Regeneron Pharmaceuticals, Inc.
RODENTS HAVING A HUMANIZED TMPRSS GENE

Abstract:

Genetically modified rodents such as mice and rats, and methods and compositions for making and using the same, are provided. The rodents comprise a humanization of at least one endogenous rodent Tmprss gene, such as an endogenous rodent Tmprss2, Tmprss4, or Tmprss11d gene.