Becton, Dickinson and Company
SYSTEM AND METHOD FOR DIAGNOSING SENSOR PERFORMANCE USING ANALYTE-INDEPENDENT RATIOMETRIC SIGNALS

Abstract:

A system and method are provided for utilizing radiometric fluorescence detection to determine a glucose independent concentration value when measuring frequency bands that do not contain the system isosbestic point. Preferably two bands are chosen such that a first band is below the system isosbestic point, and a second band is above the system isosbestic point, and both points are sufficiently far from the frequency endpoints to maximize the signal to noise ratio.