Aclaris Therapeutics, Inc.
PYRROLOPYRIMIDINE ITK INHIBITORS

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Abstract:

Disclosed herein are arylpyridinone compounds and compositions useful in the treatment of ITK mediated diseases, such as inflammation, having the structures of Formulas (I)-(IV): ##STR00001## wherein the R groups, m, n, and X are as defined in the detailed description. Methods of inhibition of ITK activity in a human or animal subject are also provided.

Status:
Application
Type:

Utility

Filling date:

12 Aug 2019

Issue date:

13 Feb 2020