Intellia Therapeutics, Inc.
Stabilized Nucleic Acids Encoding Messenger Ribonucleic Acid (mRNA)

Abstract:

This disclosure relates to the field of poly-adenylated (poly-A) tails. In some embodiments, a DNA encodes a poly-A tail located 3' to nucleotides encoding a protein of interest, wherein the poly-A tail comprises one or more non-adenine nucleotide.