Alnylam Pharmaceuticals, Inc.
Polynucleotide agents targeting angiotensinogen (AGT) and methods of use thereof

Abstract:

The invention relates to polynucleotide agents, e.g., antisense polynucleotide agents, targeting an angiotensinogen (AGT) gene, and methods of using such polynucleotide agents to inhibit expression of AGT and to treat subjects having an AGT-associated disease, e.g., hypertension.