Regeneron Pharmaceuticals, Inc.
Anti-PfRH5 Antibodies and Antigen-Binding Fragments Thereof

Abstract:

The present invention includes antibodies and antigen-binding fragments thereof that specifically bind to Plasmodium falciparum reticulocyte binding protein homologue 5 (PfRH5), compositions thereof and methods of making such antibodies, fragments and compositions. Method and compositions for treating, preventing or diagnosing Plasmodium falciparum infection and malaria are also part of the present invention.