ChemoCentryx, Inc.
Heteroaryl sulfonamides and CCR2/CCR9
Last updated:
Abstract:
Compounds are provided that act as potent antagonists of the CCR2 receptor. Animal testing demonstrates that these compounds are useful for treating inflammation, a hallmark disease for CCR2. The compounds are generally aryl sulfonamide derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR2-mediated diseases, and as controls in assays for the identification of CCR2 antagonists.
Status:
Grant
Type:
Utility
Filling date:
10 Jan 2020
Issue date:
6 Sep 2022