Alpine Immune Sciences, Inc.
CTLA-4 VARIANT IMMUNOMODULATORY PROTEINS AND USES THEREOF

Abstract:

Provided herein are variant CTLA-4 polypeptides and immunomodulatory proteins and nucleic acids encoding such proteins. The immunomodulatory proteins provide therapeutic utility for a variety of disease applications, including for treatment of autoimmune or inflammatory conditions. Compositions and methods for making and using such proteins are provided.