Aerpio Pharmaceuticals, Inc.
METHODS OF TREATING HYPERTENSION WITH ACTIVATORS OF TIE-2

Abstract:

Disclosed herein are methods for treating hypertension, pulmonary hypertension, and associated conditions using activators of Tie-2 and inhibitors of HPTP.beta.. The methods include decreasing systolic blood pressure, decreasing diastolic blood pressure, decreasing mean arterial pressure, and modulating vascularization in the lungs.