Bionano Genomics, Inc.
METHOD FOR DETECTING TARGET RNA BY UTILIZING NICKING/EXTENSION CHAIN REACTION SYSTEM- BASED ISOTHERMAL NUCLEIC ACID AMPLIFICATION
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Abstract:
The present invention relates to a detection method for detecting a target RNA contained in a sample with high sensitivity by using nicking/extension chain reaction system-based isothermal nucleic acid amplification (NESBA) that uses activity of a cleavage enzyme and a DNA polymerase. The NESBA of the present invention is a new concept isothermal target RNA detection method that realizes higher amplification efficiency than the existing NASBA technology and is deemed to be utilizable as a new concept diagnosis technology that can replace conventional target RNA detection technologies.
Status:
Application
Type:
Utility
Filling date:
31 Dec 2018
Issue date:
25 Nov 2021