Allogene Therapeutics, Inc.
MODIFIED CASPASE-9 POLYPEPTIDES AND METHODS OF USE THEREOF

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Abstract:

Provided herein are modified caspase-9 polypeptides, and chimeric caspase-9 proteins containing the modified caspase-9 polypeptides. The disclosure further provides polynucleotides encoding these proteins, engineered host cells containing these polynucleotides and proteins, including host cells that co-express a chimeric antigen receptor, and methods of making and using the same.

Status:
Application
Type:

Utility

Filling date:

8 Apr 2022

Issue date:

28 Jul 2022