Amgen Inc.
COMBINATION THERAPY OF CARDIAC MYOSIN ACTIVATOR AND SINUS NODE IF CURRENT INHIBITOR

Abstract:

Disclosed herein are combination therapies for the treatment of heart failure using a cardiac myosin activator, such as omecamtiv mecarbil, and a sinus node If current inhibitor, such as ivabradine. Also disclosed herein are compositions comprising a cardiac myosin activator and a sinus node If current inhibitor.