Atossa Therapeutics, Inc.
INTRADUCTAL METHODS OF TREATMENT OF BREAST DISORDERS

Abstract:

The present invention relates to intraductal methods and compositions for treating subjects having breast disorders. Compositions comprise repolarizing agents and polarization blockading agents capable of repolarizing M2-macrophages to M1-macrophages in the tumor microenvironment, decreasing M2-macrophages, increasing M1-macrophages and/or increasing sensitivity to chemotherapy in the subject.