Applied Materials, Inc.
PROBES AND ASSAYS FOR FLUORESCENT IN-SITU HYBRIDIZATION IMAGING USING MULTIPLEXED FLUORESCENT SWITCHING

Abstract:

A readout probe for use in fluorescent in-situ hybridization imaging has a targeting portion to bind to a first hybridization sequence in an encoding probe that targets an analyte in a sample, a first fluorophore to emit light at a wavelength range, and a first cleaving region between the first fluorophore and the targeting portion.