Baxter International Inc.
SPRAY-DRIED THROMBIN AND METHODS OF USING AND MAKING SPRAY-DRIED THROMBIN

Abstract:

Spray-dried thrombin materials obtained from feedstock solutions comprising less than 5% by weight albumin and excluding trehalose or other excipients as well as methods of manufacturing the thrombin materials and methods of treating bleeding wounds are disclosed. The methods of use include applying reconstituted spray-dried thrombin topically to a bleeding site, optionally in conjunction with gelatin.