Calithera Biosciences, Inc.
COMBINATION THERAPY WITH GLUTAMINASE INHIBITORS

Abstract:

The invention relates to methods of treating cancer or myeloproliferative diseaseswith a combination of a glutaminase inhibitor and an anticancer agent selected from cabozantinib, crizotinib, and axitinib. The invention further relates to methods of treating cancer or myeloproliferative diseases that are resistant to one or more anticancer agents.