Bristol-Myers Squibb Company
Quinazolines as potassium ion channel inhibitors

Abstract:

A compound of formula I ##STR00001## wherein A, X, Y, Z, R.sub.1 and R.sub.24 are described herein. The compounds are useful as inhibitors of potassium channel function and in the treatment and prevention of arrhythmia, I.sub.Kur-associated disorders, and other disorders mediated by ion channel function.