AnaptysBio, Inc.
Method of treating pustular psoriasis with antibodies directed against interleukin 36 receptor (IL-36R)
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Abstract:
The invention relates to an isolated immunoglobulin heavy chain polypeptide and an isolated immunoglobulin light chain polypeptide that bind to a protein encoded by the interleukin 36 receptor (IL-36R). The invention provides an IL-36R-binding agent that comprises the aforementioned immunoglobulin heavy chain polypeptide and immunoglobulin light chain polypeptide. The invention also provides related vectors, compositions, and methods of using the IL-36R-binding agent to treat a disorder or disease that is responsive to IL-36R inhibition, such as cancer, an infectious disease, or an autoimmune disease.
Status:
Grant
Type:
Utility
Filling date:
18 Nov 2019
Issue date:
28 Sep 2021