Sorrento Therapeutics, Inc.
DRUG DELIVERY METHODS TARGETING THE LYMPHATIC SYSTEM

Abstract:

Disclosed herein is a method for administering a therapeutic agent to multiple regions of the lymphatic system of a patient. The method generally includes placing two medical devices comprising a plurality of microneedles on the skin of the patient at two different locations proximate lymph vessels and/or lymph capillaries that drain into the right lymphatic duct and the thoracic duct; inserting the plurality of microneedles of medical devices into the patient to a depth whereby at least the epidermis is penetrated and administering via the microneedles of the medical devices a therapeutic agent into the lymphatic system of the patient. Disclosed herein also is a method for preventing or reducing cancer metastasis in a patient. Disclosed herein also is a method for treating an inflammatory medical condition in a patient.