Aclaris Therapeutics, Inc.
Substituted pyrrolopyridine JAK inhibitors and methods of making and using the same

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Abstract:

The present invention relates to new pyrrolopyridine compounds and compositions and their application as pharmaceuticals for the treatment of disease. Methods of inhibition of JAK1 and JAK3 kinase activity in a human or animal subject are also provided for the treatment diseases such as pruritus, alopecia, androgenetic alopecia, alopecia areata, vitiligo and psoriasis.

Status:
Grant
Type:

Utility

Filling date:

2 Nov 2018

Issue date:

20 Apr 2021