Ionis Pharmaceuticals, Inc.
MODULATION OF THE NOTCH SIGNALING PATHWAY FOR TREATMENT OF RESPIRATORY DISORDERS

Abstract:

Provided herein are methods, compounds, and compositions for modulating expression of at least one member of the Notch signaling pathway in a cell or individual. Such methods, compounds, and compositions are useful to treat, prevent, delay, or ameliorate a respiratory disorder associated with excessive mucus production in an individual.