Amgen Inc.
Methods for treating a headache condition using anti-human PAC1 antibodies or antigen-binding fragments thereof

Abstract:

The present invention relates to neutralizing antibodies of the human pituitary adenylate cyclase activating polypeptide type I receptor (PAC1) and pharmaceutical compositions comprising such antibodies. Methods of treating or preventing headache conditions, such as migraine and cluster headache, using the neutralizing antibodies are also described.