Bristol-Myers Squibb Company
NOVEL SYNTHETIC OPTIONS TOWARDS THE MANUFACTURE OF (6R,10S)-10-{4-[5-CHLORO-2-(4-CHLORO-1H-1,2,3-TRIAZOL-1-YL)PHENYL]-6-OXO-- 1(6H)-PYRIMIDINYL}- 1-(DIFLUOROMETHYL)-6-METHYL-1,4,7,8,9,10-HEXAHYDRO-11,15-(METHENO)PYRAZOL- O[4,3-B][1,7]DIAZACYCLOTETRADECIN-5(6H)-ONE

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Abstract:

Highly efficient methods are provided for preparing key intermediates in the synthesis of Compound (I), which are broadly applicable and can provide selected components having a variety of substituents groups. ##STR00001##

Status:
Application
Type:

Utility

Filling date:

10 Apr 2020

Issue date:

12 May 2022