Abcam plc
METHODS AND COMPOSITIONS FOR LIGAND DIRECTED ANTIBODY DESIGN

Abstract:

The present disclosure provides, among other things, methods for generating antibodies against a target protein. In some embodiments, a library is provided comprising a plurality of tether antibodies comprising an antigen binding region and a ligand that binds to a target protein. In some embodiments, a library is provided comprising a plurality of candidate antibodies for binding to a target protein.