Alexion Pharmaceuticals, Inc.
ANTI-ALK2 ANTIBODIES AND USES THEREOF

Abstract:

Provided herein are antibodies that bind to activin receptor--like kinase 2 (ALK2) and are useful for treating bone disorders, such as those involving reduced bone mineral density and bone mineralization defects, and promoting bone growth. Also provided are polynucleotides encoding the antibodies, vectors comprising the polynucleotides, and cells that produce the antibodies.