Allogene Therapeutics, Inc.
CONSTITUTIVELY ACTIVE CHIMERIC CYTOKINE RECEPTORS
Last updated:
Abstract:
Provided herein are constitutively active chimeric cytokine receptors (CACCRs). When present on chimeric antigen receptor (CAR)-bearing immune cells, such CACCRs allow for increased immune cell activation, proliferation, persistence, and/or potency. Also provided are methods of making and using the CACCRs described herein.
Status:
Application
Type:
Utility
Filling date:
28 Feb 2020
Issue date:
17 Sep 2020