Alnylam Pharmaceuticals, Inc.
QUANTIFICATION OF TRANSTHYRETIN AND ITS ISOFORMS

Abstract:

The present invention relates to assays and methods for the detection of transthyretin and its isoforms. Specifically, the assays and methods of the present invention embrace liquid chromatography and mass spectrometry. The present invention also relates to unique peptides and peptide variants useful in the assays and methods.