Alnylam Pharmaceuticals, Inc.
SERPINA1 iRNA COMPOSITIONS AND METHODS OF USE THEREOF

Abstract:

The invention relates to RNAi agents, e.g., double stranded RNAi agents, targeting the Serpina1 gene, and methods of using such RNAi agents to inhibit expression of Serpina1 and methods of treating subjects having a Serpina1 associated disease, such as a liver disorder.