Agilent Technologies, Inc.
RAMAN ANALYSIS OF PHARMACEUTICAL DOSAGE FORMS

Abstract:

There are disclosed methods and apparatus for automatic analysis of pharmaceutical dosage forms. In some aspects a dosage form may be grasped by a gripper which is used to bring the dosage form to a test location and to present the dosage form in a plurality of different alignments between delivery and collection optics. Probe light scattered through the dosage form is collected during each alignment. The collected probe light for the plurality of alignments is then used for Raman spectral analysis of the dosage form. In other aspects a rotation stage is used to rotate a dosage form on the stage to a preferred alignment before being grasped by a gripper. The gripper is then used to carry the dosage form to the test location for optical analysis.