ChemoCentryx, Inc.
METHODS OF TREATING RESPIRATORY DISEASES USING C5a INHIBITORS

Abstract:

Provided herein are methods of treating a respiratory disease in a subject in need thereof by administering an effective amount of a small molecule C5a inhibitor. Also provided herein are methods of treating coronavirus disease 2019 (COVID-19) in a subject in need thereof by administering an effective amount of a small molecule C5a inhibitor. In some embodiments, the small molecule C5a inhibitor is a compound of Formula (I), Formula (II), Formula (III), Formula (IV) or an embodiment described herein.