Amgen Inc.
SUBSTITUTED PYRIMIDINONES AS AGONISTS OF THE APJ RECEPTOR

Abstract:

Compounds of Formula I and Formula II, pharmaceutically acceptable salts thereof, stereoisomers of any of the foregoing, or mixtures thereof are agonists of the APJ Receptor and may have use in treating cardiovascular and other conditions. Compounds of Formula I and Formula II have the following structures: Figure I and Figure II where the definitions of the variables are provided herein. ##STR00001##