Alexion Pharmaceuticals, Inc.
COMPOSITIONS AND METHODS FOR THE TREATMENT OF NEUROMYELITIS OPTICA

Abstract:

Provided are methods of treating neuromyelitis optica spectrum disorder (NMOSD) in a subject in need thereof by administering to the subject a substance that specifically binds complement component 5 (C5). In some embodiments, the substance that specifically binds C5 is a binding protein, e.g., an anti-C5 antibody.