Allogene Therapeutics, Inc.
CONSTITUTIVELY ACTIVE CHIMERIC CYTOKINE RECEPTORS

Last updated:

Abstract:

Provided herein are constitutively active chimeric cytokine receptors (CACCRs). When present on chimeric antigen receptor (CAR)-bearing immune cells, such CACCRs allow for increased immune cell activation, proliferation, persistence, and/or potency. Also provided are methods of making and using the CACCRs described herein.

Status:
Application
Type:

Utility

Filling date:

28 Feb 2020

Issue date:

17 Sep 2020