Allogene Therapeutics, Inc.
Modified caspase-9 polypeptides and methods of use thereof

Last updated:

Abstract:

Provided herein are modified caspase-9 polypeptides, and chimeric caspase-9 proteins containing the modified caspase-9 polypeptides. The disclosure further provides polynucleotides encoding these proteins, engineered host cells containing these polynucleotides and proteins, including host cells that co-express a chimeric antigen receptor, and methods of making and using the same.

Status:
Grant
Type:

Utility

Filling date:

31 Oct 2018

Issue date:

10 May 2022