Aclaris Therapeutics, Inc.
Substituted pyrrolopyridine JAK inhibitors and methods of making and using the same
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Abstract:
The present invention relates to new pyrrolopyridine compounds and compositions and their application as pharmaceuticals for the treatment of disease. Methods of inhibition of JAK1 and JAK3 kinase activity in a human or animal subject are also provided for the treatment diseases such as pruritus, alopecia, androgenetic alopecia, alopecia areata, vitiligo and psoriasis.
Status:
Grant
Type:
Utility
Filling date:
2 Nov 2018
Issue date:
20 Apr 2021