Alnylam Pharmaceuticals, Inc.
Angiotensinogen (AGT) iRNA compositions and methods of use thereof

Abstract:

The present invention relates to RNAi agents, e.g., double stranded RNA (dsRNA) agents, targeting the AGT gene. The invention also relates to methods of using such RNAi agents to inhibit expression of an AGT gene and to methods of preventing and treating an AGT-associated disorder, e.g., high blood pressure.