Allakos Inc.
METHODS AND COMPOSITIONS FOR TREATING MAST CELL GASTRITIS, MAST CELL ESOPHAGITIS, MAST CELL ENTERITIS, MAST CELL DUODENITIS, AND/OR MAST CELL GASTROENTERITIS
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Abstract:
The present disclosure provides methods for the treatment of mast cell gastritis, mast cell esophagitis, mast cell colitis, mast cell enteritis, mast cell duodenitis, and/or mast cell gastroenteritis. In particular, the present disclosure provides methods for the treatment of mast cell gastritis, mast cell esophagitis, mast cell colitis, mast cell enteritis, mast cell duodenitis, and/or mast cell gastroenteritis through administration of antibodies that bind to human Siglec-8 or compositions comprising said antibodies. The present disclosure also provides articles of manufacture or kits comprising antibodies that bind to human Siglec-8 for the treatment of mast cell gastritis, mast cell esophagitis, mast cell colitis, mast cell enteritis, mast cell duodenitis, and/or mast cell gastroenteritis.
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14 Feb 2020
5 May 2022