Amyris, Inc.
Biosynthesis of compounds in yeast
Last updated:
Abstract:
Provided herein are genetically modified yeast cells capable of producing one or more human milk oligosaccharides. The yeast cells include one or more heterologous nucleic acids that encode enzymes of a human milk oligosaccharide biosynthetic pathway. The yeast cells do not include a heterologous nucleic acid encoding a fucokinase. Also provided are fermentation compositions including the disclosed genetically modified yeast cells, and related methods of producing and recovering human milk oligosaccharides generated by the yeast cells.
Status:
Grant
Type:
Utility
Filling date:
21 Nov 2018
Issue date:
31 Dec 2019