Bristol-Myers Squibb Company
Tricyclic sulfone compound as a ROR gamma modulator

Abstract:

There is described a ROR.gamma. modulator of the formula (I), ##STR00001## or stereoisomers, pharmaceutically acceptable salts, solvates, or prodrugs thereof. Also provided are pharmaceutical compositions comprising the same. The compound of the invention may be useful in methods for modulating ROR.gamma. activity in a cell and methods for treating a subject suffering from a disease or disorder in which the subject would therapeutically benefit from modulation of ROR.gamma. activity, for example, autoimmune and/or inflammatory disorders.