Alnylam Pharmaceuticals, Inc.
Polynucleotide agents targeting hydroxyacid oxidase (glycolate oxidase, HAO1) and methods of use thereof
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Abstract:
The invention relates to polynucleotide agents targeting an hydroxyacid oxidase (HAO1) gene, and methods of using such polynucleotide agents to inhibit expression of HAO1 and to treat subjects having an HAO1-associated disease, e.g., hyperoxaluria.
Status:
Grant
Type:
Utility
Filling date:
14 Dec 2017
Issue date:
16 Mar 2021