Bristol-Myers Squibb Company
2H-pyrazolo[4,3-d]pyrimidine compounds as toll-like receptor 7 (TLR7) agonists and methods and uses therefor

Abstract:

Compounds according to formula II are useful as agonists of Toll-like receptor 7 (TLR7). ##STR00001## Such compounds can be used in cancer treatment, especially in combination with an anti-cancer immunotherapy agent, or as a vaccine adjuvant.