Regeneron Pharmaceuticals, Inc.
Methods for increasing lean body mass with resistance training and a GDF8 inhibitor that is an anti-GDF8 antibody

Abstract:

The disclosure provides compositions, kits, and methods of using a GDF-8 inhibitor to increase lean muscle mass. In embodiments, a GDF-8 inhibitor is an antibody or antigen binding fragment thereof that specifically binds GDF-8. In embodiments, a method comprises providing an exercise regimen for the subject, and administering a composition comprising an effective amount of a GDF-8 inhibitor.