Alnylam Pharmaceuticals, Inc.
Glucokinase (GCK) iRNA compositions and methods of use thereof

Abstract:

The invention relates to double stranded ribonucleic acid (dsRNA) compositions targeting a glucokinase (GCK) gene, as well as methods of inhibiting expression of a glucokinase (GCK) gene, and methods of treating subjects having a glycogen storage disease (GSD), e.g., type Ia GSD.