Alpine Immune Sciences, Inc.
PD-1 VARIANT IMMUNOMODULATORY PROTEINS AND USES THEREOF

Abstract:

Provided herein are immunomodulatory proteins comprising variant PD-1 polypeptides, nucleic acids encoding such proteins and engineered cells expressing such proteins. The immunomodulatory proteins provide therapeutic utility for a variety of immunological and oncological conditions. Compositions and methods for making and using such proteins are provided.