IKARIAN CAPITAL, LLC Holdings

IKARIAN CAPITAL, LLC is an investment fund managing more than 501.84M US dollars. The largest holdings include Relmada Therapeutics, Relmada Therapeutics and SPDR S&P 500 ETF Trust. In Q3 2022 the fund bought assets of total value of 98.82M US dollars and sold assets of total value of 139.67M US dollars.

$501.83M

portfolio value

+15.48%

quarter

-29.21%

1 year

IKARIAN CAPITAL, LLC portfolio changes

Portfolio changes (number of shares)
Period	Buy	Sel
Q1 2020	188160000	30389000
Q2 2020	145282000	94059000
Q3 2020	154375000	120421000
Q4 2020	240279000	63889000
Q1 2021	302343000	164421000
Q2 2021	145193000	220050000
Q3 2021	131743000	237808000
Q4 2021	88927000	144504000
Q1 2022	41855000	62636000
Q2 2022	77294000	155574000
Q3 2022	98819000	139669000

IKARIAN CAPITAL, LLC 13F holdings

Stock	Position type	Portfolio share	Portfolio value	Avg. open price	Current price	P/L	Last change
Biotechnology Relmada Therapeutics, Inc. Portfolio share: 5.72% Portfolio value: 28.70M Avg. open price: $19.25 Current price: $4.45 P/L: -76.89% Bought +174.64% shares Q3 2022	put	5.72%	28.70M	$19.25	$4.45	-76.89%	Bought +174.64% shares Q3 2022
Biotechnology Relmada Therapeutics, Inc. Portfolio share: 5.72% Portfolio value: 28.70M Avg. open price: $19.25 Current price: $4.45 P/L: -76.89% Bought +158.43% shares Q3 2022	call	5.72%	28.70M	$19.25	$4.45	-76.89%	Bought +158.43% shares Q3 2022
SPDR S&P 500 ETF Trust Portfolio share: 4.27% Portfolio value: 21.43M Avg. open price: $365.65 Current price: $400.01 P/L: +9.40% N/A Q3 2022	put	4.27%	21.43M	$365.65	$400.01	+9.40%	N/A Q3 2022
Biotechnology Seagen Inc. Portfolio share: 4.09% Portfolio value: 20.52M Avg. open price: N/A Current price: $121.22 P/L: N/A N/A Q3 2022	call	4.09%	20.52M	N/A	$121.22	N/A	N/A Q3 2022
Drug Manufacturers—General Biogen Inc. Portfolio share: 3.75% Portfolio value: 18.82M Avg. open price: $281.9 Current price: $292.75 P/L: +3.85% Sold -37.17% shares Q3 2022	call	3.75%	18.82M	$281.9	$292.75	+3.85%	Sold -37.17% shares Q3 2022
Biotechnology Axsome Therapeutics, Inc. Portfolio share: 3.62% Portfolio value: 18.18M Avg. open price: $103.36 Current price: $77.29 P/L: -25.22% Sold -18.48% shares Q3 2022	put	3.62%	18.18M	$103.36	$77.29	-25.22%	Sold -18.48% shares Q3 2022
Biotechnology IVERIC bio, Inc. Portfolio share: 3.50% Portfolio value: 17.55M Avg. open price: $9.64 Current price: $21.89 P/L: +127.18% Bought +1893.49% shares Q3 2022	share	3.50%	17.55M	$9.64	$21.89	+127.18%	Bought +1893.49% shares Q3 2022
Biotechnology DICE Therapeutics, Inc. Portfolio share: 3.03% Portfolio value: 15.18M Avg. open price: N/A Current price: $34.51 P/L: N/A N/A Q3 2022	call	3.03%	15.18M	N/A	$34.51	N/A	N/A Q3 2022
Drug Manufacturers—Specialty & Generic Esperion Therapeutics, Inc. Portfolio share: 2.85% Portfolio value: 14.27M Avg. open price: $6.36 Current price: $7.49 P/L: +17.77% Bought +3.73% shares Q3 2022	share	2.85%	14.27M	$6.36	$7.49	+17.77%	Bought +3.73% shares Q3 2022
Drug Manufacturers—General Biogen Inc. Portfolio share: 2.83% Portfolio value: 14.20M Avg. open price: $281.9 Current price: $292.75 P/L: +3.85% N/A Q3 2022	put	2.83%	14.20M	$281.9	$292.75	+3.85%	N/A Q3 2022
Biotechnology Prometheus Biosciences, Inc. Portfolio share: 2.72% Portfolio value: 13.64M Avg. open price: N/A Current price: $37.72 P/L: N/A N/A Q3 2022	share	2.72%	13.64M	N/A	$37.72	N/A	N/A Q3 2022
SPDR S&P Biotech ETF Portfolio share: 2.37% Portfolio value: 11.89M Avg. open price: $117.53 Current price: $82.88 P/L: -29.48% Sold -57.14% shares Q3 2022	put	2.37%	11.89M	$117.53	$82.88	-29.48%	Sold -57.14% shares Q3 2022
Biotechnology Altimmune, Inc. Portfolio share: 2.14% Portfolio value: 10.76M Avg. open price: $11.63 Current price: $11.09 P/L: -4.65% Bought +177.54% shares Q3 2022	call	2.14%	10.76M	$11.63	$11.09	-4.65%	Bought +177.54% shares Q3 2022
Biotechnology Prometheus Biosciences, Inc. Portfolio share: 2.09% Portfolio value: 10.50M Avg. open price: N/A Current price: $37.72 P/L: N/A N/A Q3 2022	call	2.09%	10.50M	N/A	$37.72	N/A	N/A Q3 2022
Biotechnology DICE Therapeutics, Inc. Portfolio share: 2.04% Portfolio value: 10.22M Avg. open price: N/A Current price: $34.51 P/L: N/A N/A Q3 2022	put	2.04%	10.22M	N/A	$34.51	N/A	N/A Q3 2022
Biotechnology Sarepta Therapeutics, Inc. Portfolio share: 1.88% Portfolio value: 9.41M Avg. open price: $124.14 Current price: $122.96 P/L: -0.95% Sold -14.80% shares Q3 2022	call	1.88%	9.41M	$124.14	$122.96	-0.95%	Sold -14.80% shares Q3 2022
Drug Manufacturers—Specialty & Generic Deciphera Pharmaceuticals, Inc. Portfolio share: 1.81% Portfolio value: 9.10M Avg. open price: N/A Current price: $15.02 P/L: N/A N/A Q3 2022	share	1.81%	9.10M	N/A	$15.02	N/A	N/A Q3 2022
Biotechnology BELLUS Health Inc. Portfolio share: 1.79% Portfolio value: 8.97M Avg. open price: $5.84 Current price: $10.02 P/L: +71.63% Sold -16.52% shares Q3 2022	share	1.79%	8.97M	$5.84	$10.02	+71.63%	Sold -16.52% shares Q3 2022
Biotechnology Celldex Therapeutics, Inc. Portfolio share: 1.78% Portfolio value: 8.92M Avg. open price: $30.96 Current price: $36.66 P/L: +18.42% Sold -40.98% shares Q3 2022	share	1.78%	8.92M	$30.96	$36.66	+18.42%	Sold -40.98% shares Q3 2022
Biotechnology Milestone Pharmaceuticals Inc. Portfolio share: 1.57% Portfolio value: 7.86M Avg. open price: $6.63 Current price: $4.75 P/L: -28.32% Sold -37.97% shares Q3 2022	share	1.57%	7.86M	$6.63	$4.75	-28.32%	Sold -37.97% shares Q3 2022
Biotechnology IVERIC bio, Inc. Portfolio share: 1.57% Portfolio value: 7.85M Avg. open price: $9.64 Current price: $21.89 P/L: +127.18% Bought +79.17% shares Q3 2022	call	1.57%	7.85M	$9.64	$21.89	+127.18%	Bought +79.17% shares Q3 2022
Biotechnology Tricida, Inc. Portfolio share: 1.52% Portfolio value: 7.62M Avg. open price: $9.33 Current price: $0.23 P/L: -97.56% Bought +683.53% shares Q3 2022	put	1.52%	7.62M	$9.33	$0.23	-97.56%	Bought +683.53% shares Q3 2022
Biotechnology Gossamer Bio, Inc. Portfolio share: 1.46% Portfolio value: 7.31M Avg. open price: $10.34 Current price: $9.29 P/L: -10.15% Sold -38.98% shares Q3 2022	share	1.46%	7.31M	$10.34	$9.29	-10.15%	Sold -38.98% shares Q3 2022
Biotechnology Amylyx Pharmaceuticals, Inc. Portfolio share: 1.40% Portfolio value: 7.03M Avg. open price: $12.85 Current price: $38.55 P/L: +200.00% Sold -28.73% shares Q3 2022	call	1.40%	7.03M	$12.85	$38.55	+200.00%	Sold -28.73% shares Q3 2022
Biotechnology Krystal Biotech, Inc. Portfolio share: 1.32% Portfolio value: 6.63M Avg. open price: N/A Current price: $75.78 P/L: N/A N/A Q3 2022	put	1.32%	6.63M	N/A	$75.78	N/A	N/A Q3 2022
Biotechnology Astria Therapeutics, Inc. Portfolio share: 1.26% Portfolio value: 6.32M Avg. open price: $6.05 Current price: $10.32 P/L: +70.67% Bought +18.12% shares Q3 2022	share	1.26%	6.32M	$6.05	$10.32	+70.67%	Bought +18.12% shares Q3 2022
Biotechnology Gossamer Bio, Inc. Portfolio share: 1.26% Portfolio value: 6.30M Avg. open price: $10.34 Current price: $9.29 P/L: -10.15% Bought +57.43% shares Q3 2022	call	1.26%	6.30M	$10.34	$9.29	-10.15%	Bought +57.43% shares Q3 2022
Biotechnology Kezar Life Sciences, Inc. Portfolio share: 1.25% Portfolio value: 6.27M Avg. open price: $16.58 Current price: $7.07 P/L: -57.37% Sold -48.26% shares Q3 2022	share	1.25%	6.27M	$16.58	$7.07	-57.37%	Sold -48.26% shares Q3 2022
Biotechnology Sage Therapeutics, Inc. Portfolio share: 1.23% Portfolio value: 6.18M Avg. open price: $55.04 Current price: $43.52 P/L: -20.92% N/A Q3 2022	share	1.23%	6.18M	$55.04	$43.52	-20.92%	N/A Q3 2022
Biotechnology Tricida, Inc. Portfolio share: 1.21% Portfolio value: 6.05M Avg. open price: $9.33 Current price: $0.23 P/L: -97.56% N/A Q3 2022	call	1.21%	6.05M	$9.33	$0.23	-97.56%	N/A Q3 2022
Biotechnology Altimmune, Inc. Portfolio share: 1.20% Portfolio value: 6.02M Avg. open price: $11.63 Current price: $11.09 P/L: -4.65% Sold -47.40% shares Q3 2022	share	1.20%	6.02M	$11.63	$11.09	-4.65%	Sold -47.40% shares Q3 2022
Biotechnology Xenon Pharmaceuticals Inc. Portfolio share: 1.15% Portfolio value: 5.79M Avg. open price: $17.07 Current price: $38.83 P/L: +127.53% Sold -32.97% shares Q3 2022	share	1.15%	5.79M	$17.07	$38.83	+127.53%	Sold -32.97% shares Q3 2022
Biotechnology Terns Pharmaceuticals, Inc. Portfolio share: 1.06% Portfolio value: 5.32M Avg. open price: $2.48 Current price: $6.09 P/L: +145.56% Bought +29.16% shares Q3 2022	share	1.06%	5.32M	$2.48	$6.09	+145.56%	Bought +29.16% shares Q3 2022
Biotechnology ACADIA Pharmaceuticals Inc. Portfolio share: 1.06% Portfolio value: 5.31M Avg. open price: $30.52 Current price: $15.24 P/L: -50.07% N/A Q3 2022	share	1.06%	5.31M	$30.52	$15.24	-50.07%	N/A Q3 2022
Drug Manufacturers—General Horizon Therapeutics Public Limited Company Portfolio share: 1.05% Portfolio value: 5.26M Avg. open price: $85.61 Current price: $98.48 P/L: +15.03% Sold -14.90% shares Q3 2022	call	1.05%	5.26M	$85.61	$98.48	+15.03%	Sold -14.90% shares Q3 2022
Biotechnology Cerevel Therapeutics Holdings, Inc. Portfolio share: 1.00% Portfolio value: 5.03M Avg. open price: N/A Current price: $28.31 P/L: N/A N/A Q3 2022	share	1.00%	5.03M	N/A	$28.31	N/A	N/A Q3 2022
Biotechnology Stoke Therapeutics, Inc. Portfolio share: 0.94% Portfolio value: 4.73M Avg. open price: N/A Current price: $7.16 P/L: N/A N/A Q3 2022	put	0.94%	4.73M	N/A	$7.16	N/A	N/A Q3 2022
Biotechnology TRACON Pharmaceuticals, Inc. Portfolio share: 0.92% Portfolio value: 4.61M Avg. open price: $4.65 Current price: $1.44 P/L: -69.04% Sold -0.84% shares Q3 2022	share	0.92%	4.61M	$4.65	$1.44	-69.04%	Sold -0.84% shares Q3 2022
Drug Manufacturers—General Horizon Therapeutics Public Limited Company Portfolio share: 0.92% Portfolio value: 4.59M Avg. open price: $85.61 Current price: $98.48 P/L: +15.03% Sold -53.65% shares Q3 2022	share	0.92%	4.59M	$85.61	$98.48	+15.03%	Sold -53.65% shares Q3 2022
Biotechnology Immunovant, Inc. Portfolio share: 0.90% Portfolio value: 4.52M Avg. open price: $16.69 Current price: $14.36 P/L: -13.98% N/A Q3 2022	share	0.90%	4.52M	$16.69	$14.36	-13.98%	N/A Q3 2022
Biotechnology Arvinas, Inc. Portfolio share: 0.89% Portfolio value: 4.45M Avg. open price: $34.52 Current price: $39.53 P/L: +14.50% N/A Q3 2022	call	0.89%	4.45M	$34.52	$39.53	+14.50%	N/A Q3 2022
Biotechnology Prothena Corporation plc Portfolio share: 0.81% Portfolio value: 4.05M Avg. open price: N/A Current price: $60.39 P/L: N/A N/A Q3 2022	call	0.81%	4.05M	N/A	$60.39	N/A	N/A Q3 2022
Biotechnology Ardelyx, Inc. Portfolio share: 0.75% Portfolio value: 3.78M Avg. open price: $3.25 Current price: $1.86 P/L: -42.74% Bought +89.15% shares Q3 2022	share	0.75%	3.78M	$3.25	$1.86	-42.74%	Bought +89.15% shares Q3 2022
Biotechnology Acumen Pharmaceuticals, Inc. Portfolio share: 0.70% Portfolio value: 3.51M Avg. open price: N/A Current price: $5.6 P/L: N/A N/A Q3 2022	share	0.70%	3.51M	N/A	$5.6	N/A	N/A Q3 2022
Biotechnology POINT Biopharma Global Inc. Portfolio share: 0.69% Portfolio value: 3.48M Avg. open price: N/A Current price: $6.72 P/L: N/A N/A Q3 2022	share	0.69%	3.48M	N/A	$6.72	N/A	N/A Q3 2022
Biotechnology Reata Pharmaceuticals, Inc. Portfolio share: 0.69% Portfolio value: 3.47M Avg. open price: $69.69 Current price: $39.62 P/L: -43.15% Sold -14.75% shares Q3 2022	call	0.69%	3.47M	$69.69	$39.62	-43.15%	Sold -14.75% shares Q3 2022
Biotechnology Aerovate Therapeutics, Inc. Portfolio share: 0.66% Portfolio value: 3.31M Avg. open price: N/A Current price: $18 P/L: N/A N/A Q3 2022	share	0.66%	3.31M	N/A	$18	N/A	N/A Q3 2022
ARK Genomic Revolution ETF Portfolio share: 0.63% Portfolio value: 3.17M Avg. open price: $92.87 Current price: $31.5 P/L: -66.08% N/A Q3 2022	share	0.63%	3.17M	$92.87	$31.5	-66.08%	N/A Q3 2022
Biotechnology scPharmaceuticals Inc. Portfolio share: 0.62% Portfolio value: 3.12M Avg. open price: $7.04 Current price: $6.9 P/L: -2.00% Sold -45.77% shares Q3 2022	share	0.62%	3.12M	$7.04	$6.9	-2.00%	Sold -45.77% shares Q3 2022
Biotechnology Milestone Pharmaceuticals Inc. Portfolio share: 0.62% Portfolio value: 3.10M Avg. open price: $6.63 Current price: $4.75 P/L: -28.32% N/A Q3 2022	put	0.62%	3.10M	$6.63	$4.75	-28.32%	N/A Q3 2022
Biotechnology bluebird bio, Inc. Portfolio share: 0.58% Portfolio value: 2.92M Avg. open price: $29.76 Current price: $8.01 P/L: -73.09% N/A Q3 2022	share	0.58%	2.92M	$29.76	$8.01	-73.09%	N/A Q3 2022
Drug Manufacturers—General Biogen Inc. Portfolio share: 0.58% Portfolio value: 2.92M Avg. open price: $281.9 Current price: $292.75 P/L: +3.85% Bought +877.01% shares Q3 2022	share	0.58%	2.92M	$281.9	$292.75	+3.85%	Bought +877.01% shares Q3 2022
Biotechnology Revance Therapeutics, Inc. Portfolio share: 0.54% Portfolio value: 2.7M Avg. open price: N/A Current price: $21.1 P/L: N/A N/A Q3 2022	share	0.54%	2.7M	N/A	$21.1	N/A	N/A Q3 2022
Biotechnology Cogent Biosciences, Inc. Portfolio share: 0.48% Portfolio value: 2.42M Avg. open price: N/A Current price: $12.5 P/L: N/A Sold -34.89% shares Q3 2022	share	0.48%	2.42M	N/A	$12.5	N/A	Sold -34.89% shares Q3 2022
Biotechnology Satsuma Pharmaceuticals, Inc. Portfolio share: 0.48% Portfolio value: 2.4M Avg. open price: $4.85 Current price: $0.89 P/L: -81.61% N/A Q3 2022	call	0.48%	2.4M	$4.85	$0.89	-81.61%	N/A Q3 2022
Drug Manufacturers—Specialty & Generic Deciphera Pharmaceuticals, Inc. Portfolio share: 0.45% Portfolio value: 2.26M Avg. open price: N/A Current price: $15.02 P/L: N/A N/A Q3 2022	call	0.45%	2.26M	N/A	$15.02	N/A	N/A Q3 2022
Biotechnology Insmed Incorporated Portfolio share: 0.43% Portfolio value: 2.15M Avg. open price: $23.88 Current price: $19.89 P/L: -16.71% N/A Q3 2022	call	0.43%	2.15M	$23.88	$19.89	-16.71%	N/A Q3 2022
Biotechnology Sarepta Therapeutics, Inc. Portfolio share: 0.37% Portfolio value: 1.85M Avg. open price: $124.14 Current price: $122.96 P/L: -0.95% Sold -32.76% shares Q3 2022	share	0.37%	1.85M	$124.14	$122.96	-0.95%	Sold -32.76% shares Q3 2022
Biotechnology Lyra Therapeutics, Inc. Portfolio share: 0.34% Portfolio value: 1.72M Avg. open price: $10.76 Current price: $3.39 P/L: -68.49% Sold -1.05% shares Q3 2022	share	0.34%	1.72M	$10.76	$3.39	-68.49%	Sold -1.05% shares Q3 2022
Biotechnology Milestone Pharmaceuticals Inc. Portfolio share: 0.33% Portfolio value: 1.65M Avg. open price: $6.63 Current price: $4.75 P/L: -28.32% Sold -15.11% shares Q3 2022	call	0.33%	1.65M	$6.63	$4.75	-28.32%	Sold -15.11% shares Q3 2022
Biotechnology CinCor Pharma, Inc. Portfolio share: 0.30% Portfolio value: 1.48M Avg. open price: N/A Current price: $12.33 P/L: N/A N/A Q3 2022	share	0.30%	1.48M	N/A	$12.33	N/A	N/A Q3 2022
Biotechnology Akero Therapeutics, Inc. Portfolio share: 0.28% Portfolio value: 1.39M Avg. open price: N/A Current price: $44.04 P/L: N/A N/A Q3 2022	call	0.28%	1.39M	N/A	$44.04	N/A	N/A Q3 2022
Drug Manufacturers—Specialty & Generic Esperion Therapeutics, Inc. Portfolio share: 0.27% Portfolio value: 1.33M Avg. open price: $6.36 Current price: $7.49 P/L: +17.77% N/A Q3 2022	call	0.27%	1.33M	$6.36	$7.49	+17.77%	N/A Q3 2022
Biotechnology Viking Therapeutics, Inc. Portfolio share: 0.25% Portfolio value: 1.26M Avg. open price: $3.16 Current price: $3.97 P/L: +25.80% Sold -44.55% shares Q3 2022	share	0.25%	1.26M	$3.16	$3.97	+25.80%	Sold -44.55% shares Q3 2022
Biotechnology Intercept Pharmaceuticals, Inc. Portfolio share: 0.24% Portfolio value: 1.18M Avg. open price: $43.66 Current price: $14.32 P/L: -67.20% Sold -18.86% shares Q3 2022	share	0.24%	1.18M	$43.66	$14.32	-67.20%	Sold -18.86% shares Q3 2022
Biotechnology Geron Corporation Portfolio share: 0.23% Portfolio value: 1.17M Avg. open price: N/A Current price: $2.29 P/L: N/A N/A Q3 2022	call	0.23%	1.17M	N/A	$2.29	N/A	N/A Q3 2022
Biotechnology 89bio, Inc. Portfolio share: 0.23% Portfolio value: 1.15M Avg. open price: N/A Current price: $8.34 P/L: N/A N/A Q3 2022	share	0.23%	1.15M	N/A	$8.34	N/A	N/A Q3 2022
Biotechnology Ocular Therapeutix, Inc. Portfolio share: 0.22% Portfolio value: 1.09M Avg. open price: $7.02 Current price: $2.99 P/L: -57.44% N/A Q3 2022	share	0.22%	1.09M	$7.02	$2.99	-57.44%	N/A Q3 2022
Biotechnology X4 Pharmaceuticals, Inc. Portfolio share: 0.19% Portfolio value: 973K Avg. open price: $6.73 Current price: $1.29 P/L: -80.83% Sold -66.15% shares Q3 2022	share	0.19%	973K	$6.73	$1.29	-80.83%	Sold -66.15% shares Q3 2022
Biotechnology Clene Inc. Portfolio share: 0.18% Portfolio value: 903K Avg. open price: $10.79 Current price: $1.09 P/L: -89.89% N/A Q3 2022	call	0.18%	903K	$10.79	$1.09	-89.89%	N/A Q3 2022
Biotechnology BELLUS Health Inc. Portfolio share: 0.18% Portfolio value: 900K Avg. open price: $5.84 Current price: $10.02 P/L: +71.63% Sold -14.80% shares Q3 2022	call	0.18%	900K	$5.84	$10.02	+71.63%	Sold -14.80% shares Q3 2022
Biotechnology Seres Therapeutics, Inc. Portfolio share: 0.17% Portfolio value: 843K Avg. open price: $12.56 Current price: $6.53 P/L: -48.02% Sold -75.71% shares Q3 2022	share	0.17%	843K	$12.56	$6.53	-48.02%	Sold -75.71% shares Q3 2022
Biotechnology Brainstorm Cell Therapeutics Inc. Portfolio share: 0.17% Portfolio value: 839K Avg. open price: $4.23 Current price: $1.6 P/L: -62.17% Sold -25.05% shares Q3 2022	share	0.17%	839K	$4.23	$1.6	-62.17%	Sold -25.05% shares Q3 2022
Biotechnology Satsuma Pharmaceuticals, Inc. Portfolio share: 0.16% Portfolio value: 815K Avg. open price: $4.85 Current price: $0.89 P/L: -81.61% Sold -79.18% shares Q3 2022	share	0.16%	815K	$4.85	$0.89	-81.61%	Sold -79.18% shares Q3 2022
Biotechnology Design Therapeutics, Inc. Portfolio share: 0.16% Portfolio value: 811K Avg. open price: N/A Current price: $13.67 P/L: N/A N/A Q3 2022	put	0.16%	811K	N/A	$13.67	N/A	N/A Q3 2022
Biotechnology Renovacor, Inc. Portfolio share: 0.14% Portfolio value: 725K Avg. open price: $8 Current price: $3.2 P/L: -60.00% Sold -1.76% shares Q3 2022	share	0.14%	725K	$8	$3.2	-60.00%	Sold -1.76% shares Q3 2022
Biotechnology Eledon Pharmaceuticals, Inc. Portfolio share: 0.12% Portfolio value: 612K Avg. open price: $9.73 Current price: $2.43 P/L: -75.04% Sold -38.81% shares Q3 2022	share	0.12%	612K	$9.73	$2.43	-75.04%	Sold -38.81% shares Q3 2022
Biotechnology Chemomab Therapeutics Ltd. Portfolio share: 0.12% Portfolio value: 612K Avg. open price: $6.75 Current price: $2.05 P/L: -69.63% Sold -8.28% shares Q3 2022	share	0.12%	612K	$6.75	$2.05	-69.63%	Sold -8.28% shares Q3 2022
Biotechnology Alnylam Pharmaceuticals, Inc. Portfolio share: 0.11% Portfolio value: 560K Avg. open price: $163.29 Current price: $226.4 P/L: +38.65% Sold -95.43% shares Q3 2022	share	0.11%	560K	$163.29	$226.4	+38.65%	Sold -95.43% shares Q3 2022
Biotechnology Protara Therapeutics, Inc. Portfolio share: 0.11% Portfolio value: 558K Avg. open price: $27.47 Current price: $3.63 P/L: -86.79% Sold -26.83% shares Q3 2022	share	0.11%	558K	$27.47	$3.63	-86.79%	Sold -26.83% shares Q3 2022
Biotechnology Autolus Therapeutics plc Portfolio share: 0.11% Portfolio value: 556K Avg. open price: $5.73 Current price: $3.22 P/L: -43.80% Sold -19.28% shares Q3 2022	share	0.11%	556K	$5.73	$3.22	-43.80%	Sold -19.28% shares Q3 2022
Biotechnology Bellicum Pharmaceuticals, Inc. Portfolio share: 0.11% Portfolio value: 537K Avg. open price: $1.43 Current price: $0.99 P/L: -30.77% Sold -14.38% shares Q3 2022	share	0.11%	537K	$1.43	$0.99	-30.77%	Sold -14.38% shares Q3 2022
Biotechnology Reneo Pharmaceuticals, Inc. Portfolio share: 0.10% Portfolio value: 521K Avg. open price: $8.65 Current price: $2.02 P/L: -76.65% Sold -16.04% shares Q3 2022	share	0.10%	521K	$8.65	$2.02	-76.65%	Sold -16.04% shares Q3 2022
Biotechnology Clene Inc. Portfolio share: 0.10% Portfolio value: 496K Avg. open price: $10.79 Current price: $1.09 P/L: -89.89% N/A Q3 2022	put	0.10%	496K	$10.79	$1.09	-89.89%	N/A Q3 2022
Biotechnology Immatics N.V. Portfolio share: 0.10% Portfolio value: 490K Avg. open price: $11.68 Current price: $11.13 P/L: -4.74% Sold -68.81% shares Q3 2022	share	0.10%	490K	$11.68	$11.13	-4.74%	Sold -68.81% shares Q3 2022
Biotechnology Reata Pharmaceuticals, Inc. Portfolio share: 0.09% Portfolio value: 463K Avg. open price: $69.69 Current price: $39.62 P/L: -43.15% N/A Q3 2022	put	0.09%	463K	$69.69	$39.62	-43.15%	N/A Q3 2022
Biotechnology Anebulo Pharmaceuticals, Inc. Portfolio share: 0.09% Portfolio value: 437K Avg. open price: $6.15 Current price: $2.65 P/L: -56.91% Sold -13.79% shares Q3 2022	share	0.09%	437K	$6.15	$2.65	-56.91%	Sold -13.79% shares Q3 2022
Biotechnology Clovis Oncology, Inc. Portfolio share: 0.09% Portfolio value: 430K Avg. open price: $7.2 Current price: $0.29 P/L: -95.95% Sold -14.40% shares Q3 2022	share	0.09%	430K	$7.2	$0.29	-95.95%	Sold -14.40% shares Q3 2022
Biotechnology Finch Therapeutics Group, Inc. Portfolio share: 0.08% Portfolio value: 397K Avg. open price: $15.68 Current price: $0.95 P/L: -93.94% Sold -28.13% shares Q3 2022	share	0.08%	397K	$15.68	$0.95	-93.94%	Sold -28.13% shares Q3 2022
Biotechnology Synlogic, Inc. Portfolio share: 0.06% Portfolio value: 292K Avg. open price: $2.39 Current price: $0.74 P/L: -69.04% Sold -35.33% shares Q3 2022	share	0.06%	292K	$2.39	$0.74	-69.04%	Sold -35.33% shares Q3 2022
Biotechnology Connect Biopharma Holdings Limited Portfolio share: 0.06% Portfolio value: 283K Avg. open price: $5.04 Current price: $0.71 P/L: -85.87% Sold -67.62% shares Q3 2022	share	0.06%	283K	$5.04	$0.71	-85.87%	Sold -67.62% shares Q3 2022
Biotechnology Gossamer Bio, Inc. Portfolio share: 0.04% Portfolio value: 209K Avg. open price: $10.34 Current price: $9.29 P/L: -10.15% N/A Q3 2022	put	0.04%	209K	$10.34	$9.29	-10.15%	N/A Q3 2022
Biotechnology Verona Pharma plc Portfolio share: 0.04% Portfolio value: 193K Avg. open price: $4.19 Current price: $13.57 P/L: +223.87% Bought +5.04% shares Q3 2022	share	0.04%	193K	$4.19	$13.57	+223.87%	Bought +5.04% shares Q3 2022
ARK Innovation ETF Portfolio share: 0.03% Portfolio value: 171K Avg. open price: N/A Current price: $36.07 P/L: N/A N/A Q3 2022	share	0.03%	171K	N/A	$36.07	N/A	N/A Q3 2022
Biotechnology Praxis Precision Medicines, Inc. Portfolio share: 0.03% Portfolio value: 168K Avg. open price: N/A Current price: $2.14 P/L: N/A Sold -30.78% shares Q3 2022	call	0.03%	168K	N/A	$2.14	N/A	Sold -30.78% shares Q3 2022
Biotechnology ASLAN Pharmaceuticals Limited Portfolio share: 0.03% Portfolio value: 146K Avg. open price: $2.83 Current price: $0.53 P/L: -81.15% Sold -15.48% shares Q3 2022	share	0.03%	146K	$2.83	$0.53	-81.15%	Sold -15.48% shares Q3 2022
Biotechnology Stealth BioTherapeutics Corp Portfolio share: 0.03% Portfolio value: 134K Avg. open price: $1.47 Current price: $0.32 P/L: -78.29% Sold -13.22% shares Q3 2022	share	0.03%	134K	$1.47	$0.32	-78.29%	Sold -13.22% shares Q3 2022
Biotechnology Cabaletta Bio, Inc. Portfolio share: 0.02% Portfolio value: 109K Avg. open price: $9.79 Current price: $4.97 P/L: -49.23% Sold -82.15% shares Q3 2022	share	0.02%	109K	$9.79	$4.97	-49.23%	Sold -82.15% shares Q3 2022
Biotechnology Reata Pharmaceuticals, Inc. Portfolio share: 0.02% Portfolio value: 102K Avg. open price: $69.69 Current price: $39.62 P/L: -43.15% Sold -80.47% shares Q3 2022	share	0.02%	102K	$69.69	$39.62	-43.15%	Sold -80.47% shares Q3 2022
Biotechnology Spectrum Pharmaceuticals, Inc. Portfolio share: 0.02% Portfolio value: 76K Avg. open price: N/A Current price: $0.47 P/L: N/A N/A Q3 2022	share	0.02%	76K	N/A	$0.47	N/A	N/A Q3 2022
Biotechnology Corbus Pharmaceuticals Holdings, Inc. Portfolio share: 0.01% Portfolio value: 66K Avg. open price: $1.21 Current price: $0.13 P/L: -89.37% Sold -53.95% shares Q3 2022	share	0.01%	66K	$1.21	$0.13	-89.37%	Sold -53.95% shares Q3 2022
Biotechnology Inventiva S.A. Portfolio share: 0.01% Portfolio value: 48K Avg. open price: $13.81 Current price: $4.45 P/L: -67.79% Sold -15.04% shares Q3 2022	share	0.01%	48K	$13.81	$4.45	-67.79%	Sold -15.04% shares Q3 2022
Biotechnology ERYTECH Pharma S.A. Portfolio share: 0.00% Portfolio value: 2K Avg. open price: N/A Current price: $0.59 P/L: N/A N/A Q3 2022	share	0.00%	2K	N/A	$0.59	N/A	N/A Q3 2022
Biotechnology Adicet Bio, Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: $10.23 Current price: $20.2 P/L: +97.37% Sold -100.00% shares Q3 2022	share	0.00%	0	$10.23	$20.2	+97.37%	Sold -100.00% shares Q3 2022
Biotechnology United Therapeutics Corporation Portfolio share: 0.00% Portfolio value: 0 Avg. open price: $151.79 Current price: $273.72 P/L: +80.33% Sold -100.00% shares Q3 2022	share	0.00%	0	$151.79	$273.72	+80.33%	Sold -100.00% shares Q3 2022
Biotechnology Vaxcyte, Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: $38.25 Current price: $44.33 P/L: +15.90% Sold -100.00% shares Q3 2022	share	0.00%	0	$38.25	$44.33	+15.90%	Sold -100.00% shares Q3 2022
Biotechnology Verastem, Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: $1.54 Current price: $0.42 P/L: -72.77% Sold -100.00% shares Q3 2022	share	0.00%	0	$1.54	$0.42	-72.77%	Sold -100.00% shares Q3 2022
Biotechnology Vertex Pharmaceuticals Incorporated Portfolio share: 0.00% Portfolio value: 0 Avg. open price: $260.97 Current price: $317.6 P/L: +21.70% Sold -100.00% shares Q3 2022	share	0.00%	0	$260.97	$317.6	+21.70%	Sold -100.00% shares Q3 2022
Biotechnology Viridian Therapeutics, Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: N/A Current price: $26.84 P/L: N/A Sold -100.00% shares Q3 2022	call	0.00%	0	N/A	$26.84	N/A	Sold -100.00% shares Q3 2022
Biotechnology Yumanity Therapeutics, Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: $15.51 Current price: $2.05 P/L: -86.81% Sold -100.00% shares Q3 2022	share	0.00%	0	$15.51	$2.05	-86.81%	Sold -100.00% shares Q3 2022
Biotechnology Zai Lab Limited Portfolio share: 0.00% Portfolio value: 0 Avg. open price: $66.92 Current price: $33.74 P/L: -49.58% Sold -100.00% shares Q3 2022	share	0.00%	0	$66.92	$33.74	-49.58%	Sold -100.00% shares Q3 2022
Biotechnology Altamira Therapeutics Ltd. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: $1.93 Current price: $5.74 P/L: +197.15% Sold -100.00% shares Q3 2022	share	0.00%	0	$1.93	$5.74	+197.15%	Sold -100.00% shares Q3 2022
Biotechnology Vascular Biogenics Ltd. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: $1.93 Current price: $0.16 P/L: -91.89% Sold -100.00% shares Q3 2022	share	0.00%	0	$1.93	$0.16	-91.89%	Sold -100.00% shares Q3 2022
Biotechnology Merus N.V. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: $32.29 Current price: $14.2 P/L: -56.02% Sold -100.00% shares Q3 2022	share	0.00%	0	$32.29	$14.2	-56.02%	Sold -100.00% shares Q3 2022
Biotechnology BioMarin Pharmaceutical Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: $88.54 Current price: $103.53 P/L: +16.92% Sold -100.00% shares Q3 2022	share	0.00%	0	$88.54	$103.53	+16.92%	Sold -100.00% shares Q3 2022
Biotechnology Wave Life Sciences Ltd. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: $3.28 Current price: $4.25 P/L: +29.57% Sold -100.00% shares Q3 2022	share	0.00%	0	$3.28	$4.25	+29.57%	Sold -100.00% shares Q3 2022
Biotechnology Blueprint Medicines Corporation Portfolio share: 0.00% Portfolio value: 0 Avg. open price: $58.48 Current price: $50.19 P/L: -14.18% Sold -100.00% shares Q3 2022	call	0.00%	0	$58.48	$50.19	-14.18%	Sold -100.00% shares Q3 2022
Biotechnology BridgeBio Pharma, Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: N/A Current price: $9.17 P/L: N/A Sold -100.00% shares Q3 2022	call	0.00%	0	N/A	$9.17	N/A	Sold -100.00% shares Q3 2022
Biotechnology Bright Minds Biosciences Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: $3.31 Current price: $1.09 P/L: -67.07% Sold -100.00% shares Q3 2022	share	0.00%	0	$3.31	$1.09	-67.07%	Sold -100.00% shares Q3 2022
Biotechnology CASI Pharmaceuticals, Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: $2.23 Current price: $1.94 P/L: -12.86% Sold -100.00% shares Q3 2022	share	0.00%	0	$2.23	$1.94	-12.86%	Sold -100.00% shares Q3 2022
Biotechnology Celldex Therapeutics, Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: $30.96 Current price: $36.66 P/L: +18.42% Sold -100.00% shares Q3 2022	call	0.00%	0	$30.96	$36.66	+18.42%	Sold -100.00% shares Q3 2022
Biotechnology Celldex Therapeutics, Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: $30.96 Current price: $36.66 P/L: +18.42% Sold -100.00% shares Q3 2022	put	0.00%	0	$30.96	$36.66	+18.42%	Sold -100.00% shares Q3 2022
Biotechnology BioMarin Pharmaceutical Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: $88.54 Current price: $103.53 P/L: +16.92% Sold -100.00% shares Q3 2022	call	0.00%	0	$88.54	$103.53	+16.92%	Sold -100.00% shares Q3 2022
Biotechnology Chimerix, Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: $4.79 Current price: $2.22 P/L: -53.68% Sold -100.00% shares Q3 2022	share	0.00%	0	$4.79	$2.22	-53.68%	Sold -100.00% shares Q3 2022
Biotechnology Clene Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: $10.79 Current price: $1.09 P/L: -89.89% Sold -100.00% shares Q3 2022	share	0.00%	0	$10.79	$1.09	-89.89%	Sold -100.00% shares Q3 2022
Biotechnology ContraFect Corporation Portfolio share: 0.00% Portfolio value: 0 Avg. open price: N/A Current price: $0.14 P/L: N/A Sold -100.00% shares Q3 2022	put	0.00%	0	N/A	$0.14	N/A	Sold -100.00% shares Q3 2022
Biotechnology Cyclacel Pharmaceuticals, Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: $3.88 Current price: $0.77 P/L: -80.15% Sold -100.00% shares Q3 2022	share	0.00%	0	$3.88	$0.77	-80.15%	Sold -100.00% shares Q3 2022
Biotechnology DBV Technologies S.A. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: $5.62 Current price: $1.31 P/L: -76.69% Sold -100.00% shares Q3 2022	share	0.00%	0	$5.62	$1.31	-76.69%	Sold -100.00% shares Q3 2022
Biotechnology Baudax Bio, Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: N/A Current price: $3.7 P/L: N/A Sold -100.00% shares Q3 2022	share	0.00%	0	N/A	$3.7	N/A	Sold -100.00% shares Q3 2022
Biotechnology Ayala Pharmaceuticals, Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: $10.74 Current price: $0.62 P/L: -94.23% Sold -100.00% shares Q3 2022	share	0.00%	0	$10.74	$0.62	-94.23%	Sold -100.00% shares Q3 2022
Biotechnology Enveric Biosciences, Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: $0.93 Current price: $3 P/L: +221.85% Sold -100.00% shares Q3 2022	share	0.00%	0	$0.93	$3	+221.85%	Sold -100.00% shares Q3 2022
Biotechnology Axsome Therapeutics, Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: $103.36 Current price: $77.29 P/L: -25.22% Sold -100.00% shares Q3 2022	call	0.00%	0	$103.36	$77.29	-25.22%	Sold -100.00% shares Q3 2022
Drug Manufacturers—Specialty & Generic Evolus, Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: N/A Current price: $6.98 P/L: N/A Sold -100.00% shares Q3 2022	share	0.00%	0	N/A	$6.98	N/A	Sold -100.00% shares Q3 2022
Biotechnology Fulcrum Therapeutics, Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: N/A Current price: $6.56 P/L: N/A Sold -100.00% shares Q3 2022	call	0.00%	0	N/A	$6.56	N/A	Sold -100.00% shares Q3 2022
Biotechnology Galapagos NV Portfolio share: 0.00% Portfolio value: 0 Avg. open price: N/A Current price: $38.92 P/L: N/A Sold -100.00% shares Q3 2022	share	0.00%	0	N/A	$38.92	N/A	Sold -100.00% shares Q3 2022
Biotechnology Gemini Therapeutics, Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: $3.02 Current price: $1.7 P/L: -43.71% Sold -100.00% shares Q3 2022	share	0.00%	0	$3.02	$1.7	-43.71%	Sold -100.00% shares Q3 2022
Biotechnology Athira Pharma, Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: $9.38 Current price: $2.94 P/L: -68.66% Sold -100.00% shares Q3 2022	put	0.00%	0	$9.38	$2.94	-68.66%	Sold -100.00% shares Q3 2022
Biotechnology Harmony Biosciences Holdings, Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: N/A Current price: $60.91 P/L: N/A Sold -100.00% shares Q3 2022	share	0.00%	0	N/A	$60.91	N/A	Sold -100.00% shares Q3 2022
Biotechnology Hepion Pharmaceuticals, Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: $1.17 Current price: $0.38 P/L: -67.43% Sold -100.00% shares Q3 2022	share	0.00%	0	$1.17	$0.38	-67.43%	Sold -100.00% shares Q3 2022
Biotechnology ImmunoPrecise Antibodies Ltd. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: $5.45 Current price: $5.46 P/L: +0.18% Sold -100.00% shares Q3 2022	share	0.00%	0	$5.45	$5.46	+0.18%	Sold -100.00% shares Q3 2022
Biotechnology Aadi Bioscience, Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: $22.93 Current price: $13.42 P/L: -41.49% Sold -100.00% shares Q3 2022	share	0.00%	0	$22.93	$13.42	-41.49%	Sold -100.00% shares Q3 2022
Biotechnology Immunic, Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: N/A Current price: $1.34 P/L: N/A Sold -100.00% shares Q3 2022	put	0.00%	0	N/A	$1.34	N/A	Sold -100.00% shares Q3 2022
Biotechnology Immunic, Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: N/A Current price: $1.34 P/L: N/A Sold -100.00% shares Q3 2022	share	0.00%	0	N/A	$1.34	N/A	Sold -100.00% shares Q3 2022
Biotechnology Inhibrx, Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: $28.2 Current price: $29.18 P/L: +3.46% Sold -100.00% shares Q3 2022	share	0.00%	0	$28.2	$29.18	+3.46%	Sold -100.00% shares Q3 2022
Biotechnology Insmed Incorporated Portfolio share: 0.00% Portfolio value: 0 Avg. open price: $23.88 Current price: $19.89 P/L: -16.71% Sold -100.00% shares Q3 2022	share	0.00%	0	$23.88	$19.89	-16.71%	Sold -100.00% shares Q3 2022
Biotechnology Intercept Pharmaceuticals, Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: $43.66 Current price: $14.32 P/L: -67.20% Sold -100.00% shares Q3 2022	call	0.00%	0	$43.66	$14.32	-67.20%	Sold -100.00% shares Q3 2022
Biotechnology iTeos Therapeutics, Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: N/A Current price: $20.04 P/L: N/A Sold -100.00% shares Q3 2022	call	0.00%	0	N/A	$20.04	N/A	Sold -100.00% shares Q3 2022
Biotechnology Athira Pharma, Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: $9.38 Current price: $2.94 P/L: -68.66% Sold -100.00% shares Q3 2022	call	0.00%	0	$9.38	$2.94	-68.66%	Sold -100.00% shares Q3 2022
Biotechnology Karuna Therapeutics, Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: $126.79 Current price: $226.95 P/L: +79.00% Sold -100.00% shares Q3 2022	put	0.00%	0	$126.79	$226.95	+79.00%	Sold -100.00% shares Q3 2022
Biotechnology Karuna Therapeutics, Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: $126.79 Current price: $226.95 P/L: +79.00% Sold -100.00% shares Q3 2022	share	0.00%	0	$126.79	$226.95	+79.00%	Sold -100.00% shares Q3 2022
Biotechnology Kezar Life Sciences, Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: $16.58 Current price: $7.07 P/L: -57.37% Sold -100.00% shares Q3 2022	call	0.00%	0	$16.58	$7.07	-57.37%	Sold -100.00% shares Q3 2022
KraneShares CSI China Internet ETF Portfolio share: 0.00% Portfolio value: 0 Avg. open price: N/A Current price: $29.78 P/L: N/A Sold -100.00% shares Q3 2022	share	0.00%	0	N/A	$29.78	N/A	Sold -100.00% shares Q3 2022
Biotechnology Arcus Biosciences, Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: $25.96 Current price: $33.96 P/L: +30.82% Sold -100.00% shares Q3 2022	put	0.00%	0	$25.96	$33.96	+30.82%	Sold -100.00% shares Q3 2022
Drug Manufacturers—Specialty & Generic Lantheus Holdings, Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: N/A Current price: $56.01 P/L: N/A Sold -100.00% shares Q3 2022	call	0.00%	0	N/A	$56.01	N/A	Sold -100.00% shares Q3 2022
Biotechnology Larimar Therapeutics, Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: $10.89 Current price: $3.15 P/L: -71.07% Sold -100.00% shares Q3 2022	share	0.00%	0	$10.89	$3.15	-71.07%	Sold -100.00% shares Q3 2022
Biotechnology Mereo BioPharma Group plc Portfolio share: 0.00% Portfolio value: 0 Avg. open price: $1.61 Current price: $0.83 P/L: -48.30% Sold -100.00% shares Q3 2022	share	0.00%	0	$1.61	$0.83	-48.30%	Sold -100.00% shares Q3 2022
Biotechnology Arcus Biosciences, Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: $25.96 Current price: $33.96 P/L: +30.82% Sold -100.00% shares Q3 2022	call	0.00%	0	$25.96	$33.96	+30.82%	Sold -100.00% shares Q3 2022
Biotechnology Mind Medicine (MindMed) Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: $1.43 Current price: $2.83 P/L: +97.90% Sold -100.00% shares Q3 2022	share	0.00%	0	$1.43	$2.83	+97.90%	Sold -100.00% shares Q3 2022
Biotechnology MUSTANG BIO INC Portfolio share: 0.00% Portfolio value: 0 Avg. open price: $3.12 Current price: $0.47 P/L: -84.91% Sold -100.00% shares Q3 2022	share	0.00%	0	$3.12	$0.47	-84.91%	Sold -100.00% shares Q3 2022
Biotechnology MyMD Pharmaceuticals, Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: $5.46 Current price: $1.95 P/L: -64.29% Sold -100.00% shares Q3 2022	share	0.00%	0	$5.46	$1.95	-64.29%	Sold -100.00% shares Q3 2022
Drug Manufacturers—Specialty & Generic Neurocrine Biosciences, Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: $107.49 Current price: $124 P/L: +15.36% Sold -100.00% shares Q3 2022	share	0.00%	0	$107.49	$124	+15.36%	Sold -100.00% shares Q3 2022
Biotechnology NextCure, Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: $10.62 Current price: $1.4 P/L: -86.82% Sold -100.00% shares Q3 2022	share	0.00%	0	$10.62	$1.4	-86.82%	Sold -100.00% shares Q3 2022
Biotechnology Ovid Therapeutics Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: $3.62 Current price: $1.79 P/L: -50.49% Sold -100.00% shares Q3 2022	share	0.00%	0	$3.62	$1.79	-50.49%	Sold -100.00% shares Q3 2022
Biotechnology Pardes Biosciences, Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: N/A Current price: $1.1 P/L: N/A Sold -100.00% shares Q3 2022	share	0.00%	0	N/A	$1.1	N/A	Sold -100.00% shares Q3 2022
Drug Manufacturers—General Pfizer Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: N/A Current price: $50.73 P/L: N/A Sold -100.00% shares Q3 2022	share	0.00%	0	N/A	$50.73	N/A	Sold -100.00% shares Q3 2022
Biotechnology Apellis Pharmaceuticals, Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: $43.88 Current price: $49.41 P/L: +12.58% Sold -100.00% shares Q3 2022	share	0.00%	0	$43.88	$49.41	+12.58%	Sold -100.00% shares Q3 2022
Biotechnology Regulus Therapeutics Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: $0.33 Current price: $1.74 P/L: +433.09% Sold -100.00% shares Q3 2022	share	0.00%	0	$0.33	$1.74	+433.09%	Sold -100.00% shares Q3 2022
Biotechnology Apellis Pharmaceuticals, Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: $43.88 Current price: $49.41 P/L: +12.58% Sold -100.00% shares Q3 2022	call	0.00%	0	$43.88	$49.41	+12.58%	Sold -100.00% shares Q3 2022
Biotechnology Rigel Pharmaceuticals, Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: $2.44 Current price: $0.95 P/L: -61.11% Sold -100.00% shares Q3 2022	share	0.00%	0	$2.44	$0.95	-61.11%	Sold -100.00% shares Q3 2022
Biotechnology Amylyx Pharmaceuticals, Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: $12.85 Current price: $38.55 P/L: +200.00% Sold -100.00% shares Q3 2022	share	0.00%	0	$12.85	$38.55	+200.00%	Sold -100.00% shares Q3 2022
Drug Manufacturers—General Amgen Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: N/A Current price: $285.01 P/L: N/A Sold -100.00% shares Q3 2022	call	0.00%	0	N/A	$285.01	N/A	Sold -100.00% shares Q3 2022
Biotechnology Sage Therapeutics, Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: $55.04 Current price: $43.52 P/L: -20.92% Sold -100.00% shares Q3 2022	call	0.00%	0	$55.04	$43.52	-20.92%	Sold -100.00% shares Q3 2022
Biotechnology Alnylam Pharmaceuticals, Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: $163.29 Current price: $226.4 P/L: +38.65% Sold -100.00% shares Q3 2022	put	0.00%	0	$163.29	$226.4	+38.65%	Sold -100.00% shares Q3 2022
Biotechnology Alnylam Pharmaceuticals, Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: $163.29 Current price: $226.4 P/L: +38.65% Sold -100.00% shares Q3 2022	call	0.00%	0	$163.29	$226.4	+38.65%	Sold -100.00% shares Q3 2022
Biotechnology Aldeyra Therapeutics, Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: N/A Current price: $6.46 P/L: N/A Sold -100.00% shares Q3 2022	share	0.00%	0	N/A	$6.46	N/A	Sold -100.00% shares Q3 2022
Biotechnology Synaptogenix, Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: $8.77 Current price: $6.04 P/L: -31.13% Sold -100.00% shares Q3 2022	share	0.00%	0	$8.77	$6.04	-31.13%	Sold -100.00% shares Q3 2022
Biotechnology Tempest Therapeutics, Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: $5.46 Current price: $1.65 P/L: -69.78% Sold -100.00% shares Q3 2022	share	0.00%	0	$5.46	$1.65	-69.78%	Sold -100.00% shares Q3 2022
Biotechnology Aileron Therapeutics, Inc. Portfolio share: 0.00% Portfolio value: 0 Avg. open price: $0.54 Current price: $2.79 P/L: +420.91% Sold -100.00% shares Q3 2022	share	0.00%	0	$0.54	$2.79	+420.91%	Sold -100.00% shares Q3 2022

Showing TOP 178 IKARIAN CAPITAL's 13F holdings.

Frequently Asked Questions (FAQ)

What is the biggest position of IKARIAN CAPITAL, LLC?

The biggest position of the IKARIAN CAPITAL, LLC is Relmada Therapeutics, Inc. (RLMD) with 5.72% portfolio share worth of 28.7M US dollars.

Top 5 IKARIAN CAPITAL's holdings represent 23.55% of the portfolio:

Relmada Therapeutics, Inc. (RLMD) – 5.72%
Relmada Therapeutics, Inc. (RLMD) – 5.72%
SPDR S&P 500 ETF Trust (SPY) – 4.27%
Seagen Inc. (SGEN) – 4.09%
Biogen Inc. (BIIB) – 3.75%

Who is the portfolio manager of IKARIAN CAPITAL, LLC?

The portfolio manager of the IKARIAN CAPITAL, LLC is .

What is the total asset value of the IKARIAN CAPITAL, LLC portfolio?

IKARIAN CAPITAL, LLC total asset value (portfolio value) is 501.84M US dollars.

Who is ?

is the portfolio manager of the IKARIAN CAPITAL, LLC.

What is (IKARIAN CAPITAL, LLC) fund performance?

IKARIAN CAPITAL's quarterly performance is +15.48%, annualy -29.21%.

What is the IKARIAN CAPITAL, LLC CIK?

IKARIAN CAPITAL's Central Index Key is 0001778253 .