Bristol-Myers Squibb Company
USE OF ANTI-CTLA-4 ANTIBODIES WITH ENHANCED ADCC TO ENHANCE IMMUNE RESPONSE TO A VACCINE

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Abstract:

The present invention provides methods of enhancing immune response to a vaccine using variant forms of anti-CTLA-4 antibodies having enhanced ADCC activity. Variant anti-CTLA-4 antibodies for use in the present invention include nonfucosylated ipilimumab.

Status:
Application
Type:

Utility

Filling date:

13 Jan 2022

Issue date:

28 Apr 2022