Regeneron Pharmaceuticals, Inc.
Methods for treating allergy and enhancing allergen-specific immunotherapy by administering an antibody to IL-4 receptor

Abstract:

The present invention provides methods for treating, preventing or reducing the severity of allergic reactions. The present invention also provides methods for enhancing the efficacy and/or safety of an allergen-specific immunotherapy (SIT) regimen. The methods of the present invention comprise administering to a subject in need thereof a therapeutic composition comprising an interleukin-4 receptor (IL-4R.alpha.) antagonist such as an anti-IL-4R.alpha. antibody.