Becton, Dickinson and Company
Polyurethane Based Medical Articles

Abstract:

Medical articles formed from a polyurethane-based resin including an ionically-charged modifier provide enhanced properties. The polyurethane-based resin is a reaction product of ingredients comprising: a diisocyanate; a diol chain extender; a polyglycol; and a cationic modifier incorporated into a backbone, as a side chain, or both of the polyurethane-based resin. Exemplary cationic modifier includes bis(2-hydroxyethyl)dimethylammonium chloride (BHDAC). Medical articles herein either have inherent antimicrobial and/or anti-fouling characteristics or can easily bond anionic active agents to provide desirable material properties, including antimicrobial and anti-fouling.