Myriad Genetics, Inc.
METHODS AND SYSTEMS FOR SOMATIC MUTATIONS AND USES THEREOF

Abstract:

This invention provides methods and compositions for detecting somatic mutations in cancer cells. The methods can be used for measuring tumor mutation burden. Provided are methods for identifying and treating subjects who benefit from treatment with anticancer agents such as immune checkpoint inhibitors, methods for treating cancer in a subject, and methods for monitoring and prognosing a subject having cancer.