P/L: -83.51% N/A Q3 2022	put	0.48%	3.44M	$26.99	$4.45	-83.51%	N/A Q3 2022
Biotechnology Rezolute, Inc. Portfolio share: 0.44% Portfolio value: 3.16M Avg. open price: N/A Current price: $1.71 P/L: N/A N/A Q2 2022	share	0.44%	3.16M	N/A	$1.71	N/A	N/A Q2 2022
Biotechnology Inozyme Pharma, Inc. Portfolio share: 0.44% Portfolio value: 3.14M Avg. open price: $4.77 Current price: $1.36 P/L: -71.49% Bought +0.81% shares Q3 2022	share	0.44%	3.14M	$4.77	$1.36	-71.49%	Bought +0.81% shares Q3 2022
Biotechnology DICE Therapeutics, Inc. Portfolio share: 0.43% Portfolio value: 3.10M Avg. open price: N/A Current price: $34.51 P/L: N/A N/A Q3 2022	share	0.43%	3.10M	N/A	$34.51	N/A	N/A Q3 2022
Biotechnology DICE Therapeutics, Inc. Portfolio share: 0.42% Portfolio value: 3.04M Avg. open price: N/A Current price: $34.51 P/L: N/A N/A Q3 2022	put	0.42%	3.04M	N/A	$34.51	N/A	N/A Q3 2022
Biotechnology Werewolf Therapeutics, Inc. Portfolio share: 0.39% Portfolio value: 2.82M Avg. open price: $4.18 Current price: $1.75 P/L: -58.17% Bought +4.99% shares Q3 2022	share	0.39%	2.82M	$4.18	$1.75	-58.17%	Bought +4.99% shares Q3 2022
Biotechnology Rigel Pharmaceuticals, Inc. Portfolio share: 0.35% Portfolio value: 2.55M Avg. open price: N/A Current price: $0.95 P/L: N/A Sold -14.35% shares Q3 2022	share	0.35%	2.55M	N/A	$0.95	N/A	Sold -14.35% shares Q3 2022
Biotechnology PMV Pharmaceuticals, Inc. Portfolio share: 0.31% Portfolio value: 2.23M Avg. open price: $33.81 Current price: $9.89 P/L: -70.75% N/A Q2 2022	share	0.31%	2.23M	$33.81	$9.89	-70.75%	N/A Q2 2022
Biotechnology Stoke Therapeutics, Inc. Portfolio share: 0.28% Portfolio value: 2.01M Avg. open price: $38.84 Current price: $7.16 P/L: -81.57% N/A Q3 2022	share	0.28%	2.01M	$38.84	$7.16	-81.57%	N/A Q3 2022
Solar Sunrun Inc. Portfolio share: 0.25% Portfolio value: 1.79M Avg. open price: $55.78 Current price: $31.07 P/L: -44.30% N/A Q3 2022	share	0.25%	1.79M	$55.78	$31.07	-44.30%	N/A Q3 2022
Biotechnology Infinity Pharmaceuticals, Inc. Portfolio share: 0.24% Portfolio value: 1.75M Avg. open price: N/A Current price: $0.55 P/L: N/A N/A Q3 2022	share	0.24%	1.75M	N/A	$0.55	N/A	N/A Q3 2022
Biotechnology Alpine Immune Sciences, Inc. Portfolio share: 0.20% Portfolio value: 1.44M Avg. open price: N/A Current price: $6.78 P/L: N/A N/A Q3 2022	share	0.20%	1.44M	N/A	$6.78	N/A	N/A Q3 2022
Biotechnology Altimmune, Inc. Portfolio share: 0.18% Portfolio value: 1.27M Avg. open price: $9.63 Current price: $11.09 P/L: +15.12% N/A Q3 2022	put	0.18%	1.27M	$9.63	$11.09	+15.12%	N/A Q3 2022
Information Technology Services Magic Software Enterprises Ltd. Portfolio share: 0.18% Portfolio value: 1.26M Avg. open price: $10.97 Current price: $17.31 P/L: +57.81% Bought +40.88% shares Q1 2022	share	0.18%	1.26M	$10.97	$17.31	+57.81%	Bought +40.88% shares Q1 2022
Biotechnology Verona Pharma plc Portfolio share: 0.17% Portfolio value: 1.22M Avg. open price: $6.24 Current price: $13.57 P/L: +117.47% N/A Q3 2022	share	0.17%	1.22M	$6.24	$13.57	+117.47%	N/A Q3 2022
Biotechnology Poseida Therapeutics, Inc. Portfolio share: 0.15% Portfolio value: 1.05M Avg. open price: N/A Current price: $5.1 P/L: N/A N/A Q3 2022	share	0.15%	1.05M	N/A	$5.1	N/A	N/A Q3 2022
Biotechnology MediWound Ltd. Portfolio share: 0.13% Portfolio value: 958K Avg. open price: N/A Current price: $1.44 P/L: N/A N/A Q3 2022	share	0.13%	958K	N/A	$1.44	N/A	N/A Q3 2022
Agricultural Inputs ICL Group Ltd Portfolio share: 0.13% Portfolio value: 912K Avg. open price: $3.03 Current price: $8.55 P/L: +182.00% N/A Q3 2022	share	0.13%	912K	$3.03	$8.55	+182.00%	N/A Q3 2022
Software—Application NICE Ltd. Portfolio share: 0.08% Portfolio value: 592K Avg. open price: $134.08 Current price: $196.64 P/L: +46.66% Sold -94.33% shares Q3 2022	share	0.08%	592K	$134.08	$196.64	+46.66%	Sold -94.33% shares Q3 2022
WIX COM LTD Portfolio share: 0.08% Portfolio value: 591K Avg. open price: N/A Current price: N/A P/L: N/A N/A Q2 2022	share	0.08%	591K	N/A	N/A	N/A	N/A Q2 2022
Biotechnology Edgewise Therapeutics, Inc. Portfolio share: 0.08% Portfolio value: 590K Avg. open price: N/A Current price: $8.83 P/L: N/A N/A Q3 2022	share	0.08%	590K	N/A	$8.83	N/A	N/A Q3 2022
NICE SYS INC Portfolio share: 0.08% Portfolio value: 571K Avg. open price: N/A Current price: N/A P/L: N/A N/A Q1 2020	share	0.08%	571K	N/A	N/A	N/A	N/A Q1 2020
Biotechnology Oncorus, Inc. Portfolio share: 0.06% Portfolio value: 459K Avg. open price: N/A Current price: $0.44 P/L: N/A Sold -5.42% shares Q1 2022	share	0.06%	459K	N/A	$0.44	N/A	Sold -5.42% shares Q1 2022
Software—Application Unity Software Inc. Portfolio share: 0.05% Portfolio value: 366K Avg. open price: N/A Current price: $38.08 P/L: N/A N/A Q3 2022	share	0.05%	366K	N/A	$38.08	N/A	N/A Q3 2022
Biotechnology Cyclacel Pharmaceuticals, Inc. Portfolio share: 0.05% Portfolio value: 365K Avg. open price: N/A Current price: $0.77 P/L: N/A N/A Q3 2022	share	0.05%	365K	N/A	$0.77	N/A	N/A Q3 2022
immatics biotechnologies GmbH Portfolio share: 0.04% Portfolio value: 271K Avg. open price: N/A Current price: $3.48 P/L: N/A N/A Q3 2020	share	0.04%	271K	N/A	$3.48	N/A	N/A Q3 2020
Software—Infrastructure Arbe Robotics Ltd. Portfolio share: 0.04% Portfolio value: 259K Avg. open price: N/A Current price: $3.25 P/L: N/A Sold -64.15% shares Q1 2022	share	0.04%	259K	N/A	$3.25	N/A	Sold -64.15% shares Q1 2022
Software—Application Otonomo Technologies Ltd. Portfolio share: 0.02% Portfolio value: 111K Avg. open price: N/A Current price: $0.44 P/L: N/A Sold -33.99% shares Q1 2022	share	0.02%	111K	N/A	$0.44	N/A	Sold -33.99% shares Q1 2022
Drug Manufacturers—Specialty & Generic Teva Pharmaceutical Industries Limited Portfolio share: 0.00% Portfolio value: 0 Avg. open price: $12.57 Current price: $8.62 P/L: -31.43% Sold -100.00% shares Q3 2022	call	0.00%	0	$12.57	$8.62	-31.43%	Sold -100.00% shares Q3 2022
Specialty Industrial Machinery Generac Holdings Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: $194.27 Current price: $96.6 P/L: -50.28% Sold -100.00% shares Q3 2022	share	0.00%	0	$194.27	$96.6	-50.28%	Sold -100.00% shares Q3 2022
Travel Services Airbnb, Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: N/A Current price: $98.51 P/L: N/A Sold -100.00% shares Q3 2022	share	0.00%	0	N/A	$98.51	N/A	Sold -100.00% shares Q3 2022
Biotechnology Vincerx Pharma, Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: $15.11 Current price: $0.7 P/L: -95.37% Sold -100.00% shares Q3 2022	share	0.00%	0	$15.11	$0.7	-95.37%	Sold -100.00% shares Q3 2022
Credit Services Visa Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: $79.11 Current price: $213.68 P/L: +170.10% Sold -100.00% shares Q3 2022	share	0.00%	0	$79.11	$213.68	+170.10%	Sold -100.00% shares Q3 2022
Biotechnology VistaGen Therapeutics, Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: $1.96 Current price: $0.12 P/L: -93.66% Sold -100.00% shares Q3 2022	call	0.00%	0	$1.96	$0.12	-93.66%	Sold -100.00% shares Q3 2022
Biotechnology VistaGen Therapeutics, Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: $1.96 Current price: $0.12 P/L: -93.66% Sold -100.00% shares Q3 2022	share	0.00%	0	$1.96	$0.12	-93.66%	Sold -100.00% shares Q3 2022
Invesco QQQ Trust Portfolio share: 0.00% Portfolio value: 0 Avg. open price: $245.93 Current price: $287.73 P/L: +17.00% Sold -100.00% shares Q3 2022	call	0.00%	0	$245.93	$287.73	+17.00%	Sold -100.00% shares Q3 2022
Invesco QQQ Trust Portfolio share: 0.00% Portfolio value: 0 Avg. open price: $245.93 Current price: $287.73 P/L: +17.00% Sold -100.00% shares Q3 2022	share	0.00%	0	$245.93	$287.73	+17.00%	Sold -100.00% shares Q3 2022
Biotechnology IVERIC bio, Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: $14.78 Current price: $21.89 P/L: +48.15% Sold -100.00% shares Q3 2022	call	0.00%	0	$14.78	$21.89	+48.15%	Sold -100.00% shares Q3 2022
Software—Infrastructure Five9, Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: $121.73 Current price: $66.22 P/L: -45.60% Sold -100.00% shares Q3 2022	share	0.00%	0	$121.73	$66.22	-45.60%	Sold -100.00% shares Q3 2022
Biotechnology C4 Therapeutics, Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: $26.76 Current price: $8.28 P/L: -69.06% Sold -100.00% shares Q3 2022	share	0.00%	0	$26.76	$8.28	-69.06%	Sold -100.00% shares Q3 2022
Internet Content & Information Meta Platforms, Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: N/A Current price: $122.43 P/L: N/A Sold -100.00% shares Q3 2022	share	0.00%	0	N/A	$122.43	N/A	Sold -100.00% shares Q3 2022
Biotechnology Kinnate Biopharma Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: N/A Current price: $7.05 P/L: N/A Sold -100.00% shares Q3 2022	share	0.00%	0	N/A	$7.05	N/A	Sold -100.00% shares Q3 2022
SPDR S&P Biotech ETF Portfolio share: 0.00% Portfolio value: 0 Avg. open price: $87.36 Current price: $82.88 P/L: -5.13% Sold -100.00% shares Q3 2022	share	0.00%	0	$87.36	$82.88	-5.13%	Sold -100.00% shares Q3 2022
SPDR S&P Biotech ETF Portfolio share: 0.00% Portfolio value: 0 Avg. open price: $87.36 Current price: $82.88 P/L: -5.13% Sold -100.00% shares Q3 2022	call	0.00%	0	$87.36	$82.88	-5.13%	Sold -100.00% shares Q3 2022
SPDR S&P 500 ETF Trust Portfolio share: 0.00% Portfolio value: 0 Avg. open price: N/A Current price: $400.01 P/L: N/A Sold -100.00% shares Q3 2022	call	0.00%	0	N/A	$400.01	N/A	Sold -100.00% shares Q3 2022
Biotechnology Amicus Therapeutics, Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: $12.95 Current price: $12.37 P/L: -4.49% Sold -100.00% shares Q3 2022	share	0.00%	0	$12.95	$12.37	-4.49%	Sold -100.00% shares Q3 2022
Semiconductors Advanced Micro Devices, Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: N/A Current price: $73.62 P/L: N/A Sold -100.00% shares Q3 2022	share	0.00%	0	N/A	$73.62	N/A	Sold -100.00% shares Q3 2022
Biotechnology Alnylam Pharmaceuticals, Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: $94.14 Current price: $226.4 P/L: +140.49% Sold -100.00% shares Q3 2022	call	0.00%	0	$94.14	$226.4	+140.49%	Sold -100.00% shares Q3 2022

Showing TOP 94 SPHERA FUNDS MANAGEMENT LTD.'s 13F holdings.

Frequently Asked Questions (FAQ)

What is the biggest position of SPHERA FUNDS MANAGEMENT LTD.?

The biggest position of the SPHERA FUNDS MANAGEMENT LTD. is Invesco QQQ Trust (QQQ) with 12.07% portfolio share worth of 86.99M US dollars.

Top 5 SPHERA FUNDS MANAGEMENT LTD.'s holdings represent 36.66% of the portfolio:

Invesco QQQ Trust (QQQ) – 12.07%
AstraZeneca PLC (AZN) – 6.83%
Eli Lilly and Company (LLY) – 6.44%
Sanofi (SNY) – 6.41%
Johnson & Johnson (JNJ) – 4.9%

Who is the portfolio manager of SPHERA FUNDS MANAGEMENT LTD.?

The portfolio manager of the SPHERA FUNDS MANAGEMENT LTD. is .

What is the total asset value of the SPHERA FUNDS MANAGEMENT LTD. portfolio?

SPHERA FUNDS MANAGEMENT LTD. total asset value (portfolio value) is 720.46M US dollars.

Who is ?

is the portfolio manager of the SPHERA FUNDS MANAGEMENT LTD..

What is (SPHERA FUNDS MANAGEMENT LTD.) fund performance?

SPHERA FUNDS MANAGEMENT LTD.'s quarterly performance is -1.95%, annualy -13.99%. In the past 3 years, the value of 's portfolio has increased by +25%. In the past 5 years, the value of the portfolio has increased by +28%.

What is the SPHERA FUNDS MANAGEMENT LTD. CIK?

SPHERA FUNDS MANAGEMENT LTD.'s Central Index Key is 0001496201 .

SPHERA FUNDS MANAGEMENT LTD. Holdings

SPHERA FUNDS MANAGEMENT LTD. portfolio value:

SPHERA FUNDS MANAGEMENT LTD. quarter portfolio value change:

SPHERA FUNDS MANAGEMENT LTD. 1 year portfolio value change:

SPHERA FUNDS MANAGEMENT LTD. 3 years portfolio value change:

SPHERA FUNDS MANAGEMENT LTD. 5 years portfolio value change: